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tissue microarray slides  (Akoya Biosciences)


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    Structured Review

    Akoya Biosciences tissue microarray slides
    Tissue Microarray Slides, supplied by Akoya Biosciences, used in various techniques. Bioz Stars score: 99/100, based on 5454 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+slide/PhenoImager+HT/pm41299174-1068-0-15
    Average 99 stars, based on 5454 article reviews
    tissue microarray slides - by Bioz Stars, 2026-10
    99/100 stars

    Images

    Related Articles

    Staining:

    Article Title: Natural Asp-tRNA Synthetase Fragment Targets Myofibroblasts to Abrogate Tissue Fibrosis.
    Article Snippet: Finally, slides were incubated with 1X Spectral DAPI (Akoya Biosciences) at room temperature for 20min. .. After staining, slides were airdried, coverslipped using the Leica CV5030 with ProLong Diamond Antifade Mountant (Invitrogen, #P36970) and scanned at 20X magnification using the Akoya Vectra Polaris / PhenoImager HT fluorescent slide scanner (Akoya Biosciences). .. LTBP-1 and Fc Duplex Immunofluorescence: All staining procedures were performed at iHisto, Inc. (Salem, MA) using a previously optimized manual staining procedure.

    Article Title: A CCL21 gene-modified dendritic cell vaccine combined with pembrolizumab in advanced non-small cell lung cancer: a phase I trial
    Article Snippet: The slides were then counterstained with Spectral DAPI (Akoya Biosciences) and mounted with ProLong Diamond antifade medium (Thermo Fisher Scientific). .. Stained slides were imaged using the Vectra Polaris imaging system (v1.0, Akoya Biosciences). .. Slide scans were then imported into HALO (v3.6, Indica Labs) for stitching, selecting regions of interest, cell segmentation, and signal quantification.

    Article Title: A multi-omics analysis of advanced triple-negative breast cancer identifies predictors to chemo-immunotherapy and on-treatment dynamics.
    Article Snippet: .. The mIF stained slides were scanned using the PhenoImager HT (Akoya Biosciences) with the MOTiF TM mode, allowing whole slide multispectral image acquisition. ..

    Software:

    Article Title: Persistent SARS-CoV-2 infection in SCID rats reflects immune vulnerability of the upper airway and trachea.
    Article Snippet: .. Images captured by Vectra Polaris (Akoya Biosciences) were analyzed using inForm software (Akoya Biosciences) to provide quantitative measure ments of the distance between infected and immune cells, the number of infected cells, and the ratio of immune cells to infected cells. ..

    Article Title: IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial
    Article Snippet: .. Finally, spectral DAPI (Akoya Bioscience) was added for 5min at room temperature, and the slides weremounted in X6 Immu-Mount (Fisher Scientific), then cured in the dark at room temperature for 1 h. Slides were scanned by the Perkin Elmer Vectra Polaris scanner (Akoya Bioscience) using PhenoImager HT 2.0 software. .. Digital image analysis was performed in HALO Image Analysis Platform version 3.6.4134 (Indica Labs) using the Highplex FL v4.2.14 module for cell segmentation, mark up, phenotyping and quantification.

    Article Title: A transient MXD4-dependent proliferative pause enables survival of brain micrometastases.
    Article Snippet: In total, six staining cycles utilizing different primary antibodies and TSA fluorophores were performed before counterstaining with DAPI (Sigma-Aldrich) and mounting in Fluoromount-G medium (SouthernBiotech) to finalize the staining. .. Whole slide scans of the sections were acquired using the PhenoImager HT instrument (Akoya Biosciences) and regions of interests (ROIs) were identified using Phenochart software (Akoya Biosciences). .. Multispectral images (MSIs) at ×200 magnification were captured, spectrally unmixed, and exported as multi-channel TIFF files using inForm software (Akoya Biosciences).

    Infection:

    Article Title: Persistent SARS-CoV-2 infection in SCID rats reflects immune vulnerability of the upper airway and trachea.
    Article Snippet: .. Images captured by Vectra Polaris (Akoya Biosciences) were analyzed using inForm software (Akoya Biosciences) to provide quantitative measure ments of the distance between infected and immune cells, the number of infected cells, and the ratio of immune cells to infected cells. ..

    Imaging:

    Article Title: A CCL21 gene-modified dendritic cell vaccine combined with pembrolizumab in advanced non-small cell lung cancer: a phase I trial
    Article Snippet: The slides were then counterstained with Spectral DAPI (Akoya Biosciences) and mounted with ProLong Diamond antifade medium (Thermo Fisher Scientific). .. Stained slides were imaged using the Vectra Polaris imaging system (v1.0, Akoya Biosciences). .. Slide scans were then imported into HALO (v3.6, Indica Labs) for stitching, selecting regions of interest, cell segmentation, and signal quantification.

    Article Title: Macrophage-derived MMP14 fosters immunosuppressive tumor microenvironment by regulating soluble semaphorin 4D
    Article Snippet: All the slides were counterstained with Cell Death Discovery spectral DAPI (Akoya Biosciences) and mounted with an anti-fade fluorescence mounting medium (ab104135, Abcam). .. Multichannel imaging was performed using the Vectra Polaris Imaging System (Akoya Biosciences). ..



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    Grace Bio-Labs custom nitrocellulose coated microarray slides
    Mean <t>microarray</t> antigen spot intensities from TB-free badger serum samples at two time points following experimental infection. White bars represent TB-free sera; gray bars represent TB-infected sera collected at ( a ) 8 weeks and ( b ) 12–13 weeks post-infection. Mean microarray spot intensities (log 2 -normalized) are shown with 95% confidence interval error bars. Paired-sample t -tests were carried out comparing pre- and post-infection mean spot intensities. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown. Significance levels: ns: P ≥ 0.05; *: P < 0.05; **: P < 0.01; and ***: P < 0.001.
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    Mean <t>microarray</t> antigen spot intensities from TB-free badger serum samples at two time points following experimental infection. White bars represent TB-free sera; gray bars represent TB-infected sera collected at ( a ) 8 weeks and ( b ) 12–13 weeks post-infection. Mean microarray spot intensities (log 2 -normalized) are shown with 95% confidence interval error bars. Paired-sample t -tests were carried out comparing pre- and post-infection mean spot intensities. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown. Significance levels: ns: P ≥ 0.05; *: P < 0.05; **: P < 0.01; and ***: P < 0.001.
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    Akoya Biosciences tissue microarray slides
    Mean <t>microarray</t> antigen spot intensities from TB-free badger serum samples at two time points following experimental infection. White bars represent TB-free sera; gray bars represent TB-infected sera collected at ( a ) 8 weeks and ( b ) 12–13 weeks post-infection. Mean microarray spot intensities (log 2 -normalized) are shown with 95% confidence interval error bars. Paired-sample t -tests were carried out comparing pre- and post-infection mean spot intensities. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown. Significance levels: ns: P ≥ 0.05; *: P < 0.05; **: P < 0.01; and ***: P < 0.001.
    Tissue Microarray Slides, supplied by Akoya Biosciences, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Mean microarray antigen spot intensities from TB-free badger serum samples at two time points following experimental infection. White bars represent TB-free sera; gray bars represent TB-infected sera collected at ( a ) 8 weeks and ( b ) 12–13 weeks post-infection. Mean microarray spot intensities (log 2 -normalized) are shown with 95% confidence interval error bars. Paired-sample t -tests were carried out comparing pre- and post-infection mean spot intensities. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown. Significance levels: ns: P ≥ 0.05; *: P < 0.05; **: P < 0.01; and ***: P < 0.001.

    Journal: Journal of Clinical Microbiology

    Article Title: Proteome microarray-guided identification of mycobacterial antigens and ELISA-based peptide mapping for improved serological detection of Mycobacterium bovis infection in European badgers

    doi: 10.1128/jcm.01260-25

    Figure Lengend Snippet: Mean microarray antigen spot intensities from TB-free badger serum samples at two time points following experimental infection. White bars represent TB-free sera; gray bars represent TB-infected sera collected at ( a ) 8 weeks and ( b ) 12–13 weeks post-infection. Mean microarray spot intensities (log 2 -normalized) are shown with 95% confidence interval error bars. Paired-sample t -tests were carried out comparing pre- and post-infection mean spot intensities. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown. Significance levels: ns: P ≥ 0.05; *: P < 0.05; **: P < 0.01; and ***: P < 0.001.

    Article Snippet: Translated proteins and IVTT controls were printed onto custom nitrocellulose-coated microarray slides (Grace Bio-Labs, Bend, OR, USA) using a GeneMachines OmniGrid Accent Microarray Printer.

    Techniques: Microarray, Infection, Comparison

    Mean microarray antigen spot intensities from TB-infected and BCG-vaccinated badger serum samples. Gray bars represent sera from TB-infected badgers collected 12–13 weeks after experimental infection; white bars represent sera from badgers that received ( a ) a single BCG vaccination or ( b ) two BCG vaccinations. Mean spot intensities (log₂-normalized) are shown with 95% confidence interval error bars. Independent-samples t -tests were used to compare antigen intensities between TB-infected and BCG-vaccinated groups. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown; ***: P < 0.001.

    Journal: Journal of Clinical Microbiology

    Article Title: Proteome microarray-guided identification of mycobacterial antigens and ELISA-based peptide mapping for improved serological detection of Mycobacterium bovis infection in European badgers

    doi: 10.1128/jcm.01260-25

    Figure Lengend Snippet: Mean microarray antigen spot intensities from TB-infected and BCG-vaccinated badger serum samples. Gray bars represent sera from TB-infected badgers collected 12–13 weeks after experimental infection; white bars represent sera from badgers that received ( a ) a single BCG vaccination or ( b ) two BCG vaccinations. Mean spot intensities (log₂-normalized) are shown with 95% confidence interval error bars. Independent-samples t -tests were used to compare antigen intensities between TB-infected and BCG-vaccinated groups. Antigens were ranked by BH-adjusted P -values, and the 10 most differential antigens (defined as those with the lowest BH-adjusted P -values) for each comparison group are shown; ***: P < 0.001.

    Article Snippet: Translated proteins and IVTT controls were printed onto custom nitrocellulose-coated microarray slides (Grace Bio-Labs, Bend, OR, USA) using a GeneMachines OmniGrid Accent Microarray Printer.

    Techniques: Microarray, Infection, Comparison