intellicage systems  (TSE systems)


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    TSE systems intellicage systems
    <t>IntelliCage</t> activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.
    Intellicage Systems, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    intellicage systems - by Bioz Stars, 2023-06
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    1) Product Images from "Nonmotor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease"

    Article Title: Nonmotor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease

    Journal: bioRxiv

    doi: 10.1101/2023.01.23.525182

    IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.
    Figure Legend Snippet: IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.

    Techniques Used: Activity Assay, Mutagenesis

    intellicage systems  (TSE systems)


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    TSE systems intellicage systems
    <t>IntelliCage</t> activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.
    Intellicage Systems, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage systems/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage systems - by Bioz Stars, 2023-06
    95/100 stars

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    1) Product Images from "Nonmotor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease"

    Article Title: Nonmotor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease

    Journal: bioRxiv

    doi: 10.1101/2023.01.23.525182

    IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.
    Figure Legend Snippet: IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.

    Techniques Used: Activity Assay, Mutagenesis

    intellicage  (TSE systems)


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    TSE systems intellicage
    <t>Intellicage</t> behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.
    Intellicage, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "Modulation of GABA B receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks"

    Article Title: Modulation of GABA B receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

    Journal: Frontiers in Behavioral Neuroscience

    doi: 10.3389/fnbeh.2022.1042227

    Intellicage behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.
    Figure Legend Snippet: Intellicage behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.

    Techniques Used:

    Intellicage behavioral testing: overall results (sum of all 8 days of testing). (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Number of correct visits in chamber position learning 1. (E) Number of correct visits in chamber position learning 2. (F) Percentage of correct visits in chamber position learning 1. (G) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. The asterisks indicate significance against the NaCl group in (A–E) or against chance level (25%) in (F,G) ** p = 0.01; *** p = 0.001; **** p = 0.0001.
    Figure Legend Snippet: Intellicage behavioral testing: overall results (sum of all 8 days of testing). (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Number of correct visits in chamber position learning 1. (E) Number of correct visits in chamber position learning 2. (F) Percentage of correct visits in chamber position learning 1. (G) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. The asterisks indicate significance against the NaCl group in (A–E) or against chance level (25%) in (F,G) ** p = 0.01; *** p = 0.001; **** p = 0.0001.

    Techniques Used:

    Intellicage behavioral testing: daily results. (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Percentage of correct visits in chamber position learning 1. (E) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. N = 10 rats/group.
    Figure Legend Snippet: Intellicage behavioral testing: daily results. (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Percentage of correct visits in chamber position learning 1. (E) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. N = 10 rats/group.

    Techniques Used:

    intellicage system  (TSE systems)


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    TSE systems intellicage system
    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    intellicage system  (TSE systems)


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    TSE systems intellicage system
    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage system/product/TSE systems
    Average 95 stars, based on 1 article reviews
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    intellicage system - by Bioz Stars, 2023-06
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    intellicage  (TSE systems)


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    TSE systems intellicage
    (A) Overview of <t>IntelliCage</t> apparatus. (B) Group composition of mice housed and tested in each IntelliCage apparatus. (C) Behavioral sequencing task. Mice were allowed to obtain water reward for 4 seconds when they visited an “active” rewarded corner (blue circle). The location of the active rewarded corner was alternately switched between the two diagonally positioned corners each time the mouse received a reward. Thus, the mice had to acquire the behavioral sequence of alternating between the two rewarded corners to continuously obtain rewards. A visit to the never-rewarded corners (gray circles with a diagonal line) was counted as a discrimination error. (D) Serial reversal task. For each mouse, the assigned spatial patterns of the rewarded corners (seq. 1 or seq. 2) were reversed 11 times every 7 or 4 sessions. (E) Time-line of the experiment for each day. (F, G) Learning performance on the behavioral flexibility test. For the purpose of readability, data from the TC-0.6 and TC-3.0 groups of mice were separately plotted in F and G, respectively, whereas the data from the Control group are shown in F and G. Discrimination error rates (the number of discrimination errors in the first 100 corner visits in the session) are indicated as the means ± S.E.M. (n = 8/group). For each session, the individual mouse's discrimination error rate was transformed into a z-score calculated among all the mice. The bars in the insets in F and G indicate the averaged z-scores for each group in the first sessions of all the Revs (early stage of reversal learning) and in the second to fourth sessions of all Revs (late stage of reversal learning). * indicates a significant difference from the Control group ( P <0.05, ANOVA followed by Tukey's post hoc test).
    Intellicage, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage/product/TSE systems
    Average 95 stars, based on 1 article reviews
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    intellicage - by Bioz Stars, 2023-06
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    1) Product Images from "Executive Function Deficits and Social-Behavioral Abnormality in Mice Exposed to a Low Dose of Dioxin In Utero and via Lactation"

    Article Title: Executive Function Deficits and Social-Behavioral Abnormality in Mice Exposed to a Low Dose of Dioxin In Utero and via Lactation

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0050741

    (A) Overview of IntelliCage apparatus. (B) Group composition of mice housed and tested in each IntelliCage apparatus. (C) Behavioral sequencing task. Mice were allowed to obtain water reward for 4 seconds when they visited an “active” rewarded corner (blue circle). The location of the active rewarded corner was alternately switched between the two diagonally positioned corners each time the mouse received a reward. Thus, the mice had to acquire the behavioral sequence of alternating between the two rewarded corners to continuously obtain rewards. A visit to the never-rewarded corners (gray circles with a diagonal line) was counted as a discrimination error. (D) Serial reversal task. For each mouse, the assigned spatial patterns of the rewarded corners (seq. 1 or seq. 2) were reversed 11 times every 7 or 4 sessions. (E) Time-line of the experiment for each day. (F, G) Learning performance on the behavioral flexibility test. For the purpose of readability, data from the TC-0.6 and TC-3.0 groups of mice were separately plotted in F and G, respectively, whereas the data from the Control group are shown in F and G. Discrimination error rates (the number of discrimination errors in the first 100 corner visits in the session) are indicated as the means ± S.E.M. (n = 8/group). For each session, the individual mouse's discrimination error rate was transformed into a z-score calculated among all the mice. The bars in the insets in F and G indicate the averaged z-scores for each group in the first sessions of all the Revs (early stage of reversal learning) and in the second to fourth sessions of all Revs (late stage of reversal learning). * indicates a significant difference from the Control group ( P <0.05, ANOVA followed by Tukey's post hoc test).
    Figure Legend Snippet: (A) Overview of IntelliCage apparatus. (B) Group composition of mice housed and tested in each IntelliCage apparatus. (C) Behavioral sequencing task. Mice were allowed to obtain water reward for 4 seconds when they visited an “active” rewarded corner (blue circle). The location of the active rewarded corner was alternately switched between the two diagonally positioned corners each time the mouse received a reward. Thus, the mice had to acquire the behavioral sequence of alternating between the two rewarded corners to continuously obtain rewards. A visit to the never-rewarded corners (gray circles with a diagonal line) was counted as a discrimination error. (D) Serial reversal task. For each mouse, the assigned spatial patterns of the rewarded corners (seq. 1 or seq. 2) were reversed 11 times every 7 or 4 sessions. (E) Time-line of the experiment for each day. (F, G) Learning performance on the behavioral flexibility test. For the purpose of readability, data from the TC-0.6 and TC-3.0 groups of mice were separately plotted in F and G, respectively, whereas the data from the Control group are shown in F and G. Discrimination error rates (the number of discrimination errors in the first 100 corner visits in the session) are indicated as the means ± S.E.M. (n = 8/group). For each session, the individual mouse's discrimination error rate was transformed into a z-score calculated among all the mice. The bars in the insets in F and G indicate the averaged z-scores for each group in the first sessions of all the Revs (early stage of reversal learning) and in the second to fourth sessions of all Revs (late stage of reversal learning). * indicates a significant difference from the Control group ( P <0.05, ANOVA followed by Tukey's post hoc test).

    Techniques Used: Sequencing, Transformation Assay

    (A, B, C) Time-course of visit frequency in the first session of the day (21:50–22:40). The gray-colored period indicates the first five minutes (22:00–22:05) of the task. Vertical dotted lines indicate a peak in the group-averaged number of visits. (A, B, C) Time-course of visit frequency at the beginning of the session (21:50–22:40). Colored lines indicate the averaged visit frequency across all the sessions of each mouse, and the black thick lines indicate the average of each group: (A) Control, (B) TC-0.6, and (C) TC-3.0. (D) Visit frequency in the first five minutes throughout the sessions for each group (mean ± S.E.M., n = 8/group). (E, F) Average number of visits and duration of licking per session are shown as indices of daily water consumption. Error bars indicate ± S.E.M., n = 8/group. (G) A diagram of the competition task, in which the Control and TC-0.6 groups of mice (littermates of the mice used in the behavioral flexibility task) were subjected to the same water deprivation schedule as in the behavioral flexibility task. From days 1 to 4, all of the mice (a total of 14 mice, comprised of the Control and TC-0.6 groups) were housed in the same IntelliCage apparatus (a highly competitive condition). From days 5 to 8, each group of mice was housed separately in two different IntelliCage apparatuses (a less competitive condition). From days 9 to 12, all the mice were again housed in the same IntelliCage apparatus (a highly competitive condition). (H) Visit frequency in the first five minutes in the competition task. * and † indicate a significant difference from the Control group in the identical time period and from the TC-0.6 group on days 5 to 8, respectively. Error bars indicate ± S.E.M., n = 7/group.
    Figure Legend Snippet: (A, B, C) Time-course of visit frequency in the first session of the day (21:50–22:40). The gray-colored period indicates the first five minutes (22:00–22:05) of the task. Vertical dotted lines indicate a peak in the group-averaged number of visits. (A, B, C) Time-course of visit frequency at the beginning of the session (21:50–22:40). Colored lines indicate the averaged visit frequency across all the sessions of each mouse, and the black thick lines indicate the average of each group: (A) Control, (B) TC-0.6, and (C) TC-3.0. (D) Visit frequency in the first five minutes throughout the sessions for each group (mean ± S.E.M., n = 8/group). (E, F) Average number of visits and duration of licking per session are shown as indices of daily water consumption. Error bars indicate ± S.E.M., n = 8/group. (G) A diagram of the competition task, in which the Control and TC-0.6 groups of mice (littermates of the mice used in the behavioral flexibility task) were subjected to the same water deprivation schedule as in the behavioral flexibility task. From days 1 to 4, all of the mice (a total of 14 mice, comprised of the Control and TC-0.6 groups) were housed in the same IntelliCage apparatus (a highly competitive condition). From days 5 to 8, each group of mice was housed separately in two different IntelliCage apparatuses (a less competitive condition). From days 9 to 12, all the mice were again housed in the same IntelliCage apparatus (a highly competitive condition). (H) Visit frequency in the first five minutes in the competition task. * and † indicate a significant difference from the Control group in the identical time period and from the TC-0.6 group on days 5 to 8, respectively. Error bars indicate ± S.E.M., n = 7/group.

    Techniques Used:

    intellicage system  (TSE systems)


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    TSE systems intellicage system
    <t> IntelliCage </t> programs timeline overview.
    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage system/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage system - by Bioz Stars, 2023-06
    95/100 stars

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    1) Product Images from "Late-long-term potentiation magnitude, but not Aβ levels and amyloid pathology, is associated with behavioral performance in a rat knock-in model of Alzheimer disease"

    Article Title: Late-long-term potentiation magnitude, but not Aβ levels and amyloid pathology, is associated with behavioral performance in a rat knock-in model of Alzheimer disease

    Journal: Frontiers in Aging Neuroscience

    doi: 10.3389/fnagi.2022.1040576

    IntelliCage programs timeline overview.
    Figure Legend Snippet: IntelliCage programs timeline overview.

    Techniques Used: Sequencing

    intellicage system  (TSE systems)


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    TSE systems intellicage system

    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage system/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage system - by Bioz Stars, 2023-06
    95/100 stars

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    1) Product Images from "Development of an IntelliCage based Cognitive Bias Test for Mice"

    Article Title: Development of an IntelliCage based Cognitive Bias Test for Mice

    Journal: bioRxiv

    doi: 10.1101/2022.10.19.512853


    Figure Legend Snippet:

    Techniques Used:

    Home-cage based set-up based on the IntelliCage system. A: The set-up consisted of the IntelliCage used as the test-cage, which is connected through the AnimalGate to the home-cage. The IntelliCage was equipped with four conditioning corners and bedding. The home-cage was equipped with bedding, nesting, enrichment and food ad libitum (not shown here). The AnimalGate had three doors, one radio frequency identification (RFID) antenna. B: In addition, the AnimalGate had eight infrared barriers and one scale to measure the animal’s weight during each gate passage. C: Within the IntelliCage corners, water could be provided. In addition, each corner had one radio frequency identification antenna, one presence-sensor, one airpuff-valve, two water dispensers and two doors.
    Figure Legend Snippet: Home-cage based set-up based on the IntelliCage system. A: The set-up consisted of the IntelliCage used as the test-cage, which is connected through the AnimalGate to the home-cage. The IntelliCage was equipped with four conditioning corners and bedding. The home-cage was equipped with bedding, nesting, enrichment and food ad libitum (not shown here). The AnimalGate had three doors, one radio frequency identification (RFID) antenna. B: In addition, the AnimalGate had eight infrared barriers and one scale to measure the animal’s weight during each gate passage. C: Within the IntelliCage corners, water could be provided. In addition, each corner had one radio frequency identification antenna, one presence-sensor, one airpuff-valve, two water dispensers and two doors.

    Techniques Used:


    Figure Legend Snippet:

    Techniques Used:

    Corner conditioning group two. Number of nosepokes in percent made in response to two different tone-frequencies. The data for experimental day 23, 99, 104, 105 is missing due to technical problems with the IntelliCage system. No data from day 49 to 84 is available, because the mice were not in the home-cage based set-up as the set-up had to be maintained. From experimental day 85 the mice were kept in the set-up again. In order to habituate the mice to the set-up again, no sounds were played on days 85 to 98. On the y-axis, the number of nosepokes in percent is shown. The x-axis shows the experimental days. The dashed line marks the time point when the tone length was increased to one second. 0% = no negative tone, 5% = 5% negative tone probability, 10% = 10 percent negative tone probability, 16% = 16% negative tone probability, 20% = 20% negative tone probability, 33% = 33% negative tone probability, 50% = 50% negative tone probability
    Figure Legend Snippet: Corner conditioning group two. Number of nosepokes in percent made in response to two different tone-frequencies. The data for experimental day 23, 99, 104, 105 is missing due to technical problems with the IntelliCage system. No data from day 49 to 84 is available, because the mice were not in the home-cage based set-up as the set-up had to be maintained. From experimental day 85 the mice were kept in the set-up again. In order to habituate the mice to the set-up again, no sounds were played on days 85 to 98. On the y-axis, the number of nosepokes in percent is shown. The x-axis shows the experimental days. The dashed line marks the time point when the tone length was increased to one second. 0% = no negative tone, 5% = 5% negative tone probability, 10% = 10 percent negative tone probability, 16% = 16% negative tone probability, 20% = 20% negative tone probability, 33% = 33% negative tone probability, 50% = 50% negative tone probability

    Techniques Used:

    Individual learning success during conditioning when the negative tone-frequency was presented with a probability of 50%. The data of day 105 is missing due to technical problems with the IntelliCage system. Ro_ge_2 and ro_si_2 did not participate any longer in the experiment. Learning criterion 9 trials over 50% out of 12.
    Figure Legend Snippet: Individual learning success during conditioning when the negative tone-frequency was presented with a probability of 50%. The data of day 105 is missing due to technical problems with the IntelliCage system. Ro_ge_2 and ro_si_2 did not participate any longer in the experiment. Learning criterion 9 trials over 50% out of 12.

    Techniques Used:

    Measurement of body weight, IntelliCage corner visits and lick number over time. The x-axis shows the experimental days. On the y-axis first the body weight, second the lick number and third the visit number is shown. Different tones with different playback probabilities were presented throughout the experimental period (treatment). The data of experimental day −1, 23, 33, 98, 100, 104 and 105 are missing, due to technical issues. During experimental days 49 to 84 no tones were played.
    Figure Legend Snippet: Measurement of body weight, IntelliCage corner visits and lick number over time. The x-axis shows the experimental days. On the y-axis first the body weight, second the lick number and third the visit number is shown. Different tones with different playback probabilities were presented throughout the experimental period (treatment). The data of experimental day −1, 23, 33, 98, 100, 104 and 105 are missing, due to technical issues. During experimental days 49 to 84 no tones were played.

    Techniques Used:

    Corner conditioning group three. Number of nosepokes in percent made in response to two tone-frequencies. The data for experimental day 32 and 59 are missing due to technical problems with the IntelliCage system. There was an experimental break between day 47 and 56. After each treatment, no tones were presented. On the y-axis, the number of nosepokes in percent are shown. The x-axis shows the experimental days. During the experimental time period, the tones were presented with different probabilities. 0% = no negative tone, 20% = 20% negative tone probability, 50% = 50% negative tone probability, CBT b = cognitive bias measurement baseline, CBT n = cognitive bias measurement under negative conditions with less bedding and nesting, no enrichment and daily restraining
    Figure Legend Snippet: Corner conditioning group three. Number of nosepokes in percent made in response to two tone-frequencies. The data for experimental day 32 and 59 are missing due to technical problems with the IntelliCage system. There was an experimental break between day 47 and 56. After each treatment, no tones were presented. On the y-axis, the number of nosepokes in percent are shown. The x-axis shows the experimental days. During the experimental time period, the tones were presented with different probabilities. 0% = no negative tone, 20% = 20% negative tone probability, 50% = 50% negative tone probability, CBT b = cognitive bias measurement baseline, CBT n = cognitive bias measurement under negative conditions with less bedding and nesting, no enrichment and daily restraining

    Techniques Used:

    Measurement of body weight, IntelliCage corner visits and lick number over time. The x-axis shows the experimental days. On the y-axis, first the body weight, second the lick number and third the visit number is shown. Different tones with different playback probabilities were presented throughout the experimental period (treatment). The data of experimental day 32, 59 and 92 is missing, due to technical issues.
    Figure Legend Snippet: Measurement of body weight, IntelliCage corner visits and lick number over time. The x-axis shows the experimental days. On the y-axis, first the body weight, second the lick number and third the visit number is shown. Different tones with different playback probabilities were presented throughout the experimental period (treatment). The data of experimental day 32, 59 and 92 is missing, due to technical issues.

    Techniques Used:

    intellicage tse systems  (TSE systems)


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    TSE systems intellicage tse systems
    Intellicage Tse Systems, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    intellicage  (TSE systems)


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    TSE systems intellicage
    Intellicage, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage/product/TSE systems
    Average 95 stars, based on 1 article reviews
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    intellicage - by Bioz Stars, 2023-06
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    intellicage system  (TSE systems)


    Bioz Verified Symbol TSE systems is a verified supplier
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    TSE systems intellicage system
    All three variables associated with the positive valence domain. A Sucrose preference quantified in an <t>IntelliCage</t> task, measured as preference score from −1 (absolute avoidance) to 1 (exclusive preference). B The same preference score representing preference for the rewarded corner in a spatial positive reinforcement-learning paradigm in the IntelliCage (place learning). C Path choice quantified as rotation rate in the open field test was interpreted as nervous or hectic behavior. D Center time in the open field test and E baseline freezing behavior in the fear conditioning test were used as proxies of anxiety level. F Time immobile in the tail suspension test quantifying the absence of struggling behavior. Data are shown as box plots with whiskers extending to no more than 1.5-fold IQR; * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant; p -values are FDR-adjusted and refer to Wilk’s lambda testing two-way ANOVA; n = 19/19/30/30; Plc placebo, Sp spironolactone treatment, Apz aripiprazole treatment, S spironolactone term, A aripiprazole term, SxA interaction term, P-S spironolactone effect in placebo-treated mice, A-S spironolactone effect in aripiprazole-treated mice.
    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage system/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage system - by Bioz Stars, 2023-06
    95/100 stars

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    1) Product Images from "Spironolactone alleviates schizophrenia-related reversal learning in Tcf4 transgenic mice subjected to social defeat"

    Article Title: Spironolactone alleviates schizophrenia-related reversal learning in Tcf4 transgenic mice subjected to social defeat

    Journal: Schizophrenia

    doi: 10.1038/s41537-022-00290-4

    All three variables associated with the positive valence domain. A Sucrose preference quantified in an IntelliCage task, measured as preference score from −1 (absolute avoidance) to 1 (exclusive preference). B The same preference score representing preference for the rewarded corner in a spatial positive reinforcement-learning paradigm in the IntelliCage (place learning). C Path choice quantified as rotation rate in the open field test was interpreted as nervous or hectic behavior. D Center time in the open field test and E baseline freezing behavior in the fear conditioning test were used as proxies of anxiety level. F Time immobile in the tail suspension test quantifying the absence of struggling behavior. Data are shown as box plots with whiskers extending to no more than 1.5-fold IQR; * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant; p -values are FDR-adjusted and refer to Wilk’s lambda testing two-way ANOVA; n = 19/19/30/30; Plc placebo, Sp spironolactone treatment, Apz aripiprazole treatment, S spironolactone term, A aripiprazole term, SxA interaction term, P-S spironolactone effect in placebo-treated mice, A-S spironolactone effect in aripiprazole-treated mice.
    Figure Legend Snippet: All three variables associated with the positive valence domain. A Sucrose preference quantified in an IntelliCage task, measured as preference score from −1 (absolute avoidance) to 1 (exclusive preference). B The same preference score representing preference for the rewarded corner in a spatial positive reinforcement-learning paradigm in the IntelliCage (place learning). C Path choice quantified as rotation rate in the open field test was interpreted as nervous or hectic behavior. D Center time in the open field test and E baseline freezing behavior in the fear conditioning test were used as proxies of anxiety level. F Time immobile in the tail suspension test quantifying the absence of struggling behavior. Data are shown as box plots with whiskers extending to no more than 1.5-fold IQR; * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant; p -values are FDR-adjusted and refer to Wilk’s lambda testing two-way ANOVA; n = 19/19/30/30; Plc placebo, Sp spironolactone treatment, Apz aripiprazole treatment, S spironolactone term, A aripiprazole term, SxA interaction term, P-S spironolactone effect in placebo-treated mice, A-S spironolactone effect in aripiprazole-treated mice.

    Techniques Used:

    A General locomotor activity level in the IntelliCage (IC) was quantified as instantaneous visit frequency. B In addition, the nocturnality of activity in the IC was measured with a preference (nocturnality) score similar to sucrose preference, where −1 indicates exclusive daytime activity and +1 only nighttime activity. C , D Moreover, spontaneous, novelty-induced activity was assessed as (C) total number of choices in the Y-maze test (YM) and (D) mean speed in the open field test (OF). E , F Circadian activity distribution in 1-h bins, quantified as instantaneous frequency. The data is shown as group (line) and its standard error (ribbon). Data are shown as box plots with whiskers extending to no more than 1.5-fold IQR; * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant; p -values are FDR-adjusted and refer to Wilk’s lambda testing two-way ANOVA; n = 19/19/30/30; Plc placebo, Spl spironolactone treatment, Apz aripiprazole treatment, S spironolactone term, A aripiprazole term, SxA interaction term, P-S spironolactone effect in placebo-treated mice, A-S spironolactone effect in aripiprazole-treated mice.
    Figure Legend Snippet: A General locomotor activity level in the IntelliCage (IC) was quantified as instantaneous visit frequency. B In addition, the nocturnality of activity in the IC was measured with a preference (nocturnality) score similar to sucrose preference, where −1 indicates exclusive daytime activity and +1 only nighttime activity. C , D Moreover, spontaneous, novelty-induced activity was assessed as (C) total number of choices in the Y-maze test (YM) and (D) mean speed in the open field test (OF). E , F Circadian activity distribution in 1-h bins, quantified as instantaneous frequency. The data is shown as group (line) and its standard error (ribbon). Data are shown as box plots with whiskers extending to no more than 1.5-fold IQR; * p < 0.05, ** p < 0.01, *** p < 0.001, n.s. not significant; p -values are FDR-adjusted and refer to Wilk’s lambda testing two-way ANOVA; n = 19/19/30/30; Plc placebo, Spl spironolactone treatment, Apz aripiprazole treatment, S spironolactone term, A aripiprazole term, SxA interaction term, P-S spironolactone effect in placebo-treated mice, A-S spironolactone effect in aripiprazole-treated mice.

    Techniques Used: Activity Assay

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    TSE systems intellicage systems
    <t>IntelliCage</t> activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.
    Intellicage Systems, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage systems/product/TSE systems
    Average 95 stars, based on 1 article reviews
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    intellicage systems - by Bioz Stars, 2023-06
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    intellicage  (TSE systems)
    95
    TSE systems intellicage
    <t>Intellicage</t> behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.
    Intellicage, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage - by Bioz Stars, 2023-06
    95/100 stars
    		  Buy from Supplier
    intellicage system  (TSE systems)
    95
    TSE systems intellicage system
    <t>Intellicage</t> behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.
    Intellicage System, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage system/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage system - by Bioz Stars, 2023-06
    95/100 stars
    		  Buy from Supplier
    intellicage tse systems  (TSE systems)
    95
    TSE systems intellicage tse systems
    <t>Intellicage</t> behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.
    Intellicage Tse Systems, supplied by TSE systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intellicage tse systems/product/TSE systems
    Average 95 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    intellicage tse systems - by Bioz Stars, 2023-06
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.

    Journal: bioRxiv

    Article Title: Nonmotor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson’s disease

    doi: 10.1101/2023.01.23.525182

    Figure Lengend Snippet: IntelliCage activity in female TIF-IA DATCreERT2 and control mice. The graphs show (a, b) activity in the cage, (c) fraction of choices of the higher reward probability and (d) saccharin preference binned over 16-day periods roughly corresponding to the time points from gait testing. Points represent the group mean, and error bars are SEM. Stars indicate significant difference mutant vs. control, t -tests with Bonferroni correction for multiple tests, p <0.05.

    Article Snippet: Briefly, female TIF-IA DATCreERT2 mice were implanted subcutaneously with PICO UNO radio-frequency identification (RFID) transponders 4 weeks after mutation induction and placed in groups of 11 in two automated IntelliCage systems (TSE Systems, Germany).

    Techniques: Activity Assay, Mutagenesis

    Intellicage behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: Modulation of GABA B receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

    doi: 10.3389/fnbeh.2022.1042227

    Figure Lengend Snippet: Intellicage behavioral testing experimental design. (A) Free exploration. (B) Basic nosepoke learning. (C) Skilled nosepoke learning. (D) Chamber position learning 1. (E) Chamber position learning 2. (F) Door position learning 1. (G) Door position learning 2.

    Article Snippet: The Intellicage (TSE Systems GmbH, Germany) is a new automated group-testing system that allows standardized rodent behavioral phenotyping in a social context and without interaction with the experimenter during the test.

    Techniques:

    Intellicage behavioral testing: overall results (sum of all 8 days of testing). (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Number of correct visits in chamber position learning 1. (E) Number of correct visits in chamber position learning 2. (F) Percentage of correct visits in chamber position learning 1. (G) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. The asterisks indicate significance against the NaCl group in (A–E) or against chance level (25%) in (F,G) ** p = 0.01; *** p = 0.001; **** p = 0.0001.

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: Modulation of GABA B receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

    doi: 10.3389/fnbeh.2022.1042227

    Figure Lengend Snippet: Intellicage behavioral testing: overall results (sum of all 8 days of testing). (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Number of correct visits in chamber position learning 1. (E) Number of correct visits in chamber position learning 2. (F) Percentage of correct visits in chamber position learning 1. (G) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. The asterisks indicate significance against the NaCl group in (A–E) or against chance level (25%) in (F,G) ** p = 0.01; *** p = 0.001; **** p = 0.0001.

    Article Snippet: The Intellicage (TSE Systems GmbH, Germany) is a new automated group-testing system that allows standardized rodent behavioral phenotyping in a social context and without interaction with the experimenter during the test.

    Techniques:

    Intellicage behavioral testing: daily results. (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Percentage of correct visits in chamber position learning 1. (E) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. N = 10 rats/group.

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: Modulation of GABA B receptors in the insula bidirectionally affects associative memory of epilectic rats in both spatial and non-spatial operant tasks

    doi: 10.3389/fnbeh.2022.1042227

    Figure Lengend Snippet: Intellicage behavioral testing: daily results. (A) Number of visits in free exploration. (B) Number of nosepokes in basic nosepoke learning. (C) Number of nosepokes in skilled nosepoke learning. (D) Percentage of correct visits in chamber position learning 1. (E) Percentage of correct visits in chamber position learning 2. N = 10 rats/group. N = 10 rats/group.

    Article Snippet: The Intellicage (TSE Systems GmbH, Germany) is a new automated group-testing system that allows standardized rodent behavioral phenotyping in a social context and without interaction with the experimenter during the test.

    Techniques: