microarray data (INFINIUM Inc)
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INFINIUM Inc
microarray data
Microarray Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+expression+and+methylation+probe/microarray/pmc11873019-136-23-2
Average 90 stars, based on 1 article reviews
Microarray Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+expression+and+methylation+probe/microarray/pmc11873019-136-23-2
Average 90 stars, based on 1 article reviews
microarray data - by Bioz Stars,
2026-09
90/100 stars
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1) Product Images from "Comprehensive Bioinformatics Analyses and Experimental Validation of the Cell Cycle Related Protein SAPCD2 as a New Biomarker and Potential Therapeutic Target in Pancreatic Cancer"
Article Title: Comprehensive Bioinformatics Analyses and Experimental Validation of the Cell Cycle Related Protein SAPCD2 as a New Biomarker and Potential Therapeutic Target in Pancreatic Cancer
Journal: Journal of Inflammation Research
doi: 10.2147/JIR.S501850
Figure Legend Snippet: Genomic alterations, expression, and epigenetic regulation of SAPCD2 in gastrointestinal tumors. ( A ) The landscape of the copy number amplification and mutation frequency of SAPCD2 gene in various tumor types. ( B ) Potential mutations sites across the SAPCD2 protein in various cancers. Green dots, missense mutations; Black dots, truncating mutations; Brown dots, in-frame mutations. The hotspot mutation (E234K) is observed in the conserved Suppressor_APC domain. ( C ) The CNV percentage in each GI tumor. ( D ) The correlation between CNV and RNA-seq derived SAPCD2 gene expression in digestive tumors. ( E ) The differences of the patients’ survival between the CNV group and the wild type group in digestive tumors. ( F ) The diagram of the genomic structure of human SAPCD2 gene. The green box indicates the CpG island locus; the Orange boxes indicate the 6 exons’ locus; the red boxes indicate the positions of the 8 probes for evaluating the DNA methylation status; the grey arrow indicates the transcription direction of SAPCD2 gene whose cDNA is 8431 base pairs long. The width of each box indicates its relative length, and numbers within the square brackets indicates the start and end sites respectively. The 8 probes in this study are: cg15733507, cg21241219, cg21066537, cg15785720, cg03180426, cg01448891, cg14607755, cg14156314. ( G ) The summarized view of the relationship between the RNA-seq derived SAPCD2 gene expression and DNA methylation at 8 probes sites in TCGA-PAAD cohort. Each probe (Infinium Human Methylation 450 microarray data) was indicated on the left side, and the numbers on the right side indicated the correlation coefficient or P value. *p<0.05, **p<0.01, ***p<0.001. ( H ) The detailed view of the relationship between of SAPCD2 gene expression and DNA methylation at 8 probes sites in TCGA-PAAD cohort. The methylation level differed in SAPCD2 gene high and low expression group at 3 probe sites: cg21241219*, cg03180426 ***, cg14156314 ***.
Techniques Used: Expressing, Amplification, Mutagenesis, RNA Sequencing, Derivative Assay, Gene Expression, DNA Methylation Assay, Methylation, Microarray
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