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mouse genome-wide mirna microarray analysis  (Phalanx Biotech)

 
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    Structured Review

    Phalanx Biotech mouse genome-wide mirna microarray analysis
    Clustering of differentially expressed circulating <t>microRNAs</t> in the whole blood of C567BL/6 mice at 4, 8, and 24 h after cecal ligation and puncture (A) and subcutaneous bacteria injection with 1×10 8 E. coli. or S. aureus (B).
    Mouse Genome Wide Mirna Microarray Analysis, supplied by Phalanx Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mirna+microarray+data+analysis/mouse+genome+wide+mirna+microarray+analysis/pmc03813489-130-0-11
    Average 90 stars, based on 1 article reviews
    mouse genome-wide mirna microarray analysis - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture"

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0077936

    Clustering of differentially expressed circulating microRNAs in the whole blood of C567BL/6 mice at 4, 8, and 24 h after cecal ligation and puncture (A) and subcutaneous bacteria injection with 1×10 8 E. coli. or S. aureus (B).
    Figure Legend Snippet: Clustering of differentially expressed circulating microRNAs in the whole blood of C567BL/6 mice at 4, 8, and 24 h after cecal ligation and puncture (A) and subcutaneous bacteria injection with 1×10 8 E. coli. or S. aureus (B).

    Techniques Used: Ligation, Bacteria, Injection

    Venn diagram showing the common and specific up-regulated miRNAs in the cecal ligation and puncture experiment without and after subcutaneous injection of gram-negative or gram-positive bacteria.
    Figure Legend Snippet: Venn diagram showing the common and specific up-regulated miRNAs in the cecal ligation and puncture experiment without and after subcutaneous injection of gram-negative or gram-positive bacteria.

    Techniques Used: Ligation, Injection, Bacteria

    Related Articles

    Genome Wide:

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
    Article Snippet: Mouse genome-wide miRNA microarray analysis and statistical analysis was performed by Phalanx Biotech.

    Microarray:

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
    Article Snippet: Mouse genome-wide miRNA microarray analysis and statistical analysis was performed by Phalanx Biotech.

    Ligation:

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
    Article Snippet: Mouse genome-wide miRNA microarray analysis and statistical analysis was performed by Phalanx Biotech.

    Bacteria:

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
    Article Snippet: Mouse genome-wide miRNA microarray analysis and statistical analysis was performed by Phalanx Biotech.

    Injection:

    Article Title: Profiling Circulating MicroRNA Expression in Experimental Sepsis Using Cecal Ligation and Puncture
    Article Snippet: Mouse genome-wide miRNA microarray analysis and statistical analysis was performed by Phalanx Biotech.



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    Image Search Results


    (A)Volcano plot of miRNA expression in RV-HF vs RV-Ctrl. Blue dots, miRNAs that were differentially expressed at P<0.10. Labeled dots, miRNAs that were differentially expressed at a minimum 2-fold change in either direction (n=3 per group). (B)Heat maps, Venn diagram, and summary bar graph of differentially expressed miRNAs. Orange font, differentially expressed in RV-HF vs RV-Ctrl and in LV-HF vs LV-Ctrl but not statistically significantly different in RV-HF vs LV-HF. Blue font, differentially expressed in RV-HF vs RV-Ctrl and in RV-HF vs LV-HF, but not statistically significantly different in LV-HF vs LV-Ctrl. Purple font, differentially expressed across all three comparisons: LV-HF vs LV-Ctrl, RV-HF vs RV-Ctrl, and RV-HF vs LV-HF. *P<0.05 vs respective LV-HF/LV-Ctrl. (C)Quantitative RT-PCR analysis of miR-21 and miR-221 in ventricular tissue, n= 6 per group. *P<0.01 vs respective Ctrl; #P<0.01 vs LV HF. (D)Cyclic overstretch and/or aldosterone induced a marked increase in miR-21 (*P<0.01 vs unstimulated) and (E)miR-221 (*P<0.05 vs unstimulated) only in RV fibroblasts. (F)Inhibition of miR-21/−221 attenuated proliferation in RV but not LV fibroblasts. n= 4 per experimental condition. *P<0.05 vs respective LV, #P<0.05 vs RV without antimir, analyzed by ANOVA on Ranks.

    Journal: Circulation. Heart failure

    Article Title: Differential microRNA-21 and microRNA-221 upregulation in the biventricular failing heart reveals distinct stress responses of right versus left ventricular fibroblasts

    doi: 10.1161/CIRCHEARTFAILURE.119.006426

    Figure Lengend Snippet: (A)Volcano plot of miRNA expression in RV-HF vs RV-Ctrl. Blue dots, miRNAs that were differentially expressed at P<0.10. Labeled dots, miRNAs that were differentially expressed at a minimum 2-fold change in either direction (n=3 per group). (B)Heat maps, Venn diagram, and summary bar graph of differentially expressed miRNAs. Orange font, differentially expressed in RV-HF vs RV-Ctrl and in LV-HF vs LV-Ctrl but not statistically significantly different in RV-HF vs LV-HF. Blue font, differentially expressed in RV-HF vs RV-Ctrl and in RV-HF vs LV-HF, but not statistically significantly different in LV-HF vs LV-Ctrl. Purple font, differentially expressed across all three comparisons: LV-HF vs LV-Ctrl, RV-HF vs RV-Ctrl, and RV-HF vs LV-HF. *P<0.05 vs respective LV-HF/LV-Ctrl. (C)Quantitative RT-PCR analysis of miR-21 and miR-221 in ventricular tissue, n= 6 per group. *P<0.01 vs respective Ctrl; #P<0.01 vs LV HF. (D)Cyclic overstretch and/or aldosterone induced a marked increase in miR-21 (*P<0.01 vs unstimulated) and (E)miR-221 (*P<0.05 vs unstimulated) only in RV fibroblasts. (F)Inhibition of miR-21/−221 attenuated proliferation in RV but not LV fibroblasts. n= 4 per experimental condition. *P<0.05 vs respective LV, #P<0.05 vs RV without antimir, analyzed by ANOVA on Ranks.

    Article Snippet: miRNA microarray data was analyzed for differential miRNA expression between pre-specified groups (RV-HF vs. RV-Ctrl, LV-HF vs. LV-Ctrl, and RV-HF vs. LV-HF) by two-tailed Student’s t-test using GraphPad Software (Prism 7.0).

    Techniques: Expressing, Labeling, Quantitative RT-PCR, Inhibition