Review




Structured Review

InterPro Inc clustal omega61 multiple sequence alignment
(A) The mature nisin peptide has thioether crosslinks between Cys and dehydroalanine (Dha) and dehydrobutyrine (Dhb) residues. (B) The sactipeptide subtilosin A is shown, highlighting the three thioether crosslinks. In its fully mature form, subtilosin A is circularized. The stereochemistry at the three attachment sites is shown in red. The sactipeptides are distinct from the lanthipeptides in that the thioether crosslinks are formed to the Cα of the peptide. (C) Sequence logo for the SCIFF peptides showing the conserved C-terminal sequence. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal <t>Omega61</t> multiple sequence alignment and visualized by Weblogo.62,63
Clustal Omega61 Multiple Sequence Alignment, supplied by InterPro Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multiple+sequence+alignment/clustal+omega61+multiple+sequence+alignment/pmc04829460-25-16-11
Average 90 stars, based on 1 article reviews
clustal omega61 multiple sequence alignment - by Bioz Stars, 2026-09
90/100 stars

Images

1) Product Images from "Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink"

Article Title: Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink

Journal: Biochemistry

doi: 10.1021/acs.biochem.6b00145

(A) The mature nisin peptide has thioether crosslinks between Cys and dehydroalanine (Dha) and dehydrobutyrine (Dhb) residues. (B) The sactipeptide subtilosin A is shown, highlighting the three thioether crosslinks. In its fully mature form, subtilosin A is circularized. The stereochemistry at the three attachment sites is shown in red. The sactipeptides are distinct from the lanthipeptides in that the thioether crosslinks are formed to the Cα of the peptide. (C) Sequence logo for the SCIFF peptides showing the conserved C-terminal sequence. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega61 multiple sequence alignment and visualized by Weblogo.62,63
Figure Legend Snippet: (A) The mature nisin peptide has thioether crosslinks between Cys and dehydroalanine (Dha) and dehydrobutyrine (Dhb) residues. (B) The sactipeptide subtilosin A is shown, highlighting the three thioether crosslinks. In its fully mature form, subtilosin A is circularized. The stereochemistry at the three attachment sites is shown in red. The sactipeptides are distinct from the lanthipeptides in that the thioether crosslinks are formed to the Cα of the peptide. (C) Sequence logo for the SCIFF peptides showing the conserved C-terminal sequence. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega61 multiple sequence alignment and visualized by Weblogo.62,63

Techniques Used: Sequencing, Generated

Related Articles

Generated:

Article Title: Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink
Article Snippet: .. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega61 multiple sequence alignment and visualized by Weblogo.62,63. .. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega 61 multiple sequence alignment and visualized by Weblogo.

Sequencing:

Article Title: Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink
Article Snippet: .. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega61 multiple sequence alignment and visualized by Weblogo.62,63. .. The figure was generated by aligning 100 SCIFF sequences selected from Interpro family IPR023975 using the Clustal Omega 61 multiple sequence alignment and visualized by Weblogo.



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