Review



human lambda elisa quantitation set  (Bethyl)


Bioz Verified Symbol Bethyl is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 96

    Structured Review

    Bethyl human lambda elisa quantitation set
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Human Lambda Elisa Quantitation Set, supplied by Bethyl, used in various techniques. Bioz Stars score: 96/100, based on 544 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/Human+Albumin+ELISA+Quantitation+Set/pmc05400723-52-0-6
    Average 96 stars, based on 544 article reviews
    human lambda elisa quantitation set - by Bioz Stars, 2026-10
    96/100 stars

    Images

    1) Product Images from "Stable and potent selenomab-drug conjugates"

    Article Title: Stable and potent selenomab-drug conjugates

    Journal: Cell chemical biology

    doi: 10.1016/j.chembiol.2017.02.012

    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human lambda light chain concentrations correlating with tumor burden were determined by ELISA at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Figure Legend Snippet: Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human lambda light chain concentrations correlating with tumor burden were determined by ELISA at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.

    Techniques Used: Injection, Enzyme-linked Immunosorbent Assay

    (A) Human breast cancer cell line KPL-4 was xenografted into the mammary fat pads of female NSG mice, grown to ~150 mm3, randomized into 5 groups comprising 6 mice each, and treated with i.v. (tail vein) injections of the indicated ADCs and controls four times every week at 5 mg/kg. Mean ± SD values are plotted. (B) Four female CD-1 mice were injected i.v. with 6 mg/kg of anti-HER2 scFv-Fc(Ser396Sec)/CN29. The plasma concentrations of total antibody and intact ADC were quantified by ELISA at the indicated time points, using HER2 ECD for capturing and either anti-His mAb (total antibody) or anti-MMAF mAb (intact ADC) for detection. Shown are mean ± SD values for each time point. See also Figure S5, Figure S6, Figure S7, and Table S6.
    Figure Legend Snippet: (A) Human breast cancer cell line KPL-4 was xenografted into the mammary fat pads of female NSG mice, grown to ~150 mm3, randomized into 5 groups comprising 6 mice each, and treated with i.v. (tail vein) injections of the indicated ADCs and controls four times every week at 5 mg/kg. Mean ± SD values are plotted. (B) Four female CD-1 mice were injected i.v. with 6 mg/kg of anti-HER2 scFv-Fc(Ser396Sec)/CN29. The plasma concentrations of total antibody and intact ADC were quantified by ELISA at the indicated time points, using HER2 ECD for capturing and either anti-His mAb (total antibody) or anti-MMAF mAb (intact ADC) for detection. Shown are mean ± SD values for each time point. See also Figure S5, Figure S6, Figure S7, and Table S6.

    Techniques Used: Injection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay

    KEY RESOURCES TABLE
    Figure Legend Snippet: KEY RESOURCES TABLE

    Techniques Used: Virus, Recombinant, Marker, Conjugation Assay, Proliferation Assay, Enzyme-linked Immunosorbent Assay, Quantitation Assay, Software

    Related Articles

    Clinical Proteomics:

    Article Title: Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis
    Article Snippet: Plasma samples collected from randomly selected rats were subjected to the Rat Cytokine Array (RayBiotech) containing antibodies to 48 cytokines according to the manufacturer’s instructions. .. Collected rat plasma was assayed using the HGF ELISA kit (R&D, MHG00), Human Albumin ELISA Quantitation Set (Bethyl Laboratories), and α-fetoprotein (AFP) ELISA kit (RayBiotech, ELH-AFP-1), according to the manufacturers’ protocols. .. Biochemical tests such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), ammonia, and total bilirubin were measured using DRI-CHEM NX500V (Fujifilm, Japan).

    Enzyme-linked Immunosorbent Assay:

    Article Title: Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis
    Article Snippet: Plasma samples collected from randomly selected rats were subjected to the Rat Cytokine Array (RayBiotech) containing antibodies to 48 cytokines according to the manufacturer’s instructions. .. Collected rat plasma was assayed using the HGF ELISA kit (R&D, MHG00), Human Albumin ELISA Quantitation Set (Bethyl Laboratories), and α-fetoprotein (AFP) ELISA kit (RayBiotech, ELH-AFP-1), according to the manufacturers’ protocols. .. Biochemical tests such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), ammonia, and total bilirubin were measured using DRI-CHEM NX500V (Fujifilm, Japan).

    Article Title: Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis.
    Article Snippet: .. The supernatants were assayed with Human Albumin ELISA Quantitation Set (Bethyl Laboratories) and QuantiChrom Urea Assay Kit (BioAssay Systems). .. Measurement of glucose production in iHLCs Glucose production in iHLCs was measured using the Glucose-Glo-Assay (Promega) according to the manufacturer’s protocol.

    Article Title: Compositions and methods for long term culture of hepatocytes
    Article Snippet: .. Unsupervised hierarchical clustering of RNA-Seq data was generated by hclust package in R. Biochemical Assays Human albumin was measured using the Human Albumin ELISA Quantitation kit (Bethyl Laboratories). .. Urea concentration was measured by the QuantiChromTM Urea Assay Kit (BioAssay Systems).

    Article Title: Methods of generating and expanding hematopoietic stem cells
    Article Snippet: .. The supernatant was assayed with a Human Albumin ELISA Quantitation Set kit (Bethyl Laboratories, E80-129) according to manufacturer's instructions. ..

    Article Title: Optimization of lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes for in vivo delivery of a CRISPR/Cas9 system targeting hepatitis B virus
    Article Snippet: .. Serum albumin was quantified using a Human Albumin (hAlb) ELISA Quantitation kit (Bethyl Laboratories) per the manufacturer’s instructions (Supplementary Table 2). ..

    Quantitation Assay:

    Article Title: Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis
    Article Snippet: Plasma samples collected from randomly selected rats were subjected to the Rat Cytokine Array (RayBiotech) containing antibodies to 48 cytokines according to the manufacturer’s instructions. .. Collected rat plasma was assayed using the HGF ELISA kit (R&D, MHG00), Human Albumin ELISA Quantitation Set (Bethyl Laboratories), and α-fetoprotein (AFP) ELISA kit (RayBiotech, ELH-AFP-1), according to the manufacturers’ protocols. .. Biochemical tests such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), ammonia, and total bilirubin were measured using DRI-CHEM NX500V (Fujifilm, Japan).

    Article Title: Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis.
    Article Snippet: .. The supernatants were assayed with Human Albumin ELISA Quantitation Set (Bethyl Laboratories) and QuantiChrom Urea Assay Kit (BioAssay Systems). .. Measurement of glucose production in iHLCs Glucose production in iHLCs was measured using the Glucose-Glo-Assay (Promega) according to the manufacturer’s protocol.

    Article Title: Compositions and methods for long term culture of hepatocytes
    Article Snippet: .. Unsupervised hierarchical clustering of RNA-Seq data was generated by hclust package in R. Biochemical Assays Human albumin was measured using the Human Albumin ELISA Quantitation kit (Bethyl Laboratories). .. Urea concentration was measured by the QuantiChromTM Urea Assay Kit (BioAssay Systems).

    Article Title: Methods of generating and expanding hematopoietic stem cells
    Article Snippet: .. The supernatant was assayed with a Human Albumin ELISA Quantitation Set kit (Bethyl Laboratories, E80-129) according to manufacturer's instructions. ..

    Article Title: Optimization of lipid nanoparticles loaded with ribonucleoprotein-oligonucleotide complexes for in vivo delivery of a CRISPR/Cas9 system targeting hepatitis B virus
    Article Snippet: .. Serum albumin was quantified using a Human Albumin (hAlb) ELISA Quantitation kit (Bethyl Laboratories) per the manufacturer’s instructions (Supplementary Table 2). ..

    other:

    Article Title: A vascularized liver microphysiological system captures key features of hepatic insulin resistance and monocyte infiltration
    Article Snippet: To assess hepatocyte spheroid function, stored cell supernatant was thawed at 4 °C and albumin secretion was assayed via ELISA (Bethyl Laboratories, E80-129) according to manufacturer instructions.

    Article Title: Concentrated Polymer Brush-Modified Magnetic Particles for a Diagnostic Immunoassay
    Article Snippet: Then, the supernatant was collected by centrifugation, where the amount of human albumin was quantified by an ELISA (E80-129, Human Albumin ELISA Quantitation Set, Bethyl Laboratories, Inc.).

    Article Title: Concentrated Polymer Brush-Modified Magnetic Particles for a Diagnostic Immunoassay.
    Article Snippet: Then, the supernatant was collected by centrifugation, where the amount of human albumin was quantified by an ELISA (E80-129, Human Albumin ELISA Quantitation Set, Bethyl Laboratories, Inc.).

    RNA sequencing:

    Article Title: Compositions and methods for long term culture of hepatocytes
    Article Snippet: .. Unsupervised hierarchical clustering of RNA-Seq data was generated by hclust package in R. Biochemical Assays Human albumin was measured using the Human Albumin ELISA Quantitation kit (Bethyl Laboratories). .. Urea concentration was measured by the QuantiChromTM Urea Assay Kit (BioAssay Systems).

    Generated:

    Article Title: Compositions and methods for long term culture of hepatocytes
    Article Snippet: .. Unsupervised hierarchical clustering of RNA-Seq data was generated by hclust package in R. Biochemical Assays Human albumin was measured using the Human Albumin ELISA Quantitation kit (Bethyl Laboratories). .. Urea concentration was measured by the QuantiChromTM Urea Assay Kit (BioAssay Systems).



    Similar Products

    90
    Agilent technologies lambda mouse 129-sv/j genomic dna library
    Lambda Mouse 129 Sv/J Genomic Dna Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pmc03990712-29-18-24
    Average 90 stars, based on 1 article reviews
    lambda mouse 129-sv/j genomic dna library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies lime phage clone obtained by screening a lambda library made from the 129 sv mouse strain
    Lime Phage Clone Obtained By Screening A Lambda Library Made From The 129 Sv Mouse Strain, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pmc07700840__molce___43___921_Supple-0-33-37
    Average 90 stars, based on 1 article reviews
    lime phage clone obtained by screening a lambda library made from the 129 sv mouse strain - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    96
    Bethyl human lambda elisa quantitation
    Human Lambda Elisa Quantitation, supplied by Bethyl, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/Human+Albumin+ELISA+Quantitation+Set/pmc05400723-650-46-51
    Average 96 stars, based on 1 article reviews
    human lambda elisa quantitation - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    96
    Bethyl human lambda elisa quantitation set
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Human Lambda Elisa Quantitation Set, supplied by Bethyl, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/Human+Albumin+ELISA+Quantitation+Set/pmc05400723-52-0-6
    Average 96 stars, based on 1 article reviews
    human lambda elisa quantitation set - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    90
    Agilent technologies lambda fixii 129/sv phage library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Lambda Fixii 129/Sv Phage Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pm25027639-41-17-20
    Average 90 stars, based on 1 article reviews
    lambda fixii 129/sv phage library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies lambda fix ii mouse 129/sv genomic library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Lambda Fix Ii Mouse 129/Sv Genomic Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pmc04156920-381-16-19
    Average 90 stars, based on 1 article reviews
    lambda fix ii mouse 129/sv genomic library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies the lambda mouse 129-sv/j genomic dna library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    The Lambda Mouse 129 Sv/J Genomic Dna Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/10__1074_slash_jbc__m115__650531-61-29-35
    Average 90 stars, based on 1 article reviews
    the lambda mouse 129-sv/j genomic dna library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies mouse 129/svevtachbr lambda genomic library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Mouse 129/Svevtachbr Lambda Genomic Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pm25131300-38-16-20
    Average 90 stars, based on 1 article reviews
    mouse 129/svevtachbr lambda genomic library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies lambda fixii mouse 129/svj genomic library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Lambda Fixii Mouse 129/Svj Genomic Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/pm20162674-71-8-14
    Average 90 stars, based on 1 article reviews
    lambda fixii mouse 129/svj genomic library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Agilent technologies lambda fix 11 129 mouse liver genomic library
    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human <t>lambda</t> light chain concentrations correlating with tumor burden were determined by <t>ELISA</t> at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.
    Lambda Fix 11 129 Mouse Liver Genomic Library, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lambda+129/us07534859-351-7-15
    Average 90 stars, based on 1 article reviews
    lambda fix 11 129 mouse liver genomic library - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    Image Search Results


    Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human lambda light chain concentrations correlating with tumor burden were determined by ELISA at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.

    Journal: Cell chemical biology

    Article Title: Stable and potent selenomab-drug conjugates

    doi: 10.1016/j.chembiol.2017.02.012

    Figure Lengend Snippet: Human multiple myeloma cell line U266-ffluc was i.v. (tail vein) injected into NSG mice. After 4 weeks, the mice were randomized into 3 groups comprising 8–9 mice each and treated with i.v. (tail vein) injections of 3 mg/kg of the ADC, the unconjugated antibody, and vehicle alone. (A) Human lambda light chain concentrations correlating with tumor burden were determined by ELISA at the indicated time points and plotted as mean ± SD values. The p value (t-test) compares the ADC group to the unconjugated antibody group. (B) Kaplan-Meier survival curve. The p value (log-rank test) compares the ADC group to the unconjugated antibody group. See also Figure S3 and Table S3.

    Article Snippet: Human Lambda ELISA Quantitation Set , Bethyl Laboratories , Cat#E80-116.

    Techniques: Injection, Enzyme-linked Immunosorbent Assay

    (A) Human breast cancer cell line KPL-4 was xenografted into the mammary fat pads of female NSG mice, grown to ~150 mm3, randomized into 5 groups comprising 6 mice each, and treated with i.v. (tail vein) injections of the indicated ADCs and controls four times every week at 5 mg/kg. Mean ± SD values are plotted. (B) Four female CD-1 mice were injected i.v. with 6 mg/kg of anti-HER2 scFv-Fc(Ser396Sec)/CN29. The plasma concentrations of total antibody and intact ADC were quantified by ELISA at the indicated time points, using HER2 ECD for capturing and either anti-His mAb (total antibody) or anti-MMAF mAb (intact ADC) for detection. Shown are mean ± SD values for each time point. See also Figure S5, Figure S6, Figure S7, and Table S6.

    Journal: Cell chemical biology

    Article Title: Stable and potent selenomab-drug conjugates

    doi: 10.1016/j.chembiol.2017.02.012

    Figure Lengend Snippet: (A) Human breast cancer cell line KPL-4 was xenografted into the mammary fat pads of female NSG mice, grown to ~150 mm3, randomized into 5 groups comprising 6 mice each, and treated with i.v. (tail vein) injections of the indicated ADCs and controls four times every week at 5 mg/kg. Mean ± SD values are plotted. (B) Four female CD-1 mice were injected i.v. with 6 mg/kg of anti-HER2 scFv-Fc(Ser396Sec)/CN29. The plasma concentrations of total antibody and intact ADC were quantified by ELISA at the indicated time points, using HER2 ECD for capturing and either anti-His mAb (total antibody) or anti-MMAF mAb (intact ADC) for detection. Shown are mean ± SD values for each time point. See also Figure S5, Figure S6, Figure S7, and Table S6.

    Article Snippet: Human Lambda ELISA Quantitation Set , Bethyl Laboratories , Cat#E80-116.

    Techniques: Injection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay

    KEY RESOURCES TABLE

    Journal: Cell chemical biology

    Article Title: Stable and potent selenomab-drug conjugates

    doi: 10.1016/j.chembiol.2017.02.012

    Figure Lengend Snippet: KEY RESOURCES TABLE

    Article Snippet: Human Lambda ELISA Quantitation Set , Bethyl Laboratories , Cat#E80-116.

    Techniques: Virus, Recombinant, Marker, Conjugation Assay, Proliferation Assay, Enzyme-linked Immunosorbent Assay, Quantitation Assay, Software