Review



mx 1 cells  (CLS Cell Lines Service GmbH)


Bioz Verified Symbol CLS Cell Lines Service GmbH is a verified supplier
Bioz Manufacturer Symbol CLS Cell Lines Service GmbH manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    CLS Cell Lines Service GmbH mx 1 cells
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mx 1 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mx 1 cells/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    mx 1 cells - by Bioz Stars, 2025-04
    90/100 stars

    Images

    1) Product Images from "Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition"

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    Journal: Oncotarget

    doi: 10.18632/oncotarget.25184

    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Figure Legend Snippet: The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Techniques Used:

    The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.
    Figure Legend Snippet: The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Techniques Used: Expressing, Western Blot



    Similar Products

    mx 1 cells  (CLS Cell Lines Service GmbH)
    90
    CLS Cell Lines Service GmbH mx 1 cells
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mx 1 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mx 1 cells/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    mx 1 cells - by Bioz Stars, 2025-04
    90/100 stars
    		  Buy from Supplier
    mammary carcinoma xenografts  (CLS Cell Lines Service GmbH)
    90
    CLS Cell Lines Service GmbH mammary carcinoma xenografts
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Mammary Carcinoma Xenografts, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mammary carcinoma xenografts/product/CLS Cell Lines Service GmbH
    Average 90 stars, based on 1 article reviews
    mammary carcinoma xenografts - by Bioz Stars, 2025-04
    90/100 stars
    		  Buy from Supplier
    300296 syringe bd luer lok  (Becton Dickinson)
    86
    Becton Dickinson 300296 syringe bd luer lok
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    300296 Syringe Bd Luer Lok, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/300296 syringe bd luer lok/product/Becton Dickinson
    Average 86 stars, based on 1 article reviews
    300296 syringe bd luer lok - by Bioz Stars, 2025-04
    86/100 stars
    		  Buy from Supplier
    300296 syringe bd luer lok  (Merck KGaA)
    86
    Merck KGaA 300296 syringe bd luer lok
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    300296 Syringe Bd Luer Lok, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/300296 syringe bd luer lok/product/Merck KGaA
    Average 86 stars, based on 1 article reviews
    300296 syringe bd luer lok - by Bioz Stars, 2025-04
    86/100 stars
    		  Buy from Supplier
    syringes becton dickinson franklin lakes ny cat 300296  (Becton Dickinson)
    86
    Becton Dickinson syringes becton dickinson franklin lakes ny cat 300296
    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and <t>Mx-1</t> cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.
    Syringes Becton Dickinson Franklin Lakes Ny Cat 300296, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/syringes becton dickinson franklin lakes ny cat 300296/product/Becton Dickinson
    Average 86 stars, based on 1 article reviews
    syringes becton dickinson franklin lakes ny cat 300296 - by Bioz Stars, 2025-04
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Journal: Oncotarget

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    doi: 10.18632/oncotarget.25184

    Figure Lengend Snippet: The combinatory effect of eribulin (ERI) and paclitaxel (PTX) on MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells was tested using WST assays. ( A ) Sensitivity to PTX in the presence or absence of low doses of ERI (upper panels for each cell line) and sensitivity to ERI in the presence or absence of low doses of PTX (lower panels for each cell line). Closed circles (●) indicate control, closed triangles (▲) indicate 0.1 nM (MDA-MB-231 and Hs578T cells) or 0.05 nM (MDA-MB-157 and Mx-1 cells) of ERI, open circles (○) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of ERI, closed squares (■) indicate 0.1 nM (MDA-MB-157 and Mx-1 cells), 0.2 nM (MDA-MB-231 cells), or 0.5 nM (Hs578T cells) of PTX, and open squares (□) indicate 0.3 nM (MDA-MB-157 and Mx-1 cells), 0.5 nM (MDA-MB-231 cells), or 1.0 nM (Hs578T cells) of PTX. The error bars represent the standard deviations of the values obtained; experiments were performed in triplicate. ( B ) The experimental data were plotted on an isobologram. The dots located below, on, or above the diagonal line indicate synergistic, additive, and antagonistic effects, respectively.

    Article Snippet: Three TNBC cell lines (MDA-MB-231, Hs578T, and MDA-MB-157) were purchased from the American Type Cell Collection (Manassas, VA), and Mx-1 cells were purchased from CLS Cell Lines Service (Eppelheim, Germany) in 2016, and passaged in our laboratory for less than 6 months after receipt or resuscitation.

    Techniques:

    The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Journal: Oncotarget

    Article Title: Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition

    doi: 10.18632/oncotarget.25184

    Figure Lengend Snippet: The expression of epithelial and mesenchymal markers was studied by western blotting. Representative results of western blot analyses are shown. β-Actin was used as a loading control. The experiments were performed independently at least three times, and one representative blot is provided in the figures. ( A ) Expression of EMT markers in MDA-MB-231, Hs578T, MDA-MB-157, and Mx-1 cells treated with eribulin (ERI; 0.1 and 0.2 nM), paclitaxel (PTX; 0.5 and 1 nM), or both (ERI; 0.2 nM and PTX; 1 nM) for 96 h. ( B ) Expression of EMT markers in MDA-MB-231, Hs578T cells treated with ERI (0.2 nM) or PTX (1 nM) for 24 h and 48 h.

    Article Snippet: Three TNBC cell lines (MDA-MB-231, Hs578T, and MDA-MB-157) were purchased from the American Type Cell Collection (Manassas, VA), and Mx-1 cells were purchased from CLS Cell Lines Service (Eppelheim, Germany) in 2016, and passaged in our laboratory for less than 6 months after receipt or resuscitation.

    Techniques: Expressing, Western Blot