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Provencher Inc linear combination (lc) model software
Linear Combination (Lc) Model Software, supplied by Provencher Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/linear+combination+model/linear+combination++lc++model+software/pmc02836426-109-45-51
Average 90 stars, based on 1 article reviews
linear combination (lc) model software - by Bioz Stars, 2026-11
90/100 stars

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Software:

Article Title: Cerebral mapping of glutamate using chemical exchange saturation transfer imaging in a rat model of stress-induced sleep disturbance at 7.0T.
Article Snippet: Background: Glutamate chemical exchange saturation transfer (GluCEST) imaging has been widely used in brain psychiatric disorders.. Glutamate signal changes may help to evaluate the sleep-related disorders, and could be useful in diagnosis.. Purpose: To evaluate signal changes in the hippocampus and cortex of a rat model of stress-induced sleep disturbance using GluCEST.

Article Title: Correlations between changes in the hypothalamic-pituitary-adrenal axis and neurochemistry of the anterior cingulate gyrus in postpartum depression.
Article Snippet: Background: This study aimed to investigate associations between indicators of hypothalamic-pituitary-adrenal axis (HPA) functioning and metabolite levels in the anterior cingulate gyrus (ACG) of women with postpartum

Article Title: From Allostatic Load to Allostatic State—An Endogenous Sympathetic Strategy to Deal With Chronic Anxiety and Stress?
Article Snippet: .. The experimental 1 H magnetic resonance spectra were processed, and the quantitative composition of metabolites was determined with a custom program similar to the LC Model software package (Provencher, ), which assume that the spectrum of a mixture of known compounds is a linear combination of analyzed components. ..

Article Title: Metabolic abnormalities in the insula of patients with interictal migraine without aura: a prospective cross-sectional study
Article Snippet: .. The raw and unprocessed MRS data were exported and processed using the linear combination model (LCModel) software (version 6.3-1H; Provencher SW; http://s-provencher.com/lcmodel.shtml ). ..

Article Title: On the functional role of striatal and anterior cingulate GABA + in stimulus‐response binding
Article Snippet: .. The LC model software package [Provencher, 1993], which was used for quantifying the transmitter and metabolite concentrations reported in the main text, did not allow to control for the fractions of grey matter (GM) and white matter (WM) in the individual voxels. ..

other:

Article Title: Evidence of altered metabolism of cellular membranes in bipolar disorder comorbid with post-traumatic stress disorder.
Article Snippet: In proton magnetic resonance spectroscopy (1H MRS) studies, aberrant levels of choline-containing compounds that include glycerophosphocholine plus phosphocholine (GPC+PC), can signify alterations in the metabolism of cellular membrane phospholipids (MPLs) from a healthy baseline.. In a recent 1H MRS study, we reported increased GPC+PC in cortical and subcortical areas of adult patients with bipolar disorder I (BP-I).. Post-traumatic stress disorder (PTSD) can worsen the severity of BP-I, but it is unclear whether the effect of a PTSD comorbidity in BP-I is associated with altered MPL metabolism.

Article Title: Functional dynamics of hippocampal glutamate during associative learning assessed with in vivo 1 H functional magnetic resonance spectroscopy
Article Snippet: For each pair of averaged 1H MRS signal, the 1 H metabolites, glutamate, N-acetyl-aspartate (NAA), phosphocreatine plus creatine (PCr+Cr), trimethylamines [glycerophosphocholine plus phosphocholine (GPC+PC)], and myo -inositol, glutamine, taurine, N-acetyl-aspartylglutamate, alanine, aspartate, gamma-amino-butyric acid (GABA), and glucose, and the lipid and macromolecule resonances ( Seeger et al., 2003 ) were quantified using the Linear Combination (LC) Model software ( Provencher, 1993 ) with simulated basis set for the a priori knowledge reflecting the acquisition parameters.

Article Title: Elevated Choline-Containing Compound Levels in Rapid Cycling Bipolar Disorder
Article Snippet: GPC+PC levels were quantified using the Linear Combination (LC) Model software with a simulated basis set for the a priori knowledge ( Provencher, 2001 ), along with other metabolites, such as N-acetylaspartate (NAA), phosphocreatine plus creatine (PCr+Cr), glutamate (Glu), myo-inositol (myo-Ins) L-alanine, aspartate, γ -aminobutyric acid, glucose, glutathione, L-lactate, N-acetylaspartylglutamate, scyllo -inositol and taurine as well as lipid resonances and macromolecule resonances ( Seeger et al , 2003 ).

Control:

Article Title: On the functional role of striatal and anterior cingulate GABA + in stimulus‐response binding
Article Snippet: .. The LC model software package [Provencher, 1993], which was used for quantifying the transmitter and metabolite concentrations reported in the main text, did not allow to control for the fractions of grey matter (GM) and white matter (WM) in the individual voxels. ..



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