Review



polyhexanide (phmb  (Biosynth Carbosynth)


Bioz Verified Symbol Biosynth Carbosynth is a verified supplier
Bioz Manufacturer Symbol Biosynth Carbosynth manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 90

    Structured Review

    Biosynth Carbosynth polyhexanide (phmb
    The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.
    Polyhexanide (Phmb, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/phmb+hydrochloride/pmc08780725-384-6-8
    Average 90 stars, based on 1 article reviews
    polyhexanide (phmb - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters"

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters

    Journal: Pathogens

    doi: 10.3390/pathogens11010042

    The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.
    Figure Legend Snippet: The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.

    Techniques Used: Concentration Assay

    Comparison of the effectiveness of selected compounds in the eradication of K. pneumoniae clinical strain K81 biofilm from the catheter surface under flow conditions. C+, control of growth; H 2 O, sterile water; PHMB, polyhexanide; OCT, octenidine; BET, betaine; SAP, saponin; P-ETOH, phenoxyethanol. Statistically significant differences are marked with asterisks.
    Figure Legend Snippet: Comparison of the effectiveness of selected compounds in the eradication of K. pneumoniae clinical strain K81 biofilm from the catheter surface under flow conditions. C+, control of growth; H 2 O, sterile water; PHMB, polyhexanide; OCT, octenidine; BET, betaine; SAP, saponin; P-ETOH, phenoxyethanol. Statistically significant differences are marked with asterisks.

    Techniques Used: Comparison, Control, Sterility

    Related Articles

    Comparison:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Concentration Assay:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Membrane:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Filtration:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Inhibition:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Diffusion-based Assay:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Control:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Sterility:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Activity Assay:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Chick Chorioallantoic Membrane Assay:

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.

    Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters
    Article Snippet: The antimicrobial activity of the following compounds was determined in AUMg on polystyrene microtiter plates (Sarstedt, Blizne Laszczynskiego, Poland): Ciprofloxacin (CIPRO) (Merck, Darmstadt, Germany), CAMEL (CAM) (Lipopharm, Gdansk, Poland), Citropin 1.1 (CIT) (Lipopharm, Gdansk, Poland), Saponin (SAP) (Merck, Darmstadt, Germany), Betaine (BET) (Merck, Darmstadt, Germany), Chlorhexidine (CHX) (Fagron Pharma Cosmetics, Rotterdam, The Netherlands), Octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India), Polyhexanide (PHMB) (Carbosynth Ltd., Compton, Newbery, UK).

    Article Title: Antiseptic management of critical wounds: differential bacterial response upon exposure to antiseptics and first insights into antiseptic/phage interactions - experimental studies
    Article Snippet: Assessment of growth dynamics under reduced antiseptic concentrations The antiseptic products used were polyhexamethylene biguanide hydrochloride (in short: polyhexanide) - 20% aqueous solution (Biosynth, Switzerland) and octenidine dihydrochloride (in short: octenidine) 98% (Thermo Scientific, USA).

    Article Title: Sterilized Polyhexanide-Releasing Chitosan Membranes with Potential for Use in Antimicrobial Wound Dressings.
    Article Snippet: Discs with a diameter of 1.9 cm were placed in 15 mL Falcon tubes containing 5 mL of PHMB solutions (PHMB hydrochloride, ≥94%; Biosynth Carbosynth, Compton, UK) with Membranes 2023, 13, 877 5 of 25 concentrations of 0.1 mg/mL, 1 mg/mL, 2 mg/mL and 5 mg/mL in PBS.



    Similar Products

    86
    Beijing Chemical Works polyhexamethylene biguanide hydrochloride phmb
    Polyhexamethylene Biguanide Hydrochloride Phmb, supplied by Beijing Chemical Works, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/biguanide+hydrochloride+phmb+polyhexamethylene/10__1002_slash_app__70705-29-0-7
    Average 86 stars, based on 1 article reviews
    polyhexamethylene biguanide hydrochloride phmb - by Bioz Stars, 2026-10
    86/100 stars
      Buy from Supplier

    86
    B. Braun polyhexanide phmb
    Polyhexanide Phmb, supplied by B. Braun, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/phmb+polyhexanide/pm41284087-174-22-25
    Average 86 stars, based on 1 article reviews
    polyhexanide phmb - by Bioz Stars, 2026-10
    86/100 stars
      Buy from Supplier

    86
    Organogenesis Inc polyhexamethylene biguanide phmb antimicrobial barrier
    Polyhexamethylene Biguanide Phmb Antimicrobial Barrier, supplied by Organogenesis Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/antimicrobial+barrier+biguanide+phmb+polyhexamethylene/pm40906635-29-59-67
    Average 86 stars, based on 1 article reviews
    polyhexamethylene biguanide phmb antimicrobial barrier - by Bioz Stars, 2026-10
    86/100 stars
      Buy from Supplier

    93
    Biosynth Carbosynth phmb
    Phmb, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/Polyhexamethylene+biguanide+hydrochloride+-+Solid/pmc11596435-53-33-34
    Average 93 stars, based on 1 article reviews
    phmb - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    BOC Sciences polyhexamethylene biguanide phmb
    Polyhexamethylene Biguanide Phmb, supplied by BOC Sciences, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/PHMG/pm38060008-27-7-13
    Average 93 stars, based on 1 article reviews
    polyhexamethylene biguanide phmb - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    Biosynth Carbosynth polyhexamethylenebiguanide hydrochloride phmb
    Polyhexamethylenebiguanide Hydrochloride Phmb, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/Polyhexamethylene+biguanide+hydrochloride+-+Solid/10__1016_slash_j__colsurfa__2023__131906-51-0-6
    Average 93 stars, based on 1 article reviews
    polyhexamethylenebiguanide hydrochloride phmb - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    93
    Biosynth Carbosynth polyhexamethylene biguanide phmb
    Chemical structure of <t>polyhexamethylene</t> <t>biguanide</t> hydrochloride <t>(PHMB).</t>
    Polyhexamethylene Biguanide Phmb, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyhexanide+phmb/Polyhexamethylene+biguanide+hydrochloride+-+Solid/pmc10490332-69-0-6
    Average 93 stars, based on 1 article reviews
    polyhexamethylene biguanide phmb - by Bioz Stars, 2026-10
    93/100 stars
      Buy from Supplier

    Image Search Results


    Chemical structure of polyhexamethylene biguanide hydrochloride (PHMB).

    Journal: Polymers

    Article Title: Surface-Modified Carboxylated Cellulose Nanofiber Hydrogels for Prolonged Release of Polyhexamethylene Biguanide Hydrochloride (PHMB) for Antimicrobial Applications

    doi: 10.3390/polym15173572

    Figure Lengend Snippet: Chemical structure of polyhexamethylene biguanide hydrochloride (PHMB).

    Article Snippet: Polyhexamethylene biguanide (PHMB) was purchased from Carbosynth Ltd., Compton, UK.

    Techniques: