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CapitalBio Corporation massarray platform
Massarray Platform, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/massarray+methylation+detection/massarray+platform/pmc04658935-71-1-3
Average 90 stars, based on 1 article reviews
massarray platform - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Mass Spectrometry:

Article Title: CpG methylation of the GPX3 promoter in patients with Kashin-Beck Disease potentially promotes chondrocyte apoptosis.
Article Snippet: EZ-96 DNA methylation kit (Zymo Research, California, USA) was used to treat the genomic DNA (200 ng) of each participant with bisulfite according to the manufacturer’s instructions. .. The Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) containing a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer and RNA base-specific cleavage (Mass CLEAVE), were both employed to quantify the methylation of GPX3 CpGs. .. Quantitative methylation data was obtained via a Spectro CHIP (Agena Bioscience, California, USA) and a Mass ARRAY Compact System (Agena Bioscience, California, USA).

Methylation:

Article Title: CpG methylation of the GPX3 promoter in patients with Kashin-Beck Disease potentially promotes chondrocyte apoptosis.
Article Snippet: EZ-96 DNA methylation kit (Zymo Research, California, USA) was used to treat the genomic DNA (200 ng) of each participant with bisulfite according to the manufacturer’s instructions. .. The Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) containing a matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer and RNA base-specific cleavage (Mass CLEAVE), were both employed to quantify the methylation of GPX3 CpGs. .. Quantitative methylation data was obtained via a Spectro CHIP (Agena Bioscience, California, USA) and a Mass ARRAY Compact System (Agena Bioscience, California, USA).

Article Title: Multigenerational genetic effects of paternal cadmium exposure on ovarian granulosa cell apoptosis.
Article Snippet: To explore whether paternal cadmium (Cd) exposure causes ovarian granulosa cell (GC) apoptosis in offspring and the multigenerational genetic effects.. From postnatal day 28 (PND28) until adulthood (PND56), SPF male Sprague–Dawley (SD) rats were gavaged daily with varying concentrations of CdCl2. (0, 0.5, 2, and 8 mg/kg).. After treatment, the F1 generation was produced by mating with untreated female rats, and the F1 generation male rats were mated with untreated female rats to produce the F2 generation.

Article Title: Hypomethylation of the ENPP3 promoter region contributes to the occurrence and development of ovarian endometriosis via the AKT/mTOR/4EBP1 signaling pathway.
Article Snippet: With a UV spectrophotometer (NanoDrop 2000; Thermo Fisher Scientific, Wilmington, DE), the concentration and purity of DNA were evaluated by the absorbance at 260 nm and 280 nm. .. Quantitative methylation analysis of the DNA fragments of ENPP3 gene was performed by using Agena MAssARRAY platform (CapitalBio, Beijing, China). .. A total of 1 μg of genomic DNA from each sample was converted with sodium bisulfite using the EZ DNA methylation kit (Zymo Research, Orange, CA, USA) and the modified DNA was amplified by PCR.

Article Title: Prenatal cadmium exposure has inter-generational adverse effects on Sertoli cells through the follicle-stimulating hormone receptor pathway
Article Snippet: .. The Sequenom MassARRAY platform (CapitalBio, Beijing, China) was used to perform the quantitative methylation analysis. ..

Article Title: Loss of SETD2-mediated downregulation of intracellular and exosomal miRNA-10b determines MAPK pathway activation and multidrug resistance in renal cancer.
Article Snippet: Department of Urology, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, China Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Department of Endocrinology, School of Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou, China Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China

Article Title: DNA Hyper-methylation Associated With Schizophrenia May Lead to Increased Levels of Autoantibodies
Article Snippet: .. A Sequenom MassARRAY platform (CapitalBio) was used to perform the quantitative methylation analysis of candidate DMS. .. The PCR primers listed in were designed using Sequenom Epidesigner ( http://www.epidesigner.com ).

CpG Methylation Assay:

Article Title: Evaluating the link between DIO3-FA27 promoter methylation, biochemical indices, and heart failure progression.
Article Snippet: The genomic DNA was treated with bisulfite using EZ-96 DNA methylation kit (ZYMO Research, Irvine, CA) according to the manufacturer’s instructions and amplified by methylation-specific polymerase chain reaction (MSP). .. To measure the DIO3 CpG methylation, the Agena MassARRAY platform (CapitalBio Corporation, Beijing, China) was utilized. ..

other:

Article Title: CD2AP is a potential prognostic biomarker of renal clear cell carcinoma
Article Snippet: The Agena MassARRAY® platform (CapitalBio technology, Beijing) is used to detect methylation status of the promoter CpG site of CD2AP in multiple cells.



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A A negative correlation between ZNF334 <t>methylation</t> level and its mRNA expression (Pearson r = −0.53, R 2 = 0.28) B mRNA expression of ZNF334 in cancer and adjacent tissues of 213 liver cancer patients. C Western-blot diagram of ZNF334 expression in cancer and adjacent tissues of 12 liver cancer patients. D Methylation mass spectrum primers of ZNF334 promoter region and mass spectrometry detection product sequence (green indicates the EPIC chip probe cg07139762 site, which is in the ZNF334 promoter region; yellow indicates the <t>MassARRAY</t> methylation mass spectrometry detection sites, a total of 29). E Heat map of methylation level of ZNF334 promoter region in cancer and adjacent tissues of 25 patients with liver cancer. F The ratio of methylation degree of ZNF334 promoter in cancer and adjacent tissues (T/P) of 25 patients with liver cancer. G The average methylation degree of ZNF334 promoter in cancer and adjacent tissues of 25 patients with liver cancer. **** p < 0.0001.
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A A negative correlation between ZNF334 <t>methylation</t> level and its mRNA expression (Pearson r = −0.53, R 2 = 0.28) B mRNA expression of ZNF334 in cancer and adjacent tissues of 213 liver cancer patients. C Western-blot diagram of ZNF334 expression in cancer and adjacent tissues of 12 liver cancer patients. D Methylation mass spectrum primers of ZNF334 promoter region and mass spectrometry detection product sequence (green indicates the EPIC chip probe cg07139762 site, which is in the ZNF334 promoter region; yellow indicates the <t>MassARRAY</t> methylation mass spectrometry detection sites, a total of 29). E Heat map of methylation level of ZNF334 promoter region in cancer and adjacent tissues of 25 patients with liver cancer. F The ratio of methylation degree of ZNF334 promoter in cancer and adjacent tissues (T/P) of 25 patients with liver cancer. G The average methylation degree of ZNF334 promoter in cancer and adjacent tissues of 25 patients with liver cancer. **** p < 0.0001.
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A A negative correlation between ZNF334 <t>methylation</t> level and its mRNA expression (Pearson r = −0.53, R 2 = 0.28) B mRNA expression of ZNF334 in cancer and adjacent tissues of 213 liver cancer patients. C Western-blot diagram of ZNF334 expression in cancer and adjacent tissues of 12 liver cancer patients. D Methylation mass spectrum primers of ZNF334 promoter region and mass spectrometry detection product sequence (green indicates the EPIC chip probe cg07139762 site, which is in the ZNF334 promoter region; yellow indicates the <t>MassARRAY</t> methylation mass spectrometry detection sites, a total of 29). E Heat map of methylation level of ZNF334 promoter region in cancer and adjacent tissues of 25 patients with liver cancer. F The ratio of methylation degree of ZNF334 promoter in cancer and adjacent tissues (T/P) of 25 patients with liver cancer. G The average methylation degree of ZNF334 promoter in cancer and adjacent tissues of 25 patients with liver cancer. **** p < 0.0001.
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Image Search Results


A A negative correlation between ZNF334 methylation level and its mRNA expression (Pearson r = −0.53, R 2 = 0.28) B mRNA expression of ZNF334 in cancer and adjacent tissues of 213 liver cancer patients. C Western-blot diagram of ZNF334 expression in cancer and adjacent tissues of 12 liver cancer patients. D Methylation mass spectrum primers of ZNF334 promoter region and mass spectrometry detection product sequence (green indicates the EPIC chip probe cg07139762 site, which is in the ZNF334 promoter region; yellow indicates the MassARRAY methylation mass spectrometry detection sites, a total of 29). E Heat map of methylation level of ZNF334 promoter region in cancer and adjacent tissues of 25 patients with liver cancer. F The ratio of methylation degree of ZNF334 promoter in cancer and adjacent tissues (T/P) of 25 patients with liver cancer. G The average methylation degree of ZNF334 promoter in cancer and adjacent tissues of 25 patients with liver cancer. **** p < 0.0001.

Journal: Cell Death & Disease

Article Title: DNA hypermethylation modification promotes the development of hepatocellular carcinoma by depressing the tumor suppressor gene ZNF334

doi: 10.1038/s41419-022-04895-6

Figure Lengend Snippet: A A negative correlation between ZNF334 methylation level and its mRNA expression (Pearson r = −0.53, R 2 = 0.28) B mRNA expression of ZNF334 in cancer and adjacent tissues of 213 liver cancer patients. C Western-blot diagram of ZNF334 expression in cancer and adjacent tissues of 12 liver cancer patients. D Methylation mass spectrum primers of ZNF334 promoter region and mass spectrometry detection product sequence (green indicates the EPIC chip probe cg07139762 site, which is in the ZNF334 promoter region; yellow indicates the MassARRAY methylation mass spectrometry detection sites, a total of 29). E Heat map of methylation level of ZNF334 promoter region in cancer and adjacent tissues of 25 patients with liver cancer. F The ratio of methylation degree of ZNF334 promoter in cancer and adjacent tissues (T/P) of 25 patients with liver cancer. G The average methylation degree of ZNF334 promoter in cancer and adjacent tissues of 25 patients with liver cancer. **** p < 0.0001.

Article Snippet: MassARRAY methylation detection technology (Sequenom, USA) performed by CapitalBio Technology (Shanghai, China) was used to detect the methylation level of ZNF334 promoter (human) in carcinoma and paracancerous tissues of 25 HCC patients and Zfp334 promoter (mice) in treatment and control group.

Techniques: Methylation, Expressing, Western Blot, Mass Spectrometry, Sequencing