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single-cell transcription
Single Cell Transcription, supplied by TranScrip Partners, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/transcriptomic+profiling/transcriptome+profiling+of+single+cells+from+retinal+organoids/pm31291572-123-3-7
Average 90 stars, based on 1 article reviews
Single Cell Transcription, supplied by TranScrip Partners, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/transcriptomic+profiling/transcriptome+profiling+of+single+cells+from+retinal+organoids/pm31291572-123-3-7
Average 90 stars, based on 1 article reviews
single-cell transcription - by Bioz Stars,
2026-10
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Cell Culture:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Gene Expression:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Mouse Assay:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article In Vitro:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Cell Differentiation:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Flow Cytometry:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Adoptive Transfer Assay:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Isolation:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Ex Vivo:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article RNA Sequencing:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Real-time Polymerase Chain Reaction:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Selection:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article Control:Article Title: Dissecting endometriosis by single-cell transcriptomic and genomic analysis. Article Snippet: It is unfortunately commonplace for patients with endometriosis (ectopic growth of endometrium-like tissue, typically in the ovaries or abdominal cavity) to suffer for years with symptoms such as chronic pelvic pain and infertility before they get a diagnosis.. Therapeutic options are limited, and they generally aim to suppress lesion activity rather than eradicate the lesions altogether, which has implications for future fertility and symptom persistence or recurrence.. The scarcity of genome-wide molecular datasets means that endometriosis ranks as one of the most poorly characterized diseases molecularly, which has undoubtedly hindered the development of new ways to shorten the time to diagnosis and treat the disease more effectively. Article Title: Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma Article Snippet: Nevertheless, recent work of Sridhar et al. demonstrated similar cellular composition between retinal organoids and fetal retina at equivalent stages of development.42 STAR+METHODS Detailed methods are provided in the online version of this paper and include the following: d KEY RESOURCES TABLE d RESOURCE AVAILABILITY B Lead contact B Material availability B Data and code availability d EXPERIMENTAL MODEL AND SUBJECT DETAILS B Participant recruitment d METHOD DETAILS Cell Genomics 2, 100142, June 8, 2022 9 10 Article ll OPEN ACCESS B Fibroblast culture d GENERATION, SELECTION, AND IPSC MAINTENANCE d DIFFERENTIATION OF iPSCs INTO RETINAL ORGANO- IDS d QUANTIFICATION AND STATISTICAL ANALYSIS B Transcriptome profiling of single cells from retinal orga- noids and cell-based quality control d SNP GENOTYPE ANALYSIS AND IMPUTATION d DEMULTIPLEXING OF CELL POOLS INTO INDIVIDUAL DONORS d AGGREGATION, NORMALIZATION AND DIMENSION- ALITY REDUCTION OF SCRNA-SEQ DATASETS d IDENTIFICATION AND ANNOTATION OF CELL SUBPOP- ULATIONS d IDENTIFICATION OF DIFFERENTIATION LINEAGES VIA PSEUDOTIME ANALYSIS d IDENTIFICATION OF Article Title: Glymphatic system clearance and Alzheimer's disease risk: a CSF proteome-wide study. Article Snippet: Duan T, Chu J, Hu F. Identification of Peripheral Blood GZMK + CD8 + T Cells As Biomarkers of Alzheimer’s Disease Based on Article Title: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Article Snippet: Upregulated genes in cells cultured on liver scaffolds relative to pancreatic scaffolds were compared with the Article Title: A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients. Article Snippet: Lee D, Cheng A, Lawlor N, Bolisetty M, Ucar D. Detection of correlated hidden factors from single Article Title: Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Article Snippet: Resource Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Article Title: Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling. Article Snippet: Article |
