histological analysis tissue microarray (OriGene)
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Histological Analysis Tissue Microarray, supplied by OriGene, used in various techniques. Bioz Stars score: 91/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/normal+tissue+microarrays/Normal+Tissue+Microarray/pmc04845097-467-2-9
Average 91 stars, based on 9 article reviews
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1) Product Images from "Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA-Damage Responses and Correlates With Tumorigenesis"
Article Title: Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA-Damage Responses and Correlates With Tumorigenesis
Journal: Cell reports
doi: 10.1016/j.celrep.2015.12.029
Figure Legend Snippet: (A) Immunoblot of STING in hTERT fibroblasts, normal human colon epithelial (FHC) and a series of human colon cancer cell lines. (B) ELISA analysis of human Interferon β production in the media of cells (same as A) transfected with 3μg/ml polyIC or dsDNA90 or mock transfected for 16 hours. (C) qPCR analysis of human CXCL10 expression in cells (same as A) transfected with 3μg/ml dsDNA90 or mock transfected for 3 hours. (D) qPCR analysis of human IL1B expression in cells same as C. Data is representative of at least two independent experiments. Error bars indicate s.d. *, p<0.05; **, p<0.01; ***, p<0.001; Student’s t-test. (E) Microarray analysis of gene expression in indicated normal and colon cancer cells mock transfected or transfected with 3μg/ml dsDNA90 for 3 hours. Highest variable genes are shown. Rows represent individual genes; columns represent individual samples. Pseudo-colors indicate transcript levels below (green), equal to (black), or above (red) the mean. Scale represents the intensity of gene expression (log10 scale ranges between −3 and 3). (F) Fold change values of highest variable genes shown in E. See also Figure S1 and S2.
Techniques Used: Western Blot, Enzyme-linked Immunosorbent Assay, Transfection, Expressing, Microarray, Gene Expression
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