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Journal: eLife
Article Title: BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD
doi: 10.7554/eLife.106342
Figure Lengend Snippet: ( a ,b ) Comparison of blood urea nitrogen (BUN) levels of kidneys of the Bicc1:Pkd2 crosses at postnatal day P14 and P21. ( c, d ) Comparison of kidney weight/body weight ratios (KW/BW) levels of kidneys of Bicc1:Pkd1 crosses and their respective BUN levels at postnatal day P14. ( e ) Immunoprecipitation of PC2 from kidneys of Bicc1 +/+ and Bicc1 Bpk/Bpk mice at postnatal day P4. 200 µg total protein from each sample was used to immunoprecipitate PC2 with 5 µg Ycc2 antibody and agarose-bound protein A/G. PC2 was detected using another antibody against Pkd2 (Sc-28331). Figure 4—figure supplement 1—source data 1. Original western blots for , indicating the relevant bands. Figure 4—figure supplement 1—source data 2. Original western blots for , indicating the relevant bands.
Article Snippet: Antibody , Anti-Polycystin-2 (D-3, mouse monoclonal) ,
Techniques: Comparison, Immunoprecipitation, Western Blot