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microarray datasets gse43580 and gse31210  (GraphPad Software Inc)


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    GraphPad Software Inc microarray datasets gse43580 and gse31210
    EpCAM expression is predominantly observed in epithelial cells and related tissues. A - B , RNA and protein expression levels of EpCAM, based on data from Protein Atlas ( www.proteinatlas.org ), and GTEx Portal ( https://gtexportal.org/ ) are shown, with expression ranked from high to low. C EpCAM expression is elevated in tumor tissues compared to normal tissues, as analyzed using two independent tumor-normal paired datasets: GSE18842 and HSE1007. D Analysis of EpCAM expression across different stages of NSCLC and in relation to EGFR, KRAS, and ALK oncogenic alterations. Microarray datasets GSE43580 and <t>GSE31210</t> were normalized and visualized using GraphPad. These results highlight that EpCAM expression is largely confined to normal epithelial tissues, including the gastrointestinal tract, thyroid, kidney, pancreas, breast, and lung, and is significantly upregulated in cancer tissues
    Microarray Datasets Gse43580 And Gse31210, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+dataset/pmc12211971-119-4-10?v=GraphPad+Software+Inc
    Average 90 stars, based on 1 article reviews
    microarray datasets gse43580 and gse31210 - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "Landscape of cancer associated EpCAM mutations: molecular modeling, predictive insights and impact on patient survival"

    Article Title: Landscape of cancer associated EpCAM mutations: molecular modeling, predictive insights and impact on patient survival

    Journal: BMC Cancer

    doi: 10.1186/s12885-025-14455-8

    EpCAM expression is predominantly observed in epithelial cells and related tissues. A - B , RNA and protein expression levels of EpCAM, based on data from Protein Atlas ( www.proteinatlas.org ), and GTEx Portal ( https://gtexportal.org/ ) are shown, with expression ranked from high to low. C EpCAM expression is elevated in tumor tissues compared to normal tissues, as analyzed using two independent tumor-normal paired datasets: GSE18842 and HSE1007. D Analysis of EpCAM expression across different stages of NSCLC and in relation to EGFR, KRAS, and ALK oncogenic alterations. Microarray datasets GSE43580 and GSE31210 were normalized and visualized using GraphPad. These results highlight that EpCAM expression is largely confined to normal epithelial tissues, including the gastrointestinal tract, thyroid, kidney, pancreas, breast, and lung, and is significantly upregulated in cancer tissues
    Figure Legend Snippet: EpCAM expression is predominantly observed in epithelial cells and related tissues. A - B , RNA and protein expression levels of EpCAM, based on data from Protein Atlas ( www.proteinatlas.org ), and GTEx Portal ( https://gtexportal.org/ ) are shown, with expression ranked from high to low. C EpCAM expression is elevated in tumor tissues compared to normal tissues, as analyzed using two independent tumor-normal paired datasets: GSE18842 and HSE1007. D Analysis of EpCAM expression across different stages of NSCLC and in relation to EGFR, KRAS, and ALK oncogenic alterations. Microarray datasets GSE43580 and GSE31210 were normalized and visualized using GraphPad. These results highlight that EpCAM expression is largely confined to normal epithelial tissues, including the gastrointestinal tract, thyroid, kidney, pancreas, breast, and lung, and is significantly upregulated in cancer tissues

    Techniques Used: Expressing, Microarray



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    TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Journal: Journal of Neuroinflammation

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination

    doi: 10.1186/s12974-026-03769-4

    Figure Lengend Snippet: TRIM21 is elevated in astrocytes across MS. A Analysis of TRIM21 mRNA expression in the control and white matter lesion tissues of MS patients based on gene expression profiling microarray data ( GSE138614 ). B TRIM21 mRNA levels in PBMC samples of healthy controls (n = 12) and MS patients (n = 20) were quantified by RT-qPCR. C Representative immunoblots and corresponding quantification of TRIM21 protein levels in brain tissues from EAE mice at 28 dpi (n = 5). D Representative immunoblot images and the corresponding quantitative analysis of TRIM21 protein expression in spinal cord tissues from EAE mice at 28 dpi (n = 5). E Immunofluorescence co-localization analysis of TRIM21 (red) and the astrocyte marker GFAP (green) in brain and spinal cord sections from control and EAE mice at 28 dpi (n = 5). Scale bar, 50 µm

    Article Snippet: The microarray dataset GSE138614 was retrieved from the Gene Expression Omnibus (GEO) repository of the National Center for Biotechnology Information ( https://www.ncbi.nlm.nih.gov/geo/ ).

    Techniques: Expressing, Control, Gene Expression, Microarray, Quantitative RT-PCR, Western Blot, Immunofluorescence, Marker

    SIRT3 is downregulated in RCC. ( A ) Based on the GEO GSE53757 dataset, SIRT3 mRNA levels in RCC tissues were compared with those in normal tissues. ( B ) SIRT3 protein levels in RCC tissues were analyzed in comparison to adjacent normal tissues using CPTAC data. ( C ) SIRT3 protein levels in RCC tissues and normal tissues were detected using immunohistochemistry (IHC). A scatter plot was generated to display the expression of SIRT3 in adjacent normal tissues versus RCC tissues. ( D, E ) Enrichment plots were produced to illustrate the gene expression signatures for proliferation (CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN) and migration (GOBP_ENDOTHELIAL_CELL_MIGRATION). *** P < 0.001.

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    Article Title: SIRT3 suppresses renal cancer progression by regulating IDH2 acetylation

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    Figure Lengend Snippet: SIRT3 is downregulated in RCC. ( A ) Based on the GEO GSE53757 dataset, SIRT3 mRNA levels in RCC tissues were compared with those in normal tissues. ( B ) SIRT3 protein levels in RCC tissues were analyzed in comparison to adjacent normal tissues using CPTAC data. ( C ) SIRT3 protein levels in RCC tissues and normal tissues were detected using immunohistochemistry (IHC). A scatter plot was generated to display the expression of SIRT3 in adjacent normal tissues versus RCC tissues. ( D, E ) Enrichment plots were produced to illustrate the gene expression signatures for proliferation (CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN) and migration (GOBP_ENDOTHELIAL_CELL_MIGRATION). *** P < 0.001.

    Article Snippet: The GSE53757 microarray dataset was obtained through the National Center for Biotechnology Information Gene Expression Omnibus database (NCBI GEO, https://www.ncbi.nlm.nih.gov/gds/?term=GSE53757 ).

    Techniques: Comparison, Immunohistochemistry, Generated, Expressing, Produced, Gene Expression, Migration