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human 660w-quad snp microarray platform  (INFINIUM Inc)

 
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    INFINIUM Inc human 660w-quad snp microarray platform
    Human 660w Quad Snp Microarray Platform, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+snp+genotype+data/660w+snp+array/pmc03280307-92-6-5
    Average 90 stars, based on 1 article reviews
    human 660w-quad snp microarray platform - by Bioz Stars, 2026-09
    90/100 stars

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    other:

    Article Title: An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians
    Article Snippet: 648 UC cases and 850 controls were genotyped using Infinium Human 660W-quad.

    Article Title: Changes in Refractive Error During Young Adulthood: The Effects of Longitudinal Screen Time, Ocular Sun Exposure, and Genetic Predisposition.
    Article Snippet: Samples from 1592 participants were analyzed in 2010 using an Infinium HD Human 660W-Quad BeadChip Array and those from an additional 310 participants were analyzed in 2013 using an Infinium OmniExpress-24 BeadChip Array.

    Article Title: An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians
    Article Snippet: Six of the 59 meta-analysis index SNPs were not present in the Infinium Human 660W-quad array used in this study ( ).


    Article Title: An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians
    Article Snippet: For replicating meta-analysis based associations, 648 cases and 850 controls were genotyped using Infinium Human 660W-quad.

    Article Title: Association of AFF3 Gene Polymorphism rs10865035 with Rheumatoid Arthritis: A Population-Based Case-Control Study on a Pakistani Cohort
    Article Snippet: They selected 42 candidate genes/loci (3 Asian and 39 European) and tested 603 SNPs, which were either index SNPs or were surrogate SNPs, using Infinium Human 660w-quad microarray methods for genotyping.

    GWAS:

    Article Title: Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism.
    Article Snippet: .. GWAS was conducted in the complete dataset of 212 incident VTE families genotyped using the Infinium 660W SNP array. ..

    Article Title: Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism.
    Article Snippet: .. In the past several years, numerousGWAS have confirmed established risk factors, such as FV, FGG, and the ABO locus, and yielded novel susceptibility genes for VTE in adults.7-11 Here we present the first GWAS on VTE in children using the Infinium 660W SNP array and a large collection of affected nuclear families comprising 212 parentchild trios. ..



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    Mapping of the CFTR locus in a nonconsanguineous CEPH family (Pedigree 3, see the section Methods), using variant data derived either ( A ) from exome sequencing or ( B ) from microarray SNP genotyping (Affymetrix SNP 6.0). Display of Chromosome 7 haplotypes was performed using Phaser [Carr et al., ]. In this display, blue and pink vertical bars denote the haplotypes inherited by the first affected offspring from the father and mother, respectively. The disease locus must be located in a region where all affected individuals share the same combination of maternal (pink) and paternal (blue) haplotypes as this first individual. This is denoted by a purple color in the central vertical bar (region of overlap between the affected paternal and maternal haplotypes). Unaffected offspring should be discordant with their affected siblings at the disease locus (i.e., no purple bar). In this example, the actual position of the CFTR gene is marked by a horizontal red line. It can be seen that the candidate region containing CFTR is considerably smaller in ( B ), due to the superior resolution and distribution of the microarray SNPs.

    Journal: Human Mutation

    Article Title: Rapid Detection of Rare Deleterious Variants by Next Generation Sequencing with Optional Microarray SNP Genotype Data

    doi: 10.1002/humu.22818

    Figure Lengend Snippet: Mapping of the CFTR locus in a nonconsanguineous CEPH family (Pedigree 3, see the section Methods), using variant data derived either ( A ) from exome sequencing or ( B ) from microarray SNP genotyping (Affymetrix SNP 6.0). Display of Chromosome 7 haplotypes was performed using Phaser [Carr et al., ]. In this display, blue and pink vertical bars denote the haplotypes inherited by the first affected offspring from the father and mother, respectively. The disease locus must be located in a region where all affected individuals share the same combination of maternal (pink) and paternal (blue) haplotypes as this first individual. This is denoted by a purple color in the central vertical bar (region of overlap between the affected paternal and maternal haplotypes). Unaffected offspring should be discordant with their affected siblings at the disease locus (i.e., no purple bar). In this example, the actual position of the CFTR gene is marked by a horizontal red line. It can be seen that the candidate region containing CFTR is considerably smaller in ( B ), due to the superior resolution and distribution of the microarray SNPs.

    Article Snippet: Exome variant data were only available for two affected siblings, while Affymetrix SNP 6.0 microarray SNP genotype data were available for a third affected sibling and two unaffected siblings.

    Techniques: Variant Assay, Derivative Assay, Sequencing, Microarray