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cytochip isca 8 × 60 k v2.0 oligonusleotide array  (BlueGnome Limited)

 
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    BlueGnome Limited cytochip isca 8 × 60 k v2.0 oligonusleotide array
    Cytochip Isca 8 × 60 K V2.0 Oligonusleotide Array, supplied by BlueGnome Limited, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/oligonucleotide+array/cytochip++isca+8%C3%9760k+v2+0+oligonucleotide+array++ncb136+hg18+137/pmc03335511-30-9-12
    Average 90 stars, based on 1 article reviews
    cytochip isca 8 × 60 k v2.0 oligonusleotide array - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: Chromosome 22q12.1 microdeletions: confirmation of the MN1 gene as a candidate gene for cleft palate
    Article Snippet: Molecular karyotyping was performed by means of the BlueGnome ISCA 8 × 60 k OligoArray v2.0 and analyzed with Bluefuse Multi software (BlueGnome Ltd, Cambridge, UK).

    Article Title: Retinal and optic nerve changes in microcephaly
    Article Snippet: All affected individuals had a standard karyotyping (G banding) or microarray investigation using the ISCA 8 × 60 k v2 array (Agilent, Santa Clara, CA; or BlueGnome, Cambridge, UK).

    Article Title: CNVs affecting cancer predisposing genes (CPGs) detected as incidental findings in routine germline diagnostic chromosomal microarray (CMA) testing.
    Article Snippet: CNV detection using the Bluegnome 8×60k v2.0 (ISCA) design oligonucleotide array was carried out with a minimum three probe inclusion using Log2 ratio thresholds of ±0.3.

    Article Title: Xq21.1q21.31 Duplication in Two Male Siblings
    Article Snippet: Array CGH analysis of the proband and his brother was performed using the BlueGnome 8 × 60K v2.0 ISCA platform, with probes mapped to the GRCh37 (hg19) human genome assembly.

    Article Title: Partial deletion of TCF4 in three generation family with non-syndromic intellectual disability, without features of Pitt-Hopkins syndrome.
    Article Snippet: Mutations in TCF4 (basic helix-loop-helix transcription factor 4), a gene with complex organization and multiple transcription initiation sites, are usually associated with Pitt-Hopkins syndrome (PTHS).. However, a translocation encompassing the 50 end of TCF4 and several point mutations have been linked to non-syndromic intellectual disability (NSID).. Here we describe a family with autosomal dominantly inherited NSID in seven relatives with a partial deletion of TCF4, disrupting the 50 end of the gene, predicted to result in the reduction of the number of mRNAs that can be produced by alternative transcription initiation.

    Article Title: An alternative to array-based diagnostics: a prospectively recruited cohort, comparing arrayCGH to next-generation sequencing to evaluate foetal structural abnormalities.
    Article Snippet: Diagnostic quantitative fluorescence (QF)-PCR was performed to exclude aneuploidy of chromosomes 13, 18 and 21, triploidy and monosomy X. Array-CGH was subsequently processed on a BlueGnome ISCA 8 60 k oligoarray, following the manufacturer’s protocols (Illumina Inc, San Diego, CA, USA).

    Article Title: The effect of polyhydramnios degree on chromosomal microarray results: a retrospective cohort analysis of 742 singleton pregnancies.
    Article Snippet: Purpose To analyze the risk for clinically significant microarray aberrations in pregnancies with polyhydramnios.. Methods Data from all chromosomal microarray analyses (CMA) performed due to polyhydramnios between January 2013 and December 2019 were retrospectively obtained from the Ministry of Health Database.. The rate of clinically significant (pathogenic and likely pathogenic) CMA findings in isolated and non-isolated polyhydramnios cohorts was compared to a local control group of 5541 fetuses with normal ultrasound, in which 78 (1.4%) abnormal results were demonstrated.

    Hybridization:

    Article Title: Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management
    Article Snippet: .. After the recent description of germline Xq26.3 microduplication in young children with acrogigantism , likely due to the duplicated GPR101 gene within this region, we tested the patient's leukocyte-, saliva-, and buccal cell-derived DNA using a comparative genomic hybridization array (BlueGnome CytoChip ISCA 8 × 60k v2.0; Illumina) and copy number variation droplet digital PCR for GPR101 (Taqman assays Hs01818174_cn and Hs01730605_cn; Life Technologies) without evidence of Xq26.3 microduplications or GPR101 duplication, although his clinical phenotype was identical to the previously published patients. ..

    Digital PCR:

    Article Title: Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management
    Article Snippet: .. After the recent description of germline Xq26.3 microduplication in young children with acrogigantism , likely due to the duplicated GPR101 gene within this region, we tested the patient's leukocyte-, saliva-, and buccal cell-derived DNA using a comparative genomic hybridization array (BlueGnome CytoChip ISCA 8 × 60k v2.0; Illumina) and copy number variation droplet digital PCR for GPR101 (Taqman assays Hs01818174_cn and Hs01730605_cn; Life Technologies) without evidence of Xq26.3 microduplications or GPR101 duplication, although his clinical phenotype was identical to the previously published patients. ..



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