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microarray for messenger rna (mrna)  (Pathwork Diagnostics Inc)

 
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    Structured Review

    Pathwork Diagnostics Inc microarray for messenger rna (mrna)
    Microarray For Messenger Rna (Mrna), supplied by Pathwork Diagnostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna+microarray/microarray+for+messenger+rna++mrna+/pmc08457440-67-6-25
    Average 90 stars, based on 1 article reviews
    microarray for messenger rna (mrna) - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Expressing:

    Article Title: Cancers of unknown primary origin: current perspectives and future therapeutic strategies
    Article Snippet: There are currently several commercial tests available with gene expression-based assays that classify tumors of unknown or uncertain origin: Pathwork [microarray for messenger RNA (mRNA)], Rosetta Genomics and Prometheus (RT-PCR for microRNA), and bioTheranostics (RT-PCR for mRNA).

    Article Title: A Systematic Review of Cancer of Unknown Primary in the Head and Neck Region
    Article Snippet: There are present commercial tests with gene expression-based assays that allow diagnosis of tumors of unknown or uncertain origin such as biotheranostics (RT-PCR for mRNA), Pathwork [microarray for messenger RNA (mRNA)] and Rosetta Genomics and Prometheus (RT-PCR for microRNA).

    Biomarker Discovery:

    Article Title: Cancers of unknown primary origin: current perspectives and future therapeutic strategies
    Article Snippet: There are currently several commercial tests available with gene expression-based assays that classify tumors of unknown or uncertain origin: Pathwork [microarray for messenger RNA (mRNA)], Rosetta Genomics and Prometheus (RT-PCR for microRNA), and bioTheranostics (RT-PCR for mRNA).

    Article Title: A Systematic Review of Cancer of Unknown Primary in the Head and Neck Region
    Article Snippet: There are present commercial tests with gene expression-based assays that allow diagnosis of tumors of unknown or uncertain origin such as biotheranostics (RT-PCR for mRNA), Pathwork [microarray for messenger RNA (mRNA)] and Rosetta Genomics and Prometheus (RT-PCR for microRNA).

    Microarray:

    Article Title: Cancers of unknown primary origin: current perspectives and future therapeutic strategies
    Article Snippet: There are currently several commercial tests available with gene expression-based assays that classify tumors of unknown or uncertain origin: Pathwork [microarray for messenger RNA (mRNA)], Rosetta Genomics and Prometheus (RT-PCR for microRNA), and bioTheranostics (RT-PCR for mRNA).

    Article Title: A Systematic Review of Cancer of Unknown Primary in the Head and Neck Region
    Article Snippet: There are present commercial tests with gene expression-based assays that allow diagnosis of tumors of unknown or uncertain origin such as biotheranostics (RT-PCR for mRNA), Pathwork [microarray for messenger RNA (mRNA)] and Rosetta Genomics and Prometheus (RT-PCR for microRNA).



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    Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA <t>microarray.</t> Volcano plots showing the differentially expressed <t>small</t> <t>RNA</t> species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived <t>small</t> <t>RNAs</t> (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.
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    Image Search Results


    Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA microarray. Volcano plots showing the differentially expressed small RNA species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived small RNAs (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.

    Journal: bioRxiv

    Article Title: Genetic inactivation of the Translin/Trax RNase activity alters small RNAs including miRNAs, disrupts gene expression and impairs distinct forms of hippocampal synaptic plasticity and memory

    doi: 10.1101/2025.07.10.663777

    Figure Lengend Snippet: Volcano plots showing the mature miRNAs differentially expressed in the TraxE126A mutants compared to wildtype littermates as identified by (A) miRNA sequencing and (B) miRNA microarray. Volcano plots showing the differentially expressed small RNA species identified using microarray analysis including (C) Precursor miRNAs (pre-miRNAs), (D) Small nucleolar RNAs (snoRNAs), (E) mature tRNAs and (F) tRNA-derived small RNAs (tsRNAs). In all the plots, the upregulated and downregulated miRNAs (false discovery rate, FDR <0.050 and log 2 fold change ≥0.200) are highlighted in red and blue, respectively. (TraxE126A, n=4; WT, n=5, all males). Largest changes were seen in tsRNA levels (majority are 5’-fragments) and mature miRNAs.

    Article Snippet: The labeled RNA species are then hybridized onto Arraystar Small RNA Expression Microarray (8×15K format), scanned by an Agilent G2505C scanner followed by data processing and analysis.

    Techniques: Sequencing, Microarray, Derivative Assay

    (A) Venn diagram showing the overlap between mature miRNAs identified using miRNA sequencing and microarray analysis (with FDR<0.050 and log 2 fold change ≥0.200). A total of 12 miRNAs (10 upregulated and 2 downregulated) were found to be common and were used for target prediction using miRDB database. (B) An upset plot showing the shared and unique predicted mRNA target profiles in the miRDB database for the 12 common miRNAs. Only targets with miRDB Target Score ≥60 are included. (C) Top 15 KEGG pathways and (D) Gene Ontology (GO) Biological Process terms from the functional enrichment analysis of the predicted targets of the 12 common miRNAs performed using DAVID database.

    Journal: bioRxiv

    Article Title: Genetic inactivation of the Translin/Trax RNase activity alters small RNAs including miRNAs, disrupts gene expression and impairs distinct forms of hippocampal synaptic plasticity and memory

    doi: 10.1101/2025.07.10.663777

    Figure Lengend Snippet: (A) Venn diagram showing the overlap between mature miRNAs identified using miRNA sequencing and microarray analysis (with FDR<0.050 and log 2 fold change ≥0.200). A total of 12 miRNAs (10 upregulated and 2 downregulated) were found to be common and were used for target prediction using miRDB database. (B) An upset plot showing the shared and unique predicted mRNA target profiles in the miRDB database for the 12 common miRNAs. Only targets with miRDB Target Score ≥60 are included. (C) Top 15 KEGG pathways and (D) Gene Ontology (GO) Biological Process terms from the functional enrichment analysis of the predicted targets of the 12 common miRNAs performed using DAVID database.

    Article Snippet: The labeled RNA species are then hybridized onto Arraystar Small RNA Expression Microarray (8×15K format), scanned by an Agilent G2505C scanner followed by data processing and analysis.

    Techniques: Sequencing, Microarray, Functional Assay