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TCI Tokyo Chemical Industry moxifloxacin hcl
Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of <t>moxifloxacin</t> (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed
Moxifloxacin Hcl, supplied by TCI Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 88/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/moxifloxacin hcl/product/TCI Tokyo Chemical Industry
Average 88 stars, based on 3 article reviews
Price from $9.99 to $1999.99
moxifloxacin hcl - by Bioz Stars, 2020-11
88/100 stars

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1) Product Images from "In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management"

Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

Journal: Experimental eye research

doi: 10.1016/j.exer.2013.10.009

Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of moxifloxacin (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed
Figure Legend Snippet: Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of moxifloxacin (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed

Techniques Used: Concentration Assay

3.3 Bi-directional transport of moxifloxacin
Figure Legend Snippet: 3.3 Bi-directional transport of moxifloxacin

Techniques Used:

Dose dependent moxifloxacin (10µM - 1mM) mediated inhibition of [ 14 C]-Erythromycin (0.25 µCi/mL) efflux across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD (n=4).
Figure Legend Snippet: Dose dependent moxifloxacin (10µM - 1mM) mediated inhibition of [ 14 C]-Erythromycin (0.25 µCi/mL) efflux across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD (n=4).

Techniques Used: Inhibition

Modulation of anticancer agents mediated caspase-3 activity on Y-79 cells by moxifloxacin. Values are expressed as mean ± SD (n=3). Moxifloxacin (MFX); Etoposide (ETP); Topotecan (TP); Vinblastine (VB).
Figure Legend Snippet: Modulation of anticancer agents mediated caspase-3 activity on Y-79 cells by moxifloxacin. Values are expressed as mean ± SD (n=3). Moxifloxacin (MFX); Etoposide (ETP); Topotecan (TP); Vinblastine (VB).

Techniques Used: Activity Assay

Modulation of etoposide (1–40 µM), topotecan (1–40 µM), and vinblastine (1–40 nM) cytotoxicity on Y-79 cells by moxifloxacin (500 µM). Values are expressed as mean ± SD (n=6).
Figure Legend Snippet: Modulation of etoposide (1–40 µM), topotecan (1–40 µM), and vinblastine (1–40 nM) cytotoxicity on Y-79 cells by moxifloxacin (500 µM). Values are expressed as mean ± SD (n=6).

Techniques Used:

Flow cytometry analysis using Annexin V (AV) and propidium iodide (PI) staining illustrating modulation of etoposide (ETP), topotecan (TP), and vinblastine (VB) mediated Y-79 cell apoptosis by moxifloxacin (MFX). Q1= PI positive cells (AV − PI +
Figure Legend Snippet: Flow cytometry analysis using Annexin V (AV) and propidium iodide (PI) staining illustrating modulation of etoposide (ETP), topotecan (TP), and vinblastine (VB) mediated Y-79 cell apoptosis by moxifloxacin (MFX). Q1= PI positive cells (AV − PI +

Techniques Used: Flow Cytometry, Cytometry, Staining

Cellular accumulation of [ 14 C]-Erythromycin (0.25 µCi/mL) alone and in presence of moxifloxacin (500 µM), GF120198 (2 µM) and MK571 (50 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD
Figure Legend Snippet: Cellular accumulation of [ 14 C]-Erythromycin (0.25 µCi/mL) alone and in presence of moxifloxacin (500 µM), GF120198 (2 µM) and MK571 (50 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD

Techniques Used:

2) Product Images from "Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells"

Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

Journal: The Journal of pharmacy and pharmacology

doi: 10.1111/jphp.12139

Inhibition of moxifloxacin uptake by monocarboxylate transporter inhibitors. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05) different from the control group. One-way analysis of
Figure Legend Snippet: Inhibition of moxifloxacin uptake by monocarboxylate transporter inhibitors. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05) different from the control group. One-way analysis of

Techniques Used: Inhibition, Standard Deviation

Inhibition of moxifloxacin uptake by metabolic inhibitors (ouabain and sodium azide) across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically significant for P ≤ 0.05.
Figure Legend Snippet: Inhibition of moxifloxacin uptake by metabolic inhibitors (ouabain and sodium azide) across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically significant for P ≤ 0.05.

Techniques Used: Inhibition, Standard Deviation

Effect of pH on cellular accumulation of moxifloxacin across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4).
Figure Legend Snippet: Effect of pH on cellular accumulation of moxifloxacin across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4).

Techniques Used: Standard Deviation

Liquid chromatography–mass spectrometry mass spectrum of moxifloxacin (m/z 402.2→384.2) using levofloxacin (m/z 362.2→344.2) as an internal standard.
Figure Legend Snippet: Liquid chromatography–mass spectrometry mass spectrum of moxifloxacin (m/z 402.2→384.2) using levofloxacin (m/z 362.2→344.2) as an internal standard.

Techniques Used: Liquid Chromatography, Mass Spectrometry

Concentration dependent uptake of moxifloxacin (0.5–120 μM) on ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). Open squares represents total uptake at 37 °C and open triangle represents saturable
Figure Legend Snippet: Concentration dependent uptake of moxifloxacin (0.5–120 μM) on ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). Open squares represents total uptake at 37 °C and open triangle represents saturable

Techniques Used: Concentration Assay, Standard Deviation

Cellular accumulation of moxifloxacin alone and in presence of salisylic acid, ofloxacin and L-lactic acid across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05)
Figure Legend Snippet: Cellular accumulation of moxifloxacin alone and in presence of salisylic acid, ofloxacin and L-lactic acid across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05)

Techniques Used: Standard Deviation

Inhibition of moxifloxacin uptake by protonophore (2,4-dinitrophenol), organic anion transporter inhibitor (4,4′-diisothiocyano-2,2′-stilbenedisulfonic acid) and sulfhydryl-modifying agents (N-Ethylmaleimide (NEM) and Dithiothreitol (DTT)).
Figure Legend Snippet: Inhibition of moxifloxacin uptake by protonophore (2,4-dinitrophenol), organic anion transporter inhibitor (4,4′-diisothiocyano-2,2′-stilbenedisulfonic acid) and sulfhydryl-modifying agents (N-Ethylmaleimide (NEM) and Dithiothreitol (DTT)).

Techniques Used: Inhibition

Chemical structure of moxifloxacin.
Figure Legend Snippet: Chemical structure of moxifloxacin.

Techniques Used:

Related Articles

Diagnostic Assay:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: .. Oven-dry a 50 mL round bottom flask containing a stir bar Cool to room temperature under nitrogen Add 0.89 g (5.8 mmol) silver nitrite Add 30 mL ether Purge the suspension with nitrogen for 10 minutes (see air-sensitive technique ) Add 1.07 g of 9-bromononanoic acid, allyl ester (3.9 mmol) to the stirred solution Stopper the flask with a glass stopper Cover the flask with aluminum foil to protect from light Stir at room temperature for 7 days Check reaction progress by TLC Filter the suspension through a plug of silica and Celite Remove the solvents by rotary evaporation Purify the crude material via flash chromatography (50–60 mL silica gel, ethyl acetate/hexanes, 0–5%) to obtain 9-nitrononanoic acid, allyl ester as the second fraction Theoretical yield 0.94 g; typical yield 0.66 g TLC (ethyl acetate/hexanes, 1:3) Rf = 0.50 1 H NMR : The product has a diagnostic triplet signal centered at δ4.33 ppm corresponding to the nitroalkyl methylene protons. ..

Chromatography:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: .. Oven-dry a 50 mL round bottom flask containing a stir bar Cool to room temperature under nitrogen Add 0.89 g (5.8 mmol) silver nitrite Add 30 mL ether Purge the suspension with nitrogen for 10 minutes (see air-sensitive technique ) Add 1.07 g of 9-bromononanoic acid, allyl ester (3.9 mmol) to the stirred solution Stopper the flask with a glass stopper Cover the flask with aluminum foil to protect from light Stir at room temperature for 7 days Check reaction progress by TLC Filter the suspension through a plug of silica and Celite Remove the solvents by rotary evaporation Purify the crude material via flash chromatography (50–60 mL silica gel, ethyl acetate/hexanes, 0–5%) to obtain 9-nitrononanoic acid, allyl ester as the second fraction Theoretical yield 0.94 g; typical yield 0.66 g TLC (ethyl acetate/hexanes, 1:3) Rf = 0.50 1 H NMR : The product has a diagnostic triplet signal centered at δ4.33 ppm corresponding to the nitroalkyl methylene protons. ..

Evaporation:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: .. Oven-dry a 50 mL round bottom flask containing a stir bar Cool to room temperature under nitrogen Add 0.89 g (5.8 mmol) silver nitrite Add 30 mL ether Purge the suspension with nitrogen for 10 minutes (see air-sensitive technique ) Add 1.07 g of 9-bromononanoic acid, allyl ester (3.9 mmol) to the stirred solution Stopper the flask with a glass stopper Cover the flask with aluminum foil to protect from light Stir at room temperature for 7 days Check reaction progress by TLC Filter the suspension through a plug of silica and Celite Remove the solvents by rotary evaporation Purify the crude material via flash chromatography (50–60 mL silica gel, ethyl acetate/hexanes, 0–5%) to obtain 9-nitrononanoic acid, allyl ester as the second fraction Theoretical yield 0.94 g; typical yield 0.66 g TLC (ethyl acetate/hexanes, 1:3) Rf = 0.50 1 H NMR : The product has a diagnostic triplet signal centered at δ4.33 ppm corresponding to the nitroalkyl methylene protons. ..

Nuclear Magnetic Resonance:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: .. Oven-dry a 50 mL round bottom flask containing a stir bar Cool to room temperature under nitrogen Add 0.89 g (5.8 mmol) silver nitrite Add 30 mL ether Purge the suspension with nitrogen for 10 minutes (see air-sensitive technique ) Add 1.07 g of 9-bromononanoic acid, allyl ester (3.9 mmol) to the stirred solution Stopper the flask with a glass stopper Cover the flask with aluminum foil to protect from light Stir at room temperature for 7 days Check reaction progress by TLC Filter the suspension through a plug of silica and Celite Remove the solvents by rotary evaporation Purify the crude material via flash chromatography (50–60 mL silica gel, ethyl acetate/hexanes, 0–5%) to obtain 9-nitrononanoic acid, allyl ester as the second fraction Theoretical yield 0.94 g; typical yield 0.66 g TLC (ethyl acetate/hexanes, 1:3) Rf = 0.50 1 H NMR : The product has a diagnostic triplet signal centered at δ4.33 ppm corresponding to the nitroalkyl methylene protons. ..

Thin Layer Chromatography:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: .. Oven-dry a 50 mL round bottom flask containing a stir bar Cool to room temperature under nitrogen Add 0.89 g (5.8 mmol) silver nitrite Add 30 mL ether Purge the suspension with nitrogen for 10 minutes (see air-sensitive technique ) Add 1.07 g of 9-bromononanoic acid, allyl ester (3.9 mmol) to the stirred solution Stopper the flask with a glass stopper Cover the flask with aluminum foil to protect from light Stir at room temperature for 7 days Check reaction progress by TLC Filter the suspension through a plug of silica and Celite Remove the solvents by rotary evaporation Purify the crude material via flash chromatography (50–60 mL silica gel, ethyl acetate/hexanes, 0–5%) to obtain 9-nitrononanoic acid, allyl ester as the second fraction Theoretical yield 0.94 g; typical yield 0.66 g TLC (ethyl acetate/hexanes, 1:3) Rf = 0.50 1 H NMR : The product has a diagnostic triplet signal centered at δ4.33 ppm corresponding to the nitroalkyl methylene protons. ..

other:

Article Title: Nitrated fatty acids: Synthesis and measurement
Article Snippet: 9-Bromononanoic acid (TCI America, Cat. No. B2323) Allyl alcohol (Sigma-Aldrich, Cat. No. 240532) Silver nitrite (Sigma-Aldrich, Cat. No. 227188) p -toluenesulfonic acid (Sigma-Aldrich, Cat. No. 402885) DBU (1, 8-Diazabicyclo[5.4.0]undec-7-ene) (Sigma-Aldrich, Cat. No. 139009) Acetic anhydride (Sigma-Aldrich, Cat. No. 242845) DMAP (4-dimethylaminopyridine) (Sigma-Aldrich, Cat. No. 107700) Sodium carbonate (Sigma-Aldrich, Cat. No. 223484) Toluene (Fisher Cat. No. AC17716) Palladium tetrakis(triphenylphosphine) (Strem, Cat. No. 46-2150) Formic acid (95%) (Sigma-Aldrich, Cat. No. F0507)

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    TCI Tokyo Chemical Industry moxifloxacin hcl
    Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of <t>moxifloxacin</t> (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed
    Moxifloxacin Hcl, supplied by TCI Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 88/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/moxifloxacin hcl/product/TCI Tokyo Chemical Industry
    Average 88 stars, based on 2 article reviews
    Price from $9.99 to $1999.99
    moxifloxacin hcl - by Bioz Stars, 2020-11
    88/100 stars
      Buy from Supplier

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    Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of moxifloxacin (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Time and concentration dependent cellular accumulation of [ 3 H]-Etoposide, [ 3 H]-Topotecan and [ 3 H]-Vinblastine (each 0.25 µCi/mL) alone and in presence of moxifloxacin (100 and 500 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques: Concentration Assay

    3.3 Bi-directional transport of moxifloxacin

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: 3.3 Bi-directional transport of moxifloxacin

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques:

    Dose dependent moxifloxacin (10µM - 1mM) mediated inhibition of [ 14 C]-Erythromycin (0.25 µCi/mL) efflux across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD (n=4).

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Dose dependent moxifloxacin (10µM - 1mM) mediated inhibition of [ 14 C]-Erythromycin (0.25 µCi/mL) efflux across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD (n=4).

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques: Inhibition

    Modulation of anticancer agents mediated caspase-3 activity on Y-79 cells by moxifloxacin. Values are expressed as mean ± SD (n=3). Moxifloxacin (MFX); Etoposide (ETP); Topotecan (TP); Vinblastine (VB).

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Modulation of anticancer agents mediated caspase-3 activity on Y-79 cells by moxifloxacin. Values are expressed as mean ± SD (n=3). Moxifloxacin (MFX); Etoposide (ETP); Topotecan (TP); Vinblastine (VB).

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques: Activity Assay

    Modulation of etoposide (1–40 µM), topotecan (1–40 µM), and vinblastine (1–40 nM) cytotoxicity on Y-79 cells by moxifloxacin (500 µM). Values are expressed as mean ± SD (n=6).

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Modulation of etoposide (1–40 µM), topotecan (1–40 µM), and vinblastine (1–40 nM) cytotoxicity on Y-79 cells by moxifloxacin (500 µM). Values are expressed as mean ± SD (n=6).

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques:

    Flow cytometry analysis using Annexin V (AV) and propidium iodide (PI) staining illustrating modulation of etoposide (ETP), topotecan (TP), and vinblastine (VB) mediated Y-79 cell apoptosis by moxifloxacin (MFX). Q1= PI positive cells (AV − PI +

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Flow cytometry analysis using Annexin V (AV) and propidium iodide (PI) staining illustrating modulation of etoposide (ETP), topotecan (TP), and vinblastine (VB) mediated Y-79 cell apoptosis by moxifloxacin (MFX). Q1= PI positive cells (AV − PI +

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques: Flow Cytometry, Cytometry, Staining

    Cellular accumulation of [ 14 C]-Erythromycin (0.25 µCi/mL) alone and in presence of moxifloxacin (500 µM), GF120198 (2 µM) and MK571 (50 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD

    Journal: Experimental eye research

    Article Title: In vitro moxifloxacin drug interaction with chemotherapeutics: implications for retinoblastoma management

    doi: 10.1016/j.exer.2013.10.009

    Figure Lengend Snippet: Cellular accumulation of [ 14 C]-Erythromycin (0.25 µCi/mL) alone and in presence of moxifloxacin (500 µM), GF120198 (2 µM) and MK571 (50 µM) across MDCK-MDR1 and MDCK-MRP2 cells. Values are expressed as mean ± SD

    Article Snippet: Levofloxacin and Moxifloxacin HCl were acquired from TCI America (Sunnyvale, CA, USA) and China respectively.

    Techniques:

    Inhibition of moxifloxacin uptake by monocarboxylate transporter inhibitors. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05) different from the control group. One-way analysis of

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Inhibition of moxifloxacin uptake by monocarboxylate transporter inhibitors. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05) different from the control group. One-way analysis of

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Inhibition, Standard Deviation

    Inhibition of moxifloxacin uptake by metabolic inhibitors (ouabain and sodium azide) across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically significant for P ≤ 0.05.

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Inhibition of moxifloxacin uptake by metabolic inhibitors (ouabain and sodium azide) across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically significant for P ≤ 0.05.

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Inhibition, Standard Deviation

    Effect of pH on cellular accumulation of moxifloxacin across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4).

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Effect of pH on cellular accumulation of moxifloxacin across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4).

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Standard Deviation

    Liquid chromatography–mass spectrometry mass spectrum of moxifloxacin (m/z 402.2→384.2) using levofloxacin (m/z 362.2→344.2) as an internal standard.

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Liquid chromatography–mass spectrometry mass spectrum of moxifloxacin (m/z 402.2→384.2) using levofloxacin (m/z 362.2→344.2) as an internal standard.

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Liquid Chromatography, Mass Spectrometry

    Concentration dependent uptake of moxifloxacin (0.5–120 μM) on ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). Open squares represents total uptake at 37 °C and open triangle represents saturable

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Concentration dependent uptake of moxifloxacin (0.5–120 μM) on ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). Open squares represents total uptake at 37 °C and open triangle represents saturable

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Concentration Assay, Standard Deviation

    Cellular accumulation of moxifloxacin alone and in presence of salisylic acid, ofloxacin and L-lactic acid across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05)

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Cellular accumulation of moxifloxacin alone and in presence of salisylic acid, ofloxacin and L-lactic acid across ARPE-19 cells. Values are expressed as mean ± standard deviation ( n = 4). *Data were considered statistically ( P ≤ 0.05)

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Standard Deviation

    Inhibition of moxifloxacin uptake by protonophore (2,4-dinitrophenol), organic anion transporter inhibitor (4,4′-diisothiocyano-2,2′-stilbenedisulfonic acid) and sulfhydryl-modifying agents (N-Ethylmaleimide (NEM) and Dithiothreitol (DTT)).

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Inhibition of moxifloxacin uptake by protonophore (2,4-dinitrophenol), organic anion transporter inhibitor (4,4′-diisothiocyano-2,2′-stilbenedisulfonic acid) and sulfhydryl-modifying agents (N-Ethylmaleimide (NEM) and Dithiothreitol (DTT)).

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: Inhibition

    Chemical structure of moxifloxacin.

    Journal: The Journal of pharmacy and pharmacology

    Article Title: Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells

    doi: 10.1111/jphp.12139

    Figure Lengend Snippet: Chemical structure of moxifloxacin.

    Article Snippet: Levofloxacin and Moxifloxacin were acquired from TCI America (Sunnyvale, California, USA) and Hubei Phoebe West Company Technology Co., Ltd (Mainland, China), respectively.

    Techniques: