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spatial transcriptomics st sequencing  (Spatial Transcriptomics Inc)

 
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    Spatial Transcriptomics Inc spatial transcriptomics st sequencing
    Spatial Transcriptomics St Sequencing, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptomics+sequencing+st+seq/sequencing+spatial+transcriptomics/pm40621801-42-0-0
    Average 86 stars, based on 1 article reviews
    spatial transcriptomics st sequencing - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    Spatial Transcriptomics:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. Spatial transcriptomics sequencing and data analysis Human biopsy samples were used for RNA extraction on frozen embedded tissues stored at − 80 ◦ C to obtain RNA which has good integrity for future spatial transcription experiments. ..

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Article Title: Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
    Article Snippet: Address correspondence to Daqiang Sun, M.D., Department of Thoracic Surgery, Tianjin Chest Hospital, No. 261, Taierzhuang South Rd., Jinnan District, Tianjin, 300222, China.. E-mail: sdqmdsr@163.com.. Tumor spread through air spaces (STAS) is a pathologic feature of lung cancer with prognostic significance, and it is also a cutting-edge hotspot in the clinical field of lung cancer.

    Article Title: Single-cell multi-omics analysis revealed the expansion of age-associated B cells in the pancreas of type 1 autoimmune pancreatitis patients.
    Article Snippet: .. Spatial transcriptomics sequencing and data processing Formalin-fixed paraffin-embedded (FFPE) 5-μm pancreatic lesion tissue sections from a representative AIP patient were used. ..

    Sequencing:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. Spatial transcriptomics sequencing and data analysis Human biopsy samples were used for RNA extraction on frozen embedded tissues stored at − 80 ◦ C to obtain RNA which has good integrity for future spatial transcription experiments. ..

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases.
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Article Title: Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
    Article Snippet: Address correspondence to Daqiang Sun, M.D., Department of Thoracic Surgery, Tianjin Chest Hospital, No. 261, Taierzhuang South Rd., Jinnan District, Tianjin, 300222, China.. E-mail: sdqmdsr@163.com.. Tumor spread through air spaces (STAS) is a pathologic feature of lung cancer with prognostic significance, and it is also a cutting-edge hotspot in the clinical field of lung cancer.

    Article Title: Association of Single-Nucleotide Polymorphisms on FURIN and EPHA2 Genes with the Risk and Prognosis of Undifferentiated Nasopharyngeal Cancer.
    Article Snippet: .. This becomes even more insightful when we know that APP has significant effects on cancer cell proliferation, migration, and invasion, potentially contributing to tumor progression in cervical squamous cell carcinoma, as demonstrated recently using a novel biotechnology called Spatial Transcriptomics Sequencing [68]. ..

    Article Title: Single-cell multi-omics analysis revealed the expansion of age-associated B cells in the pancreas of type 1 autoimmune pancreatitis patients.
    Article Snippet: .. Spatial transcriptomics sequencing and data processing Formalin-fixed paraffin-embedded (FFPE) 5-μm pancreatic lesion tissue sections from a representative AIP patient were used. ..

    Article Title: Multimodal therapeutic strategies against gastric cancer: from conventional treatments to tumor microenvironment targeting
    Article Snippet: .. Spatial transcriptomics (ST) sequencing technology was designated Technology of the Year in 2020. ..

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    RNA Extraction:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. Spatial transcriptomics sequencing and data analysis Human biopsy samples were used for RNA extraction on frozen embedded tissues stored at − 80 ◦ C to obtain RNA which has good integrity for future spatial transcription experiments. ..

    Gene Expression:

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases.
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    In Situ:

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases.
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    Article Title: The molecular mechanisms and therapeutic implications of PANoptosis in ischemic diseases
    Article Snippet: .. Spatial transcriptomics sequencing technology allows for the precise analysis of the spatial distribution patterns of PANoptosis-related gene expression at the tissue level in situ, revealing the spatially specific modes of PANoptosis regulation exhibited by different cell types within the tissue microenvironment. ..

    Cell Culture:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Enzyme-linked Immunosorbent Assay:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Immunohistochemistry:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Quantitative RT-PCR:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Western Blot:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Transmission Assay:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Electron Microscopy:

    Article Title: Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.
    Article Snippet: .. STAR★METHODS Detailed methods are provided in the online version of this paper and include the following: • KEY RESOURCES TABLE • EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS ○ Sex as a biological variable ○ Human samples ○ Animal experiments ○ Cell culture and treatment ○ Establishment of endometrial organoids • METHOD DETAILS ○ Spatial transcriptomics sequencing and data analysis ○ Trajectory analysis ○ Enzyme-linked immunosorbent assay (ELISA) ○ Adhesion assays ○ Immunohistochemistry and qualification ○ qRT-PCR analysis ○ Western blot analysis ○ Transmission electron microscopy • QUANTIFICATION AND STATISTICAL ANALYSIS SUPPLEMENTAL INFORMATION Supplemental information can be found online at https://doi.org/10.1016/j. xcrm.2025.102464. ..

    Incubation:

    Article Title: Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
    Article Snippet: Address correspondence to Daqiang Sun, M.D., Department of Thoracic Surgery, Tianjin Chest Hospital, No. 261, Taierzhuang South Rd., Jinnan District, Tianjin, 300222, China.. E-mail: sdqmdsr@163.com.. Tumor spread through air spaces (STAS) is a pathologic feature of lung cancer with prognostic significance, and it is also a cutting-edge hotspot in the clinical field of lung cancer.

    Labeling:

    Article Title: Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
    Article Snippet: Address correspondence to Daqiang Sun, M.D., Department of Thoracic Surgery, Tianjin Chest Hospital, No. 261, Taierzhuang South Rd., Jinnan District, Tianjin, 300222, China.. E-mail: sdqmdsr@163.com.. Tumor spread through air spaces (STAS) is a pathologic feature of lung cancer with prognostic significance, and it is also a cutting-edge hotspot in the clinical field of lung cancer.

    Migration:

    Article Title: Association of Single-Nucleotide Polymorphisms on FURIN and EPHA2 Genes with the Risk and Prognosis of Undifferentiated Nasopharyngeal Cancer.
    Article Snippet: .. This becomes even more insightful when we know that APP has significant effects on cancer cell proliferation, migration, and invasion, potentially contributing to tumor progression in cervical squamous cell carcinoma, as demonstrated recently using a novel biotechnology called Spatial Transcriptomics Sequencing [68]. ..

    Formalin-fixed Paraffin-Embedded:

    Article Title: Single-cell multi-omics analysis revealed the expansion of age-associated B cells in the pancreas of type 1 autoimmune pancreatitis patients.
    Article Snippet: .. Spatial transcriptomics sequencing and data processing Formalin-fixed paraffin-embedded (FFPE) 5-μm pancreatic lesion tissue sections from a representative AIP patient were used. ..



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    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial <t>transcriptome</t> displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.
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    Image Search Results


    Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Transcription programs of ccRCC cells in response to cuproptosis. A UMAP showing the 10 subtypes of 26,981 Epithelial cells; B heatmap showing inferred CNV of scRNA-seq dataset; C dot plot of the relative cellular proportions of Epithelial subtypes in each group; D GSEA analysis revealed the activated CRGs enriched in Normal Epithelial cells; E violin plot showing the relative CRGs score in each cancer subtype; F survival plot of HILPDA + ccRCC1 signature high and low group in the KIRC samples; G violin plots of HILPDA expression levels and hypoxia scores in each cancer subtypes; H spatial transcriptome displayed the distribution of CRGs, HILPDA + ccRCC1 signatures, hypoxia scores and HILPDA expression; I the regulon specificity scores of TFs in HILPDA + ccRCC1 subtype. The top 5 TFs ordered by scores were listed; J violin plot showing the expression levels of the top 5 TFs in HILPDA + ccRCC1 subtype across stage I–IV.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Expressing

    Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Journal: Discover Oncology

    Article Title: Characterization of cuproptosis signature in clear cell renal cell carcinoma by single cell and spatial transcriptome analysis

    doi: 10.1007/s12672-024-01162-2

    Figure Lengend Snippet: Dissection of immunosuppressive cells of cuproptosis-related tumor microenvironment. A UMAP showing the 16 subtypes of 99,210 Immune cells; B violin plot of the relative expression levels of the canocial markers in each subtype; C heatmap showing the enrichment of immune checkpoint and suppressive genes; D spatial transcriptome displayed the distribution of Treg, CD8_Exhausted and TAM signature scores; E heatmap showing the four gene expression patterns deduced by TDEseq analysis; F violin plots showing the relative expression levels of CRG scores in the immunosuppressive cells across different stages; G Chord diagram showing the number of interactions among the four subtypes; H Bubble plot showing the ligand-receptor pairs in the main subtype; I Heatmap showing the relative expression levels of key genes of the four subtypes among the different stages. The paired ligand-receptor shown in H were connected by lines.

    Article Snippet: The spatial transcriptome sequencing (ST-seq) dataset was obtained from Mendeley Data platform ( https://data.mendeley.com/datasets/g67bkbnhhg/1 ) and input to python environment.

    Techniques: Dissection, Expressing, Gene Expression