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customized whole-genome high-density microarrays  (Agendia BV)

 
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    Structured Review

    Agendia BV customized whole-genome high-density microarrays
    Available gene expression assays predictive of prognosis in early-stage CRC.
    Customized Whole Genome High Density Microarrays, supplied by Agendia BV, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/snp+microarray+analysis+high-density+snp+array/44k+full+genome+microarray/pmc10216373-0-22-20
    Average 90 stars, based on 1 article reviews
    customized whole-genome high-density microarrays - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Principles of Molecular Utility for CMS Classification in Colorectal Cancer Management"

    Article Title: Principles of Molecular Utility for CMS Classification in Colorectal Cancer Management

    Journal: Cancers

    doi: 10.3390/cancers15102746

    Available gene expression assays predictive of prognosis in early-stage CRC.
    Figure Legend Snippet: Available gene expression assays predictive of prognosis in early-stage CRC.

    Techniques Used: Gene Expression, Expressing, Formalin-fixed Paraffin-Embedded, Amplification, Microarray, Derivative Assay

    Related Articles

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    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: Biomarker analyses were performed on pre-treatment biopsies, which included the Agendia 44 K full-genome microarray and reverse-phase protein array (RPPA, performed by author EP at George Mason University).

    Article Title: Neoadjuvant trebananib plus paclitaxel-based chemotherapy for stage II/III breast cancer in the adaptively randomized I-SPY2 trial — Efficacy and biomarker discovery
    Article Snippet: The Agendia 44K full-genome microarray data were generated from pretreatment biopsies as described previously (24).

    Article Title: Principles of Molecular Utility for CMS Classification in Colorectal Cancer Management
    Article Snippet: ColoPrint colon cancer recurrence assay , Agendia, Inc. , 18-gene expression profile , Fresh tissue or fresh, frozen tissue , Agendia customized whole-genome high-density microarrays , Not FDA approved , [ , , ] .

    Article Title: Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer
    Article Snippet: Biomarker analyses were performed using Agendia 44 K full-genome microarrays assayed on biopsies at the pre-treatment time point for ganetespib and control population.

    Diagnostic Assay:

    Article Title: BluePrint breast cancer molecular subtyping recognizes single and dual subtype tumors with implications for therapeutic guidance.
    Article Snippet: Microarray processing was performed following standard procedure at Agendia [7] (Supplementary methods). .. Agendia’s customized diagnostic arrays were either a targeted array or a full genome array, as previously described [7, 13, 16]. ..

    Isolation:

    Article Title: IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women
    Article Snippet: Estradiol measurements were performed using a second-generation Cobas Estradiol immunoassay, and run on a Cobas 6000 device from Roche Diagnostics, following the standard manufacturer’s instructions. .. RNA was isolated and hybridized to a custom full genome array by Agendia as described previously . .. RNA was isolated from FFPE sections from using the Qiagen RNeasy FFPE kit.

    Gene Expression:

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. After the participant consents to be screened, a core biopsy will be performed, and sections will be sent to Agendia for MammaPrint score and TargetPrint HER2 gene expression assay using the Agendia 44K full genome microarray (MammaPrint 44K Array Low and High scores are determined per FDA label for the cleared MammaPrint device). ..

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. Qualified, pre-specified biomarkers evaluated included MammaPrint and TargetPrint HER2 gene expression arrays using the 44 K full genome microarray (Agendia) , HER2 quantitative protein expression, HER2 phosphorylation (Y1248), and EGFR phosphorylation (Y1173) by RPPA. ..

    Microarray:

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. After the participant consents to be screened, a core biopsy will be performed, and sections will be sent to Agendia for MammaPrint score and TargetPrint HER2 gene expression assay using the Agendia 44K full genome microarray (MammaPrint 44K Array Low and High scores are determined per FDA label for the cleared MammaPrint device). ..

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. Qualified, pre-specified biomarkers evaluated included MammaPrint and TargetPrint HER2 gene expression arrays using the 44 K full genome microarray (Agendia) , HER2 quantitative protein expression, HER2 phosphorylation (Y1248), and EGFR phosphorylation (Y1173) by RPPA. ..

    Expressing:

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. Qualified, pre-specified biomarkers evaluated included MammaPrint and TargetPrint HER2 gene expression arrays using the 44 K full genome microarray (Agendia) , HER2 quantitative protein expression, HER2 phosphorylation (Y1248), and EGFR phosphorylation (Y1173) by RPPA. ..

    Phospho-proteomics:

    Article Title: Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2 + breast cancer in the adaptively randomized I-SPY2 trial
    Article Snippet: .. Qualified, pre-specified biomarkers evaluated included MammaPrint and TargetPrint HER2 gene expression arrays using the 44 K full genome microarray (Agendia) , HER2 quantitative protein expression, HER2 phosphorylation (Y1248), and EGFR phosphorylation (Y1173) by RPPA. ..



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