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spatial transcriptome sequencing data analysis  (LC Bio Co Ltd)

 
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    Structured Review

    LC Bio Co Ltd spatial transcriptome sequencing data analysis
    Spatial Transcriptome Sequencing Data Analysis, supplied by LC Bio Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spatial+transcriptome+sequencing+data/rna+seq/pmc12211156-44-2-15
    Average 90 stars, based on 1 article reviews
    spatial transcriptome sequencing data analysis - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    other:

    Article Title: m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy
    Article Snippet: Subsequently, LC-bio Co., Ltd. (Hangzhou, China) was commissioned to perform high-throughput sequencing of BEAS-2B-As model cells and normal BEAS-2B cells to construct a differential circRNA expression profile.

    Article Title: RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus.
    Article Snippet: Corneal epithelium from db/db and WT mice was collected using a corneal epithelial scraper and sent to LC-BIO Co., Ltd. (Hangzhou, China) for RNA sequencing.

    Control:

    Article Title: A Novel Ah-miR2916-AhERF13-AhSUC3 Module Regulates Al Tolerance via Ethylene-Mediated Signaling in Peanut (Arachis hypogea L.).
    Article Snippet: Aluminum (Al) toxicity in acidic soils leads to a considerable reduction in crop yields.. MicroRNAs play essential roles in abiotic stress responses, but little is known of their role in the response of peanut (Arachis hypogea L.) to Al stress.. In this study, a novel Ah‐miR2916 (miR2916)–AhERF13–AhSUC3 module was found to be involved in the Al‐stress response via ethylene‐mediated signaling in peanut.

    RNA Sequencing:

    Article Title: A small RNA effector conserved in herbivore insects suppresses host plant defense by cross-kingdom gene silencing.
    Article Snippet: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record.. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article.. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

    Sequencing:

    Article Title: A small RNA effector conserved in herbivore insects suppresses host plant defense by cross-kingdom gene silencing.
    Article Snippet: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record.. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article.. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

    Article Title: Tetramycin B3: An Effective and Biological Nematicide for Bursaphelenchus xylophilus
    Article Snippet: .. They were then transported on dry ice to LC-BIO Co., Ltd., HangZhou, China, for transcriptome sequencing analysis [25]. ..

    Article Title: Spatial transcriptomics and multi-omics reveal relapse and resistance mechanisms of EndMT-derived CAFs mediated by TNC and FLNC in glioblastoma
    Article Snippet: .. All the Spatial Transcriptome Sequencing Data Analysis was performed using the OmicStudio tools created by LC-BIO Co., Ltd (HangZhou, China) at https://www.omicstudio.cn/spatial-infinity . ..

    Article Title: Tetramycin B3: An Effective and Biological Nematicide for Bursaphelenchus xylophilus
    Article Snippet: .. They were then transported on dry ice to LC-BIO Co., Ltd., HangZhou, China, for transcriptome sequencing analysis. ..



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    Image Search Results


    Investigations on SGMS2—related Cellular and Molecular Interactions in Hepatocellular Carcinoma. a Western blotting analysis of SGMS2 expression in THP—1 cells and differentiated macrophages. Each experiment was independently repeated three times. b , c Apoptosis levels of Huh7 tumor cells co—cultured with control macrophages and SGMS2—overexpressing macrophages were detected by flow cytometry (FCM). d Expression of SGMS2 in spatial transcriptomics sequencing data. e Abundance estimation of the CD56dimCD16highNR4A3high NK cell population by single—sample gene—set enrichment analysis (ssGSEA). f Multiplex immunofluorescence (mIF) images of SGMS2, CD68, CD16, CD56, and NR4A3 markers in 6 human HCC tissue samples. “Zoom macrophage” indicates the aggregation area of SGMS2—positive macrophages, and “Zoom NK cell” represents the CD56dimCD16highNR4A3high NK cells. The scale bar is 50 um or 20 um. g Scatter plots showing the density of CD56dimCD16highNR4A3high NK cells between patients with high and low infiltration of SGMS2—positive macrophages. Statistical analysis was performed using the Mann—Whitney U test. h Pearson correlation analysis of the density of CD56dimCD16highNR4A3high NK cells and the density of SGMS2—positive macrophages. i Kaplan—Meier analysis of OS, RFS, and early RFS in HCC patients with different infiltration densities of SGMS2—positive macrophages and CD56dimCD16highNR4A3high NK cells. Survival distributions were compared using the log—rank test. Statistical significance is indicated as follows: * P < 0.05, ** P < 0.01, *** P < 0.001; ns indicates no significant difference

    Journal: Journal of Translational Medicine

    Article Title: SGMS2+ macrophages enhance NR4A3hi NK cell infiltration to improve prognosis and PD-1 treatment efficacy in hepatocellular carcinoma

    doi: 10.1186/s12967-025-07040-x

    Figure Lengend Snippet: Investigations on SGMS2—related Cellular and Molecular Interactions in Hepatocellular Carcinoma. a Western blotting analysis of SGMS2 expression in THP—1 cells and differentiated macrophages. Each experiment was independently repeated three times. b , c Apoptosis levels of Huh7 tumor cells co—cultured with control macrophages and SGMS2—overexpressing macrophages were detected by flow cytometry (FCM). d Expression of SGMS2 in spatial transcriptomics sequencing data. e Abundance estimation of the CD56dimCD16highNR4A3high NK cell population by single—sample gene—set enrichment analysis (ssGSEA). f Multiplex immunofluorescence (mIF) images of SGMS2, CD68, CD16, CD56, and NR4A3 markers in 6 human HCC tissue samples. “Zoom macrophage” indicates the aggregation area of SGMS2—positive macrophages, and “Zoom NK cell” represents the CD56dimCD16highNR4A3high NK cells. The scale bar is 50 um or 20 um. g Scatter plots showing the density of CD56dimCD16highNR4A3high NK cells between patients with high and low infiltration of SGMS2—positive macrophages. Statistical analysis was performed using the Mann—Whitney U test. h Pearson correlation analysis of the density of CD56dimCD16highNR4A3high NK cells and the density of SGMS2—positive macrophages. i Kaplan—Meier analysis of OS, RFS, and early RFS in HCC patients with different infiltration densities of SGMS2—positive macrophages and CD56dimCD16highNR4A3high NK cells. Survival distributions were compared using the log—rank test. Statistical significance is indicated as follows: * P < 0.05, ** P < 0.01, *** P < 0.001; ns indicates no significant difference

    Article Snippet: Spatial transcriptomics sequencing data were obtained from http://lifeome.net/supp/livercancer-st/data.htm and analyzed using Seurat in R. Subsequently, SCTtransform normalization was performed.

    Techniques: Western Blot, Expressing, Cell Culture, Control, Flow Cytometry, Sequencing, Multiplex Assay, Immunofluorescence, MANN-WHITNEY