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illumina iscan microarray scanner  (Illumina Inc)


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    Structured Review

    Illumina Inc illumina iscan microarray scanner
    Pedigree and genetic analysis for family 1. (A) Genetic pedigree of family 1; black circle II.1 indicates the affected child (P1). (B) SeqPilot ® CNV analysis: reduced copy number for the RUNX1 exons for the index patient (green columns) compared to the patients analyzed in the same enrichment (blue), indicating a heterozygous RUNX1 -gene deletion. (C) Chromosomal <t>microarray</t> analysis: 1.56 Mb deletion (21q22.11q22.12 shown as a red bar) including RUNX1 .
    Illumina Iscan Microarray Scanner, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 97/100, based on 1731 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/iscan+microarray+scanner/iScan+System/pmc12739554-93-8-8
    Average 97 stars, based on 1731 article reviews
    illumina iscan microarray scanner - by Bioz Stars, 2026-11
    97/100 stars

    Images

    1) Product Images from "RUNX1-FPDMM in families with mild thrombocytopenia and platelet function anomalies: a case series"

    Article Title: RUNX1-FPDMM in families with mild thrombocytopenia and platelet function anomalies: a case series

    Journal: Frontiers in Medicine

    doi: 10.3389/fmed.2025.1657054

    Pedigree and genetic analysis for family 1. (A) Genetic pedigree of family 1; black circle II.1 indicates the affected child (P1). (B) SeqPilot ® CNV analysis: reduced copy number for the RUNX1 exons for the index patient (green columns) compared to the patients analyzed in the same enrichment (blue), indicating a heterozygous RUNX1 -gene deletion. (C) Chromosomal microarray analysis: 1.56 Mb deletion (21q22.11q22.12 shown as a red bar) including RUNX1 .
    Figure Legend Snippet: Pedigree and genetic analysis for family 1. (A) Genetic pedigree of family 1; black circle II.1 indicates the affected child (P1). (B) SeqPilot ® CNV analysis: reduced copy number for the RUNX1 exons for the index patient (green columns) compared to the patients analyzed in the same enrichment (blue), indicating a heterozygous RUNX1 -gene deletion. (C) Chromosomal microarray analysis: 1.56 Mb deletion (21q22.11q22.12 shown as a red bar) including RUNX1 .

    Techniques Used: Microarray

    Related Articles

    Staining:

    Article Title: Epigenome-wide DNA methylation and genome-wide genotyping in participants entered on NSABP P-1 and P-2 breast cancer prevention trials
    Article Snippet: The allele-specific extension reaction, washing, and staining were carried out using a TECAN Freedom EVO 150 liquid handler (Mannedorf, Switzerland). .. The stained beadchips were vacuum dried and imaged on an Illumina iScan instrument. .. Data Processing, Normalization, and Quality Control The resultant IDAT files were then loaded into Illumina’s GenomeStudio Methylation Module and Illumina’s Bead Array Control Reporter for preliminary analysis and quality control verification.

    QC/EQA/Proficiency:

    Article Title: Integrated genome-wide DNA methylation and transcriptomic analysis prioritizes EPHA5 as a candidate non-invasive epigenetic biomarker for oral squamous cell carcinoma
    Article Snippet: Briefly, 200 ng of bisulfite-converted DNA was processed according to the manufacturer’s standard Infinium HD methylation assay protocol, including whole-genome amplification, enzymatic fragmentation, hybridization to the BeadChip, single-base extension, fluorescent staining, and scanning. .. Arrays were scanned using the Illumina iScan System and raw intensity data were extracted and subjected to quality control using Illumina GenomeStudio software. ..

    Software:

    Article Title: Integrated genome-wide DNA methylation and transcriptomic analysis prioritizes EPHA5 as a candidate non-invasive epigenetic biomarker for oral squamous cell carcinoma
    Article Snippet: Briefly, 200 ng of bisulfite-converted DNA was processed according to the manufacturer’s standard Infinium HD methylation assay protocol, including whole-genome amplification, enzymatic fragmentation, hybridization to the BeadChip, single-base extension, fluorescent staining, and scanning. .. Arrays were scanned using the Illumina iScan System and raw intensity data were extracted and subjected to quality control using Illumina GenomeStudio software. ..

    Article Title: The NeuroBioBank whole-genome catalogue of human brain donors with central nervous system disorders.
    Article Snippet: Daniel Hupalo, Jacob L. McCauley, Lissette Gomez, Anthony J. Griswold, Gabriela Hoher, Ioanna Konidari, Jose Lorenzo, Griffin S. Parker, Julianna Pascual, Amanda R. Sandford, Patrice L. Whitehead, David A. Davis, Susanna Garamszegi, S. Humayun Gultekin, Xiaoyan Sun, Regina T. Vontell, Michael Chatigny, Darren Chernicky, Myrtha M. Constant, Isabelle G. Darling, David J. Ennulat, John M. Esposito, Kiely Morris, Elisabeth S. Lawton, Neda R. Morakabati, Phyllis Oduor, Allison P. Rodgers, Lorelle A.. Sang, Kathleen M. Sullivan, Catalina J. Tabit, Tori Turpin, Aya Zeabi, Tina Zheng, Sabina Berretta, Torsten Klengel, W. Brad Ruzicka, Derek H. Oakley, Thomas Blanchard, Eric Ho, Robert Johnson, Alexandra LeFevre, Maxwell Bustamante, Vahram Haroutunian, Christine Marino, Dushyant P. Purohit, Michael Wysocki, Jill R. Glausier, David A. Lewis, Rashed M. Nagra, Camille Alba, Julianna Martin, Elizabeth Rice, John Rosenberger, Grace Smith, Gauthaman Sukumar, Miranda Tompkins, Matthew D. Wilkerson, Clifton L. Dalgard and William K. Scott

    Genotyping:

    Article Title: Polygenicity shapes distinct brain patterns and clinical profiles of bipolar disorder
    Article Snippet: .. The samples were delivered to the Infinium Chinese Genotyping Array-24 v1.0 BeadChip (CGA), facilitated by Infinium 24-sample Infinium HTS, and then scanned using the Illumina iScan system. ..

    Hemagglutination Assay:

    Article Title: Assessment of Distributive DNA Methylation Profiling for Central Nervous System Tumor Classification Between Laboratories in the United States and Brazil
    Article Snippet: .. The main differences were the DNA input amount: 500 ng at HA versus 100 to 250 ng at SJCRH, the type of Illumina instruments used for chip scanning (NextSeq 550 at HA and iScan [Illumina] at SJCRH), and the operators performing the test. ..

    Microarray:

    Article Title: Assessment of Embryonic MicroRNAs and DNA Methylation Suggests That Chemotherapy Induces Differentiation of Germ Cell-Derived Trophoblastic Tumors
    Article Snippet: Unusual trophoblastic tumors of germ cell originepithelioid trophoblastic tumor (ETT), unclassified trophoblastic tumor (UTT), cystic trophoblastic tumor (CTT), and monophasic choriocarcinoma (MChorio)-are rare and mostly encountered postchemotherapy.. Their relationship to other germ cell tumor types and gestational tumors remains uncertain.. We used microRNA‐371~373 levels and DNA methylation profiling to compare nonchoriocarcinoma germ cell-derived trophoblastic tumors to gestational trophoblastic neoplasms and postpubertal-type teratoma.



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