spatial transcriptomic data (10X Genomics)
86
Structured Review
10X Genomics
spatial transcriptomic data
Spatial Transcriptomic Data, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/data+spatial+transcriptomic/pmc09745188-114-0-11
Average 86 stars, based on 1 article reviews
Spatial Transcriptomic Data, supplied by 10X Genomics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/spatial+transcriptomic+data+analysis/data+spatial+transcriptomic/pmc09745188-114-0-11
Average 86 stars, based on 1 article reviews
spatial transcriptomic data - by Bioz Stars,
2026-10
86/100 stars
Images
1) Product Images from "Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics"
Article Title: Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics
Journal: Frontiers in Neuroscience
doi: 10.3389/fnins.2022.1086168
Figure Legend Snippet: Global Moran’s index revealing three spatial autocorrelation patterns. Clustered, z > 1.65 and P < 0.1; random, –1.65 < z < 1.65 and P > 0.1; dispersed, z < –1.65 and P < 0.1. ST, spatial transcriptomic; CI, confidence interval.
Techniques Used:
Figure Legend Snippet: Differentially expressed genes (DEGs) in the different brain regions. (A) Brain region. ROI indicates sensorimotor cortex. (B) Yellow area indicates sensorimotor cortex in HE images. (C) Arpp19 of ST map. (D) Hotspot of Arpp19 . (E) DEGs in the sensorimotor cortex. Ratio = The number of H-H spots in sensorimotor cortex/The total number of spots in the section. (F) Septicity of DEGs in the sensorimotor cortex. Ratio = The number of H-H spots in each region/The total number of H-H spots. (G) Marker genes of each brain region. ST, spatial transcriptomic.
Techniques Used: Marker
Figure Legend Snippet: Downregulated DEGs revealed by saSpatial. (A) Bubble plots of top20 DEGs. P -values are indicated by circle size; scale adjacent to the plot. The rate difference are indicated by color. NC, normal control. P, penumbra. Typical DEGs of (B) ischemic core and (C) penumbra. N = 3. ST, spatial transcriptomic; CI, confidence interval.
Techniques Used: Control
Figure Legend Snippet: Differentially expressed genes (DEGs) in the cortex layers. (A) Top 3 DEGs in the layers. (B) Typical DEGs. ST, spatial transcriptomic.
Techniques Used:
Figure Legend Snippet: Heterogenicity of DEGs within the ischemic cortex. (A) Six layers of cortex in the ischemic cortex. (B) Typical DEGs. (C) ST map and Hotspot of typical DEGs. ST, spatial transcriptomic.
Techniques Used:
Related Articles
Spatial Transcriptomics:Article Title: Single-cell multiomics gene regulatory landscape reveals impaired spermatogonial stem cells and macrophage-driven inflammaging during testicular aging. Article Snippet: 29 Testicular aging is a key driver of declining male reproductive health, but a comprehensive 30 understanding of its underlying epigenetic drivers is lacking.. To address this, we construct a 31 multiomics aging atlas by integrating single-cell RNA sequencing, single-cell assay for 32 transposase-accessible chromatin sequencing (scATAC-seq), and spatial transcriptomics of 33 young and aged mouse testes.. Our analysis reveals that altered chromatin accessibility 34 accompanies transcriptional dysregulation and identifies spermatogonial stem cells (SSCs) as 35 the most epigenetically vulnerable population. Sequencing:Article Title: Single-cell multiomics gene regulatory landscape reveals impaired spermatogonial stem cells and macrophage-driven inflammaging during testicular aging. Article Snippet: 29 Testicular aging is a key driver of declining male reproductive health, but a comprehensive 30 understanding of its underlying epigenetic drivers is lacking.. To address this, we construct a 31 multiomics aging atlas by integrating single-cell RNA sequencing, single-cell assay for 32 transposase-accessible chromatin sequencing (scATAC-seq), and spatial transcriptomics of 33 young and aged mouse testes.. Our analysis reveals that altered chromatin accessibility 34 accompanies transcriptional dysregulation and identifies spermatogonial stem cells (SSCs) as 35 the most epigenetically vulnerable population. Article Title: Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment. Article Snippet: .. To minimize batch effects caused by differences in sequencing platforms and methodologies, all single-cell and Gene Expression:Article Title: Single-cell multiomics gene regulatory landscape reveals impaired spermatogonial stem cells and macrophage-driven inflammaging during testicular aging. Article Snippet: 29 Testicular aging is a key driver of declining male reproductive health, but a comprehensive 30 understanding of its underlying epigenetic drivers is lacking.. To address this, we construct a 31 multiomics aging atlas by integrating single-cell RNA sequencing, single-cell assay for 32 transposase-accessible chromatin sequencing (scATAC-seq), and spatial transcriptomics of 33 young and aged mouse testes.. Our analysis reveals that altered chromatin accessibility 34 accompanies transcriptional dysregulation and identifies spermatogonial stem cells (SSCs) as 35 the most epigenetically vulnerable population. Single Cell:Article Title: Spatial single-cell landscape of tumor-associated macrophages and their crosstalk with the tumor microenvironment. Article Snippet: .. To minimize batch effects caused by differences in sequencing platforms and methodologies, all single-cell and Article Title: The Role of Tumor Necrosis Factor Signaling in Atherosclerosis and Stroke Article Snippet: .. To characterise TNF signaling within atherosclerotic plaques, we analysed two publicly available datasets: (i) an integrated single-cell RNA-sequencing (scRNA-seq) atlas of 259,116 cells from human carotid, coronary, and femoral plaques (73 donors), and (ii) Xenium (10x Genomics) In Situ:Article Title: SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children. Article Snippet: .. Spatial transcriptomic profiling with Article Title: An antioxidant therapy elicits distinct transcriptome responses in 22q11-deleted upper layer cortical projection neurons. Article Snippet: .. To assess L 2/3 PN transcriptional responses that underlie NAC’s therapeutic effects in vivo, we first established that spatial Article Title: Won't you be my neighbor? Control of the immune response by stromal and immune cell microenvironments within the lymph node. Article Snippet: Efficacious immune responses require the coordinated encounter of rare antigen-specific adaptive lymphocytes with their cognate innate antigen-presenting cells (APCs) in space and time.. This spatiotemporal problem of immunity is solved by secondary lymphoid organs, such as lymph nodes (LNs), which coordinate adaptive immune responses by recruiting APCs and lymphocytes into close juxtaposition with tissue antigens drained from the periphery.. A central tenet to the overall function of the LN is the spatial organization of leukocytes into discrete microenvironments orchestrated by the mesenchymal and endothelial cells, collectively termed LN stromal cells (LNSCs). Formalin-fixed Paraffin-Embedded:Article Title: SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children. Article Snippet: .. Spatial transcriptomic profiling with In Vivo:Article Title: An antioxidant therapy elicits distinct transcriptome responses in 22q11-deleted upper layer cortical projection neurons. Article Snippet: .. To assess L 2/3 PN transcriptional responses that underlie NAC’s therapeutic effects in vivo, we first established that spatial RNA sequencing:Article Title: The Role of Tumor Necrosis Factor Signaling in Atherosclerosis and Stroke Article Snippet: .. To characterise TNF signaling within atherosclerotic plaques, we analysed two publicly available datasets: (i) an integrated single-cell RNA-sequencing (scRNA-seq) atlas of 259,116 cells from human carotid, coronary, and femoral plaques (73 donors), and (ii) Xenium (10x Genomics) |