spatial transcriptomic data (10X Genomics)
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Spatial Transcriptomic Data, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics"
Article Title: Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics
Journal: Frontiers in Neuroscience
doi: 10.3389/fnins.2022.1086168
Figure Legend Snippet: Global Moran’s index revealing three spatial autocorrelation patterns. Clustered, z > 1.65 and P < 0.1; random, –1.65 < z < 1.65 and P > 0.1; dispersed, z < –1.65 and P < 0.1. ST, spatial transcriptomic; CI, confidence interval.
Techniques Used:
Figure Legend Snippet: Differentially expressed genes (DEGs) in the different brain regions. (A) Brain region. ROI indicates sensorimotor cortex. (B) Yellow area indicates sensorimotor cortex in HE images. (C) Arpp19 of ST map. (D) Hotspot of Arpp19 . (E) DEGs in the sensorimotor cortex. Ratio = The number of H-H spots in sensorimotor cortex/The total number of spots in the section. (F) Septicity of DEGs in the sensorimotor cortex. Ratio = The number of H-H spots in each region/The total number of H-H spots. (G) Marker genes of each brain region. ST, spatial transcriptomic.
Techniques Used: Marker
Figure Legend Snippet: Downregulated DEGs revealed by saSpatial. (A) Bubble plots of top20 DEGs. P -values are indicated by circle size; scale adjacent to the plot. The rate difference are indicated by color. NC, normal control. P, penumbra. Typical DEGs of (B) ischemic core and (C) penumbra. N = 3. ST, spatial transcriptomic; CI, confidence interval.
Techniques Used: Control
Figure Legend Snippet: Differentially expressed genes (DEGs) in the cortex layers. (A) Top 3 DEGs in the layers. (B) Typical DEGs. ST, spatial transcriptomic.
Techniques Used:
Figure Legend Snippet: Heterogenicity of DEGs within the ischemic cortex. (A) Six layers of cortex in the ischemic cortex. (B) Typical DEGs. (C) ST map and Hotspot of typical DEGs. ST, spatial transcriptomic.
Techniques Used:
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