methylation array data (INFINIUM Inc)
90
Structured Review
INFINIUM Inc
methylation array data
Methylation Array Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/methylation+array+data/methylation+array+data/pmc11229754-35-12-12
Average 90 stars, based on 1 article reviews
Methylation Array Data, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/methylation+array+data/methylation+array+data/pmc11229754-35-12-12
Average 90 stars, based on 1 article reviews
methylation array data - by Bioz Stars,
2026-09
90/100 stars
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1) Product Images from "Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data"
Article Title: Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data
Journal: Epigenetics
doi: 10.1080/15592294.2024.2375022
Figure Legend Snippet: Integration of gene expression data with methylation pathways. (a,b) Euler diagrams showing the overlap in statistically significant pathways (FDR <0.05) from gene expression and GSA results (a) and LAM (b) results. (c) Multi-dimensional enrichment analysis of promoter and gene body methylation with gene expression using mitch. Top 20 gene sets shown with the largest absolute enrichment scores after FDR filtering at 0.05.
Techniques Used: Gene Expression, Methylation
Figure Legend Snippet: Pathway-level DNA methylation alterations with chronological age. (a) Contour heatmap showing the similarity in gene methylation score ranks in the discovery and replication studies. (b) Mitch pathway enrichment scores in discovery and replication studies. Pathways with MANOVA FDR < 0.05 are shown in red while others are shaded grey. (c) Heatmap of 30 pathways with largest absolute enrichment scores after FDR filtering at 0.05. Red indicates increasing methylation and blue shows lower methylation. (d) An example of a pathway identified with this method, ‘creation of C4 and C2 activators’ shows lower methylation of member genes in both discovery and replication studies.
Techniques Used: DNA Methylation Assay, Methylation
Figure Legend Snippet: Pathway-level DNA methylation differences in natural and IVF conceived infants. (a) Contour heatmap showing the similarity in gene methylation score ranks in the Estill (HM450K) and Novakovic (EPIC) studies. (b) Mitch pathway enrichment scores in Estil and Novakovic studies. Pathways with MANOVA FDR < 0.05 are shown in red while others are shaded grey. (c) Heatmap of 30 pathways with largest absolute enrichment score after FDR filtering at 0.05. Red indicates higher methylation and blue shows lower methylation. (d) An example of a pathway identified with this joint enrichment analysis method, ‘Adrenoreceptors’ shows lower methylation of member genes in both Estill and Novakovic studies.
Techniques Used: DNA Methylation Assay, Methylation
Figure Legend Snippet: Differential pathway methylation associated with prevalence of 14 common disease states. (a) A bar plot showing the number of statistically significant pathways with higher and lower methylation identified in each prevalent condition (FDR <0.05). (b) A heatmap of enrichment scores for selected pathways across 14 common prevalent disease states. Stars indicate that the pathway was identified as being among the top five differentially methylated pathways in each direction for each condition.
Techniques Used: Methylation
Figure Legend Snippet: Differential pathway methylation associated with incidence of 19 common disease states. (a) A bar plot showing the number of statistically significant pathways with higher and lower methylation identified in each incident condition (FDR <0.05). (b) A heatmap of enrichment scores for selected pathways across 19 common incident disease states. Stars indicate that the pathway was identified as being among the top three differentially methylated pathways in each direction for each condition.
Techniques Used: Methylation
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