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duvelisib  (Selleck Chemicals)


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    Structured Review

    Selleck Chemicals duvelisib
    Duvelisib, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sigma+plot+program+14+5/KD025/pmc09127801-155-15-27
    Average 93 stars, based on 22 article reviews
    duvelisib - by Bioz Stars, 2026-10
    93/100 stars

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    other:

    Article Title: Rho-kinase inhibition reduces subretinal fibrosis.
    Article Snippet: Fasudil (LKT-F0275; Biomol, St. Paul, MN, USA) and belumosudil (SLx-2119, KD-025; S7936; Selleck Chemicals, Houston, USA) were used as ROCK inhibitors.

    Article Title: Rho-kinase inhibition reduces subretinal fibrosis
    Article Snippet: Fasudil (LKT-F0275; Biomol, St. Paul, MN, USA) and belumosudil (SLx-2119, KD-025; S7936; Selleck Chemicals, Houston, USA) were used as ROCK inhibitors.

    Article Title: Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity
    Article Snippet: KD025 (Cat# S7936), 6-aminonicatinimide (Cat# S9783), Palbociclib(Cat# S4482), CB-839(Cat# S7655), Amlexanox (Cat# S3648), IM156(Cat# S9604), Metformin(Cat# S1950), and Phenformin(Cat# S2542) were all purchased from Selleck Chemicals (Houston, TX).

    Migration:

    Article Title: Rho kinase 2 promotes epithelial-mesenchymal transition and proliferation in human prostate cancer PC-3 cells
    Article Snippet: Protein expression levels were normalized using an anti-β-actin antibody (1:5000 dilution; A5316, MilliporeSigma, Burlington, USA). .. Cell growth, proliferation, and migration assays were performed as described previously.12,13 In brief, cells (3 × 104 cells/well) were exposed to culture medium containing vehicle (0.1 % DMSO) or KD025 (Selleck Chemicals, Houston, USA) for 48 h. Cell growth and proliferation were assessed using the Cell Counting Kit-8 (Dojindo Laboratories, Kumamoto, Japan) and Cell Proliferation ELISA, BrdU (Roche Diagnostics, Basel, Switzerland), respectively. .. For migration assay, cells (5.0 × 104 cells/well) in a 12-well Transwell plate (#3428, Corning, Corning, USA) were exposed to culture medium including vehicle or KD025 in the lower chamber for 24 h.

    CCK-8 Assay:

    Article Title: Rho kinase 2 promotes epithelial-mesenchymal transition and proliferation in human prostate cancer PC-3 cells
    Article Snippet: Protein expression levels were normalized using an anti-β-actin antibody (1:5000 dilution; A5316, MilliporeSigma, Burlington, USA). .. Cell growth, proliferation, and migration assays were performed as described previously.12,13 In brief, cells (3 × 104 cells/well) were exposed to culture medium containing vehicle (0.1 % DMSO) or KD025 (Selleck Chemicals, Houston, USA) for 48 h. Cell growth and proliferation were assessed using the Cell Counting Kit-8 (Dojindo Laboratories, Kumamoto, Japan) and Cell Proliferation ELISA, BrdU (Roche Diagnostics, Basel, Switzerland), respectively. .. For migration assay, cells (5.0 × 104 cells/well) in a 12-well Transwell plate (#3428, Corning, Corning, USA) were exposed to culture medium including vehicle or KD025 in the lower chamber for 24 h.

    Enzyme-linked Immunosorbent Assay:

    Article Title: Rho kinase 2 promotes epithelial-mesenchymal transition and proliferation in human prostate cancer PC-3 cells
    Article Snippet: Protein expression levels were normalized using an anti-β-actin antibody (1:5000 dilution; A5316, MilliporeSigma, Burlington, USA). .. Cell growth, proliferation, and migration assays were performed as described previously.12,13 In brief, cells (3 × 104 cells/well) were exposed to culture medium containing vehicle (0.1 % DMSO) or KD025 (Selleck Chemicals, Houston, USA) for 48 h. Cell growth and proliferation were assessed using the Cell Counting Kit-8 (Dojindo Laboratories, Kumamoto, Japan) and Cell Proliferation ELISA, BrdU (Roche Diagnostics, Basel, Switzerland), respectively. .. For migration assay, cells (5.0 × 104 cells/well) in a 12-well Transwell plate (#3428, Corning, Corning, USA) were exposed to culture medium including vehicle or KD025 in the lower chamber for 24 h.



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