rna expression profiling huex microarray (INFINIUM Inc)
90
Structured Review
INFINIUM Inc
rna expression profiling huex microarray
Rna Expression Profiling Huex Microarray, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+expression+profiling+datasets/pmc06855946-178-42-62?v=INFINIUM+Inc
Average 90 stars, based on 1 article reviews
Rna Expression Profiling Huex Microarray, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+expression+profiling+datasets/pmc06855946-178-42-62?v=INFINIUM+Inc
Average 90 stars, based on 1 article reviews
rna expression profiling huex microarray - by Bioz Stars,
2026-08
90/100 stars
Images
1) Product Images from "Differences in Genomic Profiles and Outcomes Between Thoracic and Adrenal Neuroblastoma"
Article Title: Differences in Genomic Profiles and Outcomes Between Thoracic and Adrenal Neuroblastoma
Journal: JNCI Journal of the National Cancer Institute
doi: 10.1093/jnci/djz027
Figure Legend Snippet: Adrenal vs thoracic tumor copy number association analysis. A) Meta-analysis by nonoverlapping 1-Mb tiles. The y-axis reflects an inverse variance-weighted meta-analysis across four datasets—single nucleotide polymorphism (SNP) microarray, whole genome sequencing, whole exome sequencing, and gene panel sequencing cohorts—of average log-ratio (tumor normalized to normal) differences between adrenal vs thoracic cases divided by SD (z score). A positive z score (red) implies that the relative copy number is higher in adrenal vs thoracic cases and a negative z score (blue) implies the opposite. The inner dashed line illustrates the z score corresponding to a nominal P value cut point of .05, and the outer dotted line illustrates the z score corresponding to a multiple test-adjusted false discovery rate (FDR) cut point of 0.05. The 1-Mb bin containing MYCN is labeled, because it is the only focal copy number alteration to reach statistical significance. B) Meta-analysis by chromosome arm. “Avg Adrenal” and “Avg Thoracic” denote a weighted average copy number log-ratio for adrenal and thoracic cases, respectively. More positive/red values reflect regions of greater copy number gain and more negative/blue values reflect regions of greater copy number loss. From the difference of these values (Avg Difference), a z score and two-tailed P value were computed by inverse-variance meta-analysis. The FDR was controlled by the Benjamini-Hochberg method. Results with multiple test-adjusted statistical significance at FDR less than 0.05 are bolded.
Techniques Used: Microarray, Sequencing, Labeling, Two Tailed Test
Figure Legend Snippet: Unbiased clustering analysis of functional genomic and DNA methylation data in the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) cohort. Heatmaps and hierarchical clustering for all adrenal and thoracic (A) HuEx RNA microarray samples and (B) DNA methylation microarray samples. Rows reflect independent patient profiles and columns reflect the 200 probesets with the highest variance after (A) log2 transformation of RNA probe intensity and (B) logit transformation of methylation beta values. Columns are mean-centered and normalized by SD (z score transformation) and illustrated on a blue-yellow scale. Additional colored boxes illustrate clinical annotations for each patient according to the legend (white = missing annotation).
Techniques Used: Functional Assay, DNA Methylation Assay, Microarray, Transformation Assay, Methylation
