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LMS percentiles for serum <t>sRANKL</t> ( a , boys; b , <t>girls),</t> <t>OPG</t> ( c ), and the sRANKL/OPG ratio ( d , boys; e, girls) according to age. The 2.5 th , 10 th , 25 th , 50 th (bold line), 75 th , 90 th , and 97.5 th percentiles are given
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LMS percentiles for serum sRANKL ( a , boys; b , girls), OPG ( c ), and the sRANKL/OPG ratio ( d , boys; e, girls) according to age. The 2.5 th , 10 th , 25 th , 50 th (bold line), 75 th , 90 th , and 97.5 th percentiles are given

Journal: Osteoporosis International

Article Title: LMS-based continuous pediatric reference values for soluble receptor activator of nuclear factor kappa B ligand (sRANKL) and osteoprotegerin (OPG) in the HARP cohort

doi: 10.1007/s00198-023-06959-5

Figure Lengend Snippet: LMS percentiles for serum sRANKL ( a , boys; b , girls), OPG ( c ), and the sRANKL/OPG ratio ( d , boys; e, girls) according to age. The 2.5 th , 10 th , 25 th , 50 th (bold line), 75 th , 90 th , and 97.5 th percentiles are given

Article Snippet: Serum sRANKL (Human Free soluble RANKL, BI-20462, Biomedica Immunoassays) and plasma OPG (Human Osteoprotegerin ELISA, #RD194003200, BioVendor) levels were determined in duplicate by sandwich enzyme-linked immunosorbent assays (ELISA) according to the manufacturer ́s protocol using Tecan 96-well plate reader (Tecan infinite M200 PRO). sRANKL and OPG concentrations were quantified with Magellan software (Magellan 7.2 SP1). and the sRANKL/OPG ratio was calculated for every subject.

Techniques:

Associations between sRANKL and OPG with anthropometric and mineral metabolism parameters in the HARP cohort. a-d: associations between sRANKL and OPG and serum phosphate z-scores in boys ( a : r = -0.171, p = 0.0342; c : r = 0.222, p = 0.0093) and girls ( b : r = -0.365, p < 0.0001; d : r = 0.274, p = 0.0044), respectively. e – g : associations between OPG plasma concentrations and standardized weight ( e : r = -0.266, p < 0.0001), BMI ( f : r = -0.239; p < 0.0001) and urinary phosphate to creatinine ratio ( g : r = -0.172; p = 0.0165). Pi, phosphate; crea, creatinine

Journal: Osteoporosis International

Article Title: LMS-based continuous pediatric reference values for soluble receptor activator of nuclear factor kappa B ligand (sRANKL) and osteoprotegerin (OPG) in the HARP cohort

doi: 10.1007/s00198-023-06959-5

Figure Lengend Snippet: Associations between sRANKL and OPG with anthropometric and mineral metabolism parameters in the HARP cohort. a-d: associations between sRANKL and OPG and serum phosphate z-scores in boys ( a : r = -0.171, p = 0.0342; c : r = 0.222, p = 0.0093) and girls ( b : r = -0.365, p < 0.0001; d : r = 0.274, p = 0.0044), respectively. e – g : associations between OPG plasma concentrations and standardized weight ( e : r = -0.266, p < 0.0001), BMI ( f : r = -0.239; p < 0.0001) and urinary phosphate to creatinine ratio ( g : r = -0.172; p = 0.0165). Pi, phosphate; crea, creatinine

Article Snippet: Serum sRANKL (Human Free soluble RANKL, BI-20462, Biomedica Immunoassays) and plasma OPG (Human Osteoprotegerin ELISA, #RD194003200, BioVendor) levels were determined in duplicate by sandwich enzyme-linked immunosorbent assays (ELISA) according to the manufacturer ́s protocol using Tecan 96-well plate reader (Tecan infinite M200 PRO). sRANKL and OPG concentrations were quantified with Magellan software (Magellan 7.2 SP1). and the sRANKL/OPG ratio was calculated for every subject.

Techniques: Clinical Proteomics