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high resolution micro ct system  (Bruker Corporation)


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    Structured Review

    Bruker Corporation high resolution micro ct system
    EMO improves joint histopathological changes and structural damage in CIA mice. (A) EMO's chemical structure. (B) Schematic of the animal experiment. (C) Representative photographs of the hind paws of mice in each group. (D) Representative H&E staining images of ankle joints in each group (200×); red arrow: indicates inflammatory cell infiltration. (E) Representative Safranin O–Fast Green staining images of ankle joints in each group (100×, 200×); blue arrow: indicates cartilage erosion or bone destruction. (F) <t>Representative</t> <t>Micro-CT</t> images of the hind paws of mice in each group; yellow arrows: indicates cartilage erosion or bone destruction. (G–I) Quantitative analyses of Tb.Th, BV/TV and BMD in the hind paw bones of mice (n = 6); data are presented as mean ± standard deviation (SD). ### p < 0.001 vs control group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs the model group. Control group: normal mouse group; Model group: CIA mouse group; EMO-L group: low-dose EMO group, 25 mg/kg; EMO-M group: medium-dose EMO group, 50 mg/kg; EMO-H group: high-dose EMO group, 100 mg/kg; MTX group: methotrexate group, 10 mg/kg; H&E: hematoxylin and eosin staining; TEM: transmission electron microscopy; Tb.Th: trabecular thickness; BV/TV: bone volume/total volume; BMD: bone mineral density.
    High Resolution Micro Ct System, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/micro+manager+open+source+microscope+controller+software/Micro-CT/pmc13007403-65-20-24
    Average 99 stars, based on 1 article reviews
    high resolution micro ct system - by Bioz Stars, 2026-10
    99/100 stars

    Images

    1) Product Images from "Ferroptosis inhibition and mitochondrial rescue: a novel mechanism of emodin in rheumatoid arthritis"

    Article Title: Ferroptosis inhibition and mitochondrial rescue: a novel mechanism of emodin in rheumatoid arthritis

    Journal: Redox Report : Communications in Free Radical Research

    doi: 10.1080/13510002.2026.2646383

    EMO improves joint histopathological changes and structural damage in CIA mice. (A) EMO's chemical structure. (B) Schematic of the animal experiment. (C) Representative photographs of the hind paws of mice in each group. (D) Representative H&E staining images of ankle joints in each group (200×); red arrow: indicates inflammatory cell infiltration. (E) Representative Safranin O–Fast Green staining images of ankle joints in each group (100×, 200×); blue arrow: indicates cartilage erosion or bone destruction. (F) Representative Micro-CT images of the hind paws of mice in each group; yellow arrows: indicates cartilage erosion or bone destruction. (G–I) Quantitative analyses of Tb.Th, BV/TV and BMD in the hind paw bones of mice (n = 6); data are presented as mean ± standard deviation (SD). ### p < 0.001 vs control group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs the model group. Control group: normal mouse group; Model group: CIA mouse group; EMO-L group: low-dose EMO group, 25 mg/kg; EMO-M group: medium-dose EMO group, 50 mg/kg; EMO-H group: high-dose EMO group, 100 mg/kg; MTX group: methotrexate group, 10 mg/kg; H&E: hematoxylin and eosin staining; TEM: transmission electron microscopy; Tb.Th: trabecular thickness; BV/TV: bone volume/total volume; BMD: bone mineral density.
    Figure Legend Snippet: EMO improves joint histopathological changes and structural damage in CIA mice. (A) EMO's chemical structure. (B) Schematic of the animal experiment. (C) Representative photographs of the hind paws of mice in each group. (D) Representative H&E staining images of ankle joints in each group (200×); red arrow: indicates inflammatory cell infiltration. (E) Representative Safranin O–Fast Green staining images of ankle joints in each group (100×, 200×); blue arrow: indicates cartilage erosion or bone destruction. (F) Representative Micro-CT images of the hind paws of mice in each group; yellow arrows: indicates cartilage erosion or bone destruction. (G–I) Quantitative analyses of Tb.Th, BV/TV and BMD in the hind paw bones of mice (n = 6); data are presented as mean ± standard deviation (SD). ### p < 0.001 vs control group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs the model group. Control group: normal mouse group; Model group: CIA mouse group; EMO-L group: low-dose EMO group, 25 mg/kg; EMO-M group: medium-dose EMO group, 50 mg/kg; EMO-H group: high-dose EMO group, 100 mg/kg; MTX group: methotrexate group, 10 mg/kg; H&E: hematoxylin and eosin staining; TEM: transmission electron microscopy; Tb.Th: trabecular thickness; BV/TV: bone volume/total volume; BMD: bone mineral density.

    Techniques Used: Staining, Micro-CT, Standard Deviation, Control, H&E Stain, Transmission Assay, Electron Microscopy, Molecular Weight

    Related Articles

    Control:

    Article Title: Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage
    Article Snippet: .. The knee joint specimens from both the LAC‐treated and control groups were securely mounted in ex vivo micro‐CT (IVIS, Spectrum, Bruker, Germany) to ensure proper positioning for imaging. ..

    Ex Vivo:

    Article Title: Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage
    Article Snippet: .. The knee joint specimens from both the LAC‐treated and control groups were securely mounted in ex vivo micro‐CT (IVIS, Spectrum, Bruker, Germany) to ensure proper positioning for imaging. ..

    Micro-CT:

    Article Title: Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage
    Article Snippet: .. The knee joint specimens from both the LAC‐treated and control groups were securely mounted in ex vivo micro‐CT (IVIS, Spectrum, Bruker, Germany) to ensure proper positioning for imaging. ..

    Article Title: Moxibustion Regulates the Imbalance of Cartilage Degradation and Repair in Knee Osteoarthritis Rabbits via the SDF-1/CXCR4 Axis: Is Stimulating Heat-Sensitized Acupoints More Efficacious?
    Article Snippet: Band intensity was analyzed using ImageJ software, with GAPDH serving as the internal reference protein. .. The right knee joints of the New Zealand rabbits were fixed in 4% paraformaldehyde (Servicebio, Guangzhou, China) for 24 hours and subsequently scanned using a Micro-CT system (Bruker, Germany). ..

    Article Title: Anti-migratory chitosan/BaSO4 markers with hydration in situ for long-term multimodal breast tissue imaging
    Article Snippet: Finally, compression tests (crosshead speed 1 mm/min) were conducted on the hydrated samples using a universal testing machine (Instron 34SC-1, USA) to assess their compressive strength and toughness under simulated physiological conditions (PBS, pH 7.4, 37 ◦C). .. The xerogel samples, both in their initial dry state (5 mm in length and 1.5 mm in diameter) and corresponding hydrated state, were imaged via a high-resolution micro-CT scanner (Bruker SkyScan 1272, USA). ..

    Article Title: Divergent pathways of straw versus biochar integration with manure to enhance SOC sequestration in coastal saline soils
    Article Snippet: .. Three representative large macroaggregates from each sample were scanned using a micro-CT scanner (Bruker Skyscan 1272, Germany) at 100 keV and 100 μA. ..

    Article Title: Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model
    Article Snippet: .. After scanning, the micro-CT images of the spinal specimens were imported into the NRecon reconstruction software (version 1.7; Bruker Corporation) to obtain cross-sectional images of the L1-L6 vertebrae of the rat spinal specimens. ..

    Imaging:

    Article Title: Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage
    Article Snippet: .. The knee joint specimens from both the LAC‐treated and control groups were securely mounted in ex vivo micro‐CT (IVIS, Spectrum, Bruker, Germany) to ensure proper positioning for imaging. ..

    Software:

    Article Title: OXR1 is a dual redox-mitochondrial checkpoint governing osteoclast differentiation and bone loss in an osteoporosis mouse model.
    Article Snippet: .. Reconstruction of the acquired images was performed with CTvox software (Bruker microCT, Kontich, Belgium), utilizing a ring artifact correction of 7, a smoothing factor of 2, and a beam hardening correction of 40%. ..

    Article Title: Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model
    Article Snippet: .. After scanning, the micro-CT images of the spinal specimens were imported into the NRecon reconstruction software (version 1.7; Bruker Corporation) to obtain cross-sectional images of the L1-L6 vertebrae of the rat spinal specimens. ..

    other:

    Article Title: IL-4 and arginine synergy accelerates early bone regeneration via enhanced efferocytosis and ameliorated microenvironment
    Article Snippet: The fixed femoral specimens were examined and imaged using Micro-CT (Skyscan 1276, Bruker, Kontich, Belgium) to evaluate the newly formed bone within the defect area.



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