Clinical Proteomics:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Binding Assay:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Control:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Microarray:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Quantitative Dot Blot:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Hybridization:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Expressing:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
Clone Assay:Article Title: Method for detecting radiation exposure
Article Snippet: TABLE 3 Stress gene responses in γ-irradiated human myeloid cells Mean Green Transcript Image ID Microarraya Intensityb CIP1/WAF1 268652 42.0c 1121 ATF3 428248 11.3c 784 FAS 151767 9.5 1352 IAP-1 129632 9.3d 132 .RELB 52681 7.2d 1027 cyclin I 512391 6.9 974 RAB 52530 6.4 1688 GADD45 310141 5.8d 2230 FRA1 110503 4.8c 672 IL-8 328692 4.8 5307 CSF-1 124554 4.7 356 BCL3 236422 4.6c 584 MIP1α 153355 4.3 475 c-FOS 26474 4.2 1314 JUN-B 309477 4.2 1892 PC-1 52753 3.4c 343 CDC5 280376 3.4 1259 MRC OX-2 51363 3.4d 290 ERR1 470602 3.2 490 MDM2 147075 3.2d 328 Immunoglobulin J chain 161023 3.1 331 OX40 ligand 35326 3.1 310 DNA ligase III 470062 3.0 636 cytochrome p450 4A 120466 3.0 218 MEK1 486074 2.9 1885 TPK receptor UFO 112500 2.8 285 Retinoic acid gamma-1 471252 2.8 288 HPTP alpha 487130 2.8 282 MBP-1 291503 2.8c 206 SSAT 41452 2.7c 4160 BAK e 2.7c 341 MBP-2 23464 2.5 462 iL-TMP 243143 2.5d 383 MIP1beta 205633 2.5 352 N-RAS 284031 2.5 341 nucleotide binding protein 21420 2.5 394 mRNA CAP-R 48677 2.4 577 BCL-XL e 2.3c 313 ch-TOG 43060 0.53 9209 ERK 487417 0.51 9323 CDC2 346534 0.47 19501 SATB1 233194 0.46c 30364 SPI-B 295093 0.45 3747 ERF-1 48085 0.44 6935 MADP2 homolog 26541 0.43 20543 neuron-specific protein gene 28089 0.38 8098 TOPO II 248032 0.34c 37173 CDK RS2 359119 0.27 13935 RCH-1 28116 0.23c 24932 c-MYC 51699 0.12c 17913 aRatios of relative induction by γ-rays compared to basal levels in ML-1 cells. bFluorescence intensity of untreated control on the microarray. cMicroarray measurement confirmed by quantitative dot blot hybridization where expression varied by less than 2-fold. dQuantitation varied by more than 2-fold. eInserts for BAK (Chittenden et al., Nature 374: 733-6, 1995) and BCL-XL (Boise et al., Cell 74: 597-608, 1993) from clones other than Image Consortium ESTs.
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