Review




Structured Review

Charles River Laboratories organisms
Organisms, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/image-processing+code+scanip/organisms+strains/pm36493773-272-34-37
Average 86 stars, based on 1 article reviews
organisms - by Bioz Stars, 2026-09
86/100 stars

Images

Related Articles

Recombinant:

Article Title: Protocol for a murine transient middle cerebral artery occlusion model with local intra-arterial drug delivery.
Article Snippet: .. KEY RESOURCES TABLE REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Organisms/strains Male C57BL/6 mice Charles River Laboratories Strain code: 027 Chemicals, peptides, and recombinant proteins Chlorhexidine Gluconate 4% w/v Hibiscrub N/A Isoflurane Zoetis N/A Gluture Zoetis N/A Viscotear Liquid Gel Bausch + Lomb N/A Buprevet (0.3 mg/mL) Virbac N/A Other Leica 3M Microscope Leica Microsystems N/A Polyimide catheter (ID: 172 ± 12 μm; OD: 216 ± 12 μm) Zeus PN Zeus PN: 270903 6-0 Surgical Nylon Monofilament Suture Ethicon Inc. N/A 6-0 Coated VICRYL Ethicon Inc. N/A PeriFlux System 5000 Perimed N/A TEC 3 Isoflurane Vaporiser +Mediquip LTD Model:98723N Occlusion suture Doccol 602223PK10RE TLAT-2LV Physitemp https://www.physitemp.com/animal- temperature-control_p130 PUMP 11 Elite Harvard Apparatus Item No: 70-4504 Needle 25G (0.5 3 16 mm) BD Microlance 3 N/A 3M Micropore (Tape) 3M N/A 2 STAR Protocols 7, 104618, June 19, 2026 ..

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Article Title: Distinct supraspinal neural pathways underlie licking-induced alleviation of pain sensation and aversion in male mice.
Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit Anti-Glutamate antibody Sigma-Aldrich Cat# G6642; RRID: AB_259946 Rabbit Anti-GABA antibody Sigma-Aldrich Cat# A2052; RRID: AB_477652 Rabbit Anti-TH antibody HUABIO Cat# ET1611-12; RRID: AB_3069989 Pig Anti-c-Fos antibody SYSY Cat# 226308; RRID: AB_2905595 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150077; RRID: AB_2630356 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 555) Abcam Cat# ab150078; RRID: AB_2722519 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647) Abcam Cat# ab150079; RRID: AB_2722623 Goat Anti-Guinea pig IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150185; RRID: AB_2736871 Bacterial and virus strains rAAV-Ef1α-DIO-N2cG Brain Case Cat# BC-0304 rAAV-Ef1α-DIO-mCherry-F2A-TVA Brain Case Cat# BC-0061 CVS-EnvA-ΔG-EGFP Brain Case Cat# BC-RV-CVS EnVA461 rAAV2/1-hSyn-Cre-WPRE-hGH-pA BrainVTA Cat# PT-0136 rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0795 rAAV-Ef1α-DIO-hChR2 (H134R)-mCherry-WPRE-pA BrainVTA Cat# PT-0002 rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0043 rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0987 retro-rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-hSyn-CRE-WPRE-hGH BrainVTA Cat# PT-0136 retro-rAAV-Ef1α-DIO-EGFP-WPRE-hGH BrainVTA Cat# PT-0795 retro-rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0013 rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 retro-rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 rAAV-CAG-DIO-WGA-FLP-WPRE-hGH-pA BrainVTA Cat# PT-0557 rAAV-EF1a-fDIO-mCherry-WPRE-hGH-pA BrainVTA Cat# PT-1046 rAAV-cfos-tTA-WPRE-hGH-pA BrainVTA Cat# PT-3022 rAAV-TRE-tight-EGFP-WPREs BrainVTA Cat# PT-9667 Chemicals, peptides, and recombinant proteins TTX Tauto Biotech Cat# E− 2968 4-AP MCE HY-B0604 CNQX Tocris Cat# 0190 Bicuculine Selleck Cat# S7071 Clozapine N-oxide TargetMol Cat# T4494 Experimental models: Organisms/strains Mouse: wild type C57BL/6J Charles River N/A Mouse: VgluT2-Cre Jackson Laboratory 016963 Mouse: Vgat-Cre Jackson Laboratory 028862 Software and algorithms Illustrator CS6 Adobe https://www.adobe.com/products/illustrator.html GraphPad Prism 8 GraphPad Software https://www.graphpad.com/scientific-software/ ZEN Zeiss https://www.zeiss.com/microscopy/int/products/ microscope-software/zen-lite.html (Continued on next page) 16 Cell Reports 45, 117363, May 26, 2026 ..

Microscopy:

Article Title: Protocol for a murine transient middle cerebral artery occlusion model with local intra-arterial drug delivery.
Article Snippet: .. KEY RESOURCES TABLE REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Organisms/strains Male C57BL/6 mice Charles River Laboratories Strain code: 027 Chemicals, peptides, and recombinant proteins Chlorhexidine Gluconate 4% w/v Hibiscrub N/A Isoflurane Zoetis N/A Gluture Zoetis N/A Viscotear Liquid Gel Bausch + Lomb N/A Buprevet (0.3 mg/mL) Virbac N/A Other Leica 3M Microscope Leica Microsystems N/A Polyimide catheter (ID: 172 ± 12 μm; OD: 216 ± 12 μm) Zeus PN Zeus PN: 270903 6-0 Surgical Nylon Monofilament Suture Ethicon Inc. N/A 6-0 Coated VICRYL Ethicon Inc. N/A PeriFlux System 5000 Perimed N/A TEC 3 Isoflurane Vaporiser +Mediquip LTD Model:98723N Occlusion suture Doccol 602223PK10RE TLAT-2LV Physitemp https://www.physitemp.com/animal- temperature-control_p130 PUMP 11 Elite Harvard Apparatus Item No: 70-4504 Needle 25G (0.5 3 16 mm) BD Microlance 3 N/A 3M Micropore (Tape) 3M N/A 2 STAR Protocols 7, 104618, June 19, 2026 ..

Article Title: Distinct supraspinal neural pathways underlie licking-induced alleviation of pain sensation and aversion in male mice.
Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit Anti-Glutamate antibody Sigma-Aldrich Cat# G6642; RRID: AB_259946 Rabbit Anti-GABA antibody Sigma-Aldrich Cat# A2052; RRID: AB_477652 Rabbit Anti-TH antibody HUABIO Cat# ET1611-12; RRID: AB_3069989 Pig Anti-c-Fos antibody SYSY Cat# 226308; RRID: AB_2905595 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150077; RRID: AB_2630356 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 555) Abcam Cat# ab150078; RRID: AB_2722519 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647) Abcam Cat# ab150079; RRID: AB_2722623 Goat Anti-Guinea pig IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150185; RRID: AB_2736871 Bacterial and virus strains rAAV-Ef1α-DIO-N2cG Brain Case Cat# BC-0304 rAAV-Ef1α-DIO-mCherry-F2A-TVA Brain Case Cat# BC-0061 CVS-EnvA-ΔG-EGFP Brain Case Cat# BC-RV-CVS EnVA461 rAAV2/1-hSyn-Cre-WPRE-hGH-pA BrainVTA Cat# PT-0136 rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0795 rAAV-Ef1α-DIO-hChR2 (H134R)-mCherry-WPRE-pA BrainVTA Cat# PT-0002 rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0043 rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0987 retro-rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-hSyn-CRE-WPRE-hGH BrainVTA Cat# PT-0136 retro-rAAV-Ef1α-DIO-EGFP-WPRE-hGH BrainVTA Cat# PT-0795 retro-rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0013 rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 retro-rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 rAAV-CAG-DIO-WGA-FLP-WPRE-hGH-pA BrainVTA Cat# PT-0557 rAAV-EF1a-fDIO-mCherry-WPRE-hGH-pA BrainVTA Cat# PT-1046 rAAV-cfos-tTA-WPRE-hGH-pA BrainVTA Cat# PT-3022 rAAV-TRE-tight-EGFP-WPREs BrainVTA Cat# PT-9667 Chemicals, peptides, and recombinant proteins TTX Tauto Biotech Cat# E− 2968 4-AP MCE HY-B0604 CNQX Tocris Cat# 0190 Bicuculine Selleck Cat# S7071 Clozapine N-oxide TargetMol Cat# T4494 Experimental models: Organisms/strains Mouse: wild type C57BL/6J Charles River N/A Mouse: VgluT2-Cre Jackson Laboratory 016963 Mouse: Vgat-Cre Jackson Laboratory 028862 Software and algorithms Illustrator CS6 Adobe https://www.adobe.com/products/illustrator.html GraphPad Prism 8 GraphPad Software https://www.graphpad.com/scientific-software/ ZEN Zeiss https://www.zeiss.com/microscopy/int/products/ microscope-software/zen-lite.html (Continued on next page) 16 Cell Reports 45, 117363, May 26, 2026 ..

other:

Article Title: A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity.
Article Snippet: SK-N-SHm Thirant et al.12 N/A SH-SY5Y ATCC CRL-2266; RRID: CVCL_0019 SK-N-BE(2)C ATCC CRL-2268; RRID: CVCL_0529 5Y clone MES This paper, Louis-Brennetot, Peltier et al., in preparation N/A CLB-GA Boeva et al.3 RRID:CVCL_9529 SH-EP Boeva et al.3 RRID:CVCL_0524 Experimental models: Organisms/strains 8-week-old Swiss Nude (Crl:NU(Ico)-Foxn1nu Charles River Laboratories Cat#620 Oligonucleotides siCT: UGGUUUACAUGUCGACUAA Dharmacon D-001810-01 siYAP #1: GACAUCUUCUGGUCAGAGA Dharmacon custom siYAP #3: UGAGAACAAUGACGACCAA Dharmacon J-012200-06 siYAP #4: CCACCAAGCUAGAUAAAGA Dharmacon J-012200-08 siTAZ #2: AGGUACUUCCUCAAUCACA Dharmacon custom siTAZ #3: GGACAAACACCCAUGAACA Dharmacon J-009608-06 sgRNA #1: CATCAGATCGTGCACGTCCGCGG This paper N/A sgRNA #2: CGACTCCTTCTTCAAGCCGCCGG This paper N/A YAP1_1F: AAGGGAGTTGGAGGGAAAAA This paper N/A YAP1_1R: CCACCCCAGCTAGAGTTCC This paper N/A mCherry-T2A-YAP1 F: agacacagcaccggcggcatg gacgagctgtacaagGGCTCCGGCG AGGGCAGGGGAAGTCTTCTA ACATGCGGGGACGTGGAGGA AAATCCCGGCCCAATGGATCC CGGGCAGCA This paper N/A (Continued on next page) Cell Reports 45, 117351, May 26, 2026 17

Software:

Article Title: Giredestrant immobilizes the estrogen receptor to exert potent antitumor efficacy against ER-active breast cancers.
Article Snippet: ZR-75-1 ATCC ATCC® CRL-1500TM .. Experimental models: Organisms/strains HCC1419Mouse: NOD.CB17-Prkdcscid/NCrCr Charles River Laboratories Strain code: 394 Mouse: Crl:NU(NCr)-Foxn1nu Charles River Laboratories Strain code: 088 Software and algorithms R R Core Team, 2015 https://www.r-project.org/about.html BioConductor Huber et al.62 https://www.bioconductor.org/ (Continued on next page) ll OPEN ACCESSArticle Cell Chemical Biology 33, 1–14.e1–e11, July 16, 2026 e1 .. ER-expressing breast cancer cell lines were cultured using standard aseptic tissue culture techniques at 37◦C in RPMI medium supplemented with 10% FBS, 2mM L-Glutamine (Catalog 10440, Sigma), 1× Minimum Essential Media, Non-Essential Amino Acids (MEM NEAA, Catalog No. 11140–0500, Thermo Fisher) and 1× Antibiotic-Antimycotic (Catalog No.15240–112, Thermo Fisher).

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Article Title: Distinct supraspinal neural pathways underlie licking-induced alleviation of pain sensation and aversion in male mice.
Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit Anti-Glutamate antibody Sigma-Aldrich Cat# G6642; RRID: AB_259946 Rabbit Anti-GABA antibody Sigma-Aldrich Cat# A2052; RRID: AB_477652 Rabbit Anti-TH antibody HUABIO Cat# ET1611-12; RRID: AB_3069989 Pig Anti-c-Fos antibody SYSY Cat# 226308; RRID: AB_2905595 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150077; RRID: AB_2630356 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 555) Abcam Cat# ab150078; RRID: AB_2722519 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647) Abcam Cat# ab150079; RRID: AB_2722623 Goat Anti-Guinea pig IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150185; RRID: AB_2736871 Bacterial and virus strains rAAV-Ef1α-DIO-N2cG Brain Case Cat# BC-0304 rAAV-Ef1α-DIO-mCherry-F2A-TVA Brain Case Cat# BC-0061 CVS-EnvA-ΔG-EGFP Brain Case Cat# BC-RV-CVS EnVA461 rAAV2/1-hSyn-Cre-WPRE-hGH-pA BrainVTA Cat# PT-0136 rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0795 rAAV-Ef1α-DIO-hChR2 (H134R)-mCherry-WPRE-pA BrainVTA Cat# PT-0002 rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0043 rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0987 retro-rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-hSyn-CRE-WPRE-hGH BrainVTA Cat# PT-0136 retro-rAAV-Ef1α-DIO-EGFP-WPRE-hGH BrainVTA Cat# PT-0795 retro-rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0013 rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 retro-rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 rAAV-CAG-DIO-WGA-FLP-WPRE-hGH-pA BrainVTA Cat# PT-0557 rAAV-EF1a-fDIO-mCherry-WPRE-hGH-pA BrainVTA Cat# PT-1046 rAAV-cfos-tTA-WPRE-hGH-pA BrainVTA Cat# PT-3022 rAAV-TRE-tight-EGFP-WPREs BrainVTA Cat# PT-9667 Chemicals, peptides, and recombinant proteins TTX Tauto Biotech Cat# E− 2968 4-AP MCE HY-B0604 CNQX Tocris Cat# 0190 Bicuculine Selleck Cat# S7071 Clozapine N-oxide TargetMol Cat# T4494 Experimental models: Organisms/strains Mouse: wild type C57BL/6J Charles River N/A Mouse: VgluT2-Cre Jackson Laboratory 016963 Mouse: Vgat-Cre Jackson Laboratory 028862 Software and algorithms Illustrator CS6 Adobe https://www.adobe.com/products/illustrator.html GraphPad Prism 8 GraphPad Software https://www.graphpad.com/scientific-software/ ZEN Zeiss https://www.zeiss.com/microscopy/int/products/ microscope-software/zen-lite.html (Continued on next page) 16 Cell Reports 45, 117363, May 26, 2026 ..

Article Title: Aberrant prefrontal activity and arousal level correlate with action initiation and response vigor in rats
Article Snippet: .. 530 531 Key Resources Table 532 REAGENT or RESOURCE SOURCE IDENTIFIER Deposited data Data https://etsin.fairdata.fi / https://doi.org/10.2 3729/fd-fde5397bd01f-368a-9be1a750d5f4d589 Experimental models: Organisms/strains Rat (male, Lister-hooded, out-bred) Charles River (Germany) Software and algorithms Code https://etsin.fairdata.fi / https://doi.org/10.2 3729/fd-fde5397bd01f-368a-9be1a750d5f4d589 JASP (Bayesian statistical analysis) https://jasp-stats.org/ Version 0.19 (Intel) Jo urn al P e-p roo f 12 Other Multi-electrode probes Neuronexus A2x32 or Cambridge Neurotech H9x64 533 534 Declaration of generative AI and AI-assisted technologies 535 During the preparation of this work, the authors did not use an AI tools. ..

Article Title: Perinatal infection elicits clonally restricted T follicular helper cell responses that drive antibody-mediated viral control.
Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Experimental models: Organisms/strains Mus musculus: C57BL/6J (wt) Charles River JAX: 000664 Mus musculus: T11μMT (BCRres) mice Klein et al.41 N/A Mus musculus: MHCII-/- mice Madsen et al.93 N/A Mus musculus: CD40-/- mice Kawabe et al.94 N/A Mus musculus: IL21R-/- mice Fröhlich et al.95 N/A Mus musculus: CD8-/- mice Fung-Leung et al.55,96 N/A Mus musculus: KL25HL mice (HkiL-RAG-/-) Florova et al.45 N/A Mus musculus: KL25HL mice Fallet et al.97 N/A Mus musculus: AID-/- mice Muramatsu et al.98 N/A Mus musculus: sIgM-/- mice Tsiantoulas et al.99 N/A Mus musculus: Bcl6fl/flCD4Cre mice Kaji et al.100 N/A Mus musculus: SM1 mice Oxenius et al.20 N/A Mus musculus: Rag2-/- mice Hao and Rajewsky101 N/A Mus musculus: KL25HLxMHCII-/- mice This paper N/A Mus musculus: KL25HLxCD40-/- mice This paper N/A Mus musculus: sIgM-/-AID-/- mice This paper N/A Mus musculus: SM1xRag-/- mice This paper N/A Software and algorithms Prism 10.6.0 GraphPad Software RRID: SCR_002798 FlowJo 10.5.3 Becton Dickinson & Company RRID: SCR_008520 Adobe Illustrator CC 2022 Adobe Photoshop RRID:SCR_010279 Gen5 Agilent BioTek RRID: SCR_017317 STAR 2.7.0c Dobin et al.102 N/A R 4.2.2 R Core Team https://www.R-project.org/. ..

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Immunohistochemistry:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Transcriptomics:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Control:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Knock-Out:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

shRNA:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Real-time Polymerase Chain Reaction:

Article Title: SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization.
Article Snippet: Upon arrival at the animal core facility of Southern University of Science and Technology, mice were acclimated for 1 week in a barrier facility to minimize the potential effects of .. REAGENT or RESOURCE SOURCE IDENTIFIER M&R HRP/DAB Detection IHC Kit Vazyme Cat#HC301-01; Lot#7E2762K4 Deposited data Transcriptomics: A-375 control and SEPHS2 knockout cells This paper GSE:324223 Proteomics:A-375 control and SEPHS2 knockout cells This paper PXD076137 Experimental models: Cell lines A-375 ATCC Cat#CRL-1619 HeLa ATCC Cat#CCL-2 A2058 CellCook Cat#CC1805 HEK-293FT CellCook Cat#CC4046 MCF-7 CellCook Cat#CC0302 Experimental models: Organisms/strains BALB/c nude mice Charles River Laboratories Cat401 NCG[(Prkdc)KO/KO∼(Il2rg)KO/KO] mice GemPharmatech Cat#T001475 Oligonucleotides See Table S1 for the shRNA and sgRNA for gene deficiency This paper N/A See Table S2 for the primers used for real-time qPCR This paper N/A Recombinant DNA pLKO.1-TCR Addgene Cat#10878 psPAX2 Addgene Cat#12260 pMD2.G Addgene Cat#12259 LentiCRISPR v2 Addgene Cat#52961 pCMV-HA-UB-Neo MiaoLing bio Cat#P51735 pCMV-PCK1(human)-3×Flag-Neo MiaoLing bio Cat#P49543 Software and algorithms Graphpad Prism 10 GraphPad Software https://www.graphpad.com/ FIJI (ImageJ) NIH https://imagej.net/software/fiji/ FlowJo Software 10.10 TreeStar Inc https://www.flowjo.com/ BioRender.com BioRender https://www.biorender.com/ QuantStudioTM Design & Analysis Software real-time PCR https://www.thermofisher.cn/cn/zh/home/ technical-resources/software-downloads/ quantstudio-3-5-real-time-pcr-systems.html SnapGene 4.3.6 SnapGene https://www.snapgene.com/ TBtools-II Chen et al. https://apps.microsoft.com/detail/ 9nvr9lb426p2?hl=zh-cn&gl=CN R version 4.2.2 R https://cran.r-project.org/bin/windows/base/ Wave Seahorse https://www.agilent.com.cn/zh-cn/product/cell- analysis/real-time-cell-metabolic-analysis/xfsoftware/software-download-for-seahorse-wavepro-software Cell Reports 45, 117297, May 26, 2026 17 transportation stress on experimental outcomes. ..

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Virus:

Article Title: Distinct supraspinal neural pathways underlie licking-induced alleviation of pain sensation and aversion in male mice.
Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Rabbit Anti-Glutamate antibody Sigma-Aldrich Cat# G6642; RRID: AB_259946 Rabbit Anti-GABA antibody Sigma-Aldrich Cat# A2052; RRID: AB_477652 Rabbit Anti-TH antibody HUABIO Cat# ET1611-12; RRID: AB_3069989 Pig Anti-c-Fos antibody SYSY Cat# 226308; RRID: AB_2905595 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150077; RRID: AB_2630356 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 555) Abcam Cat# ab150078; RRID: AB_2722519 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647) Abcam Cat# ab150079; RRID: AB_2722623 Goat Anti-Guinea pig IgG H&L (Alexa Fluor® 488) Abcam Cat# ab150185; RRID: AB_2736871 Bacterial and virus strains rAAV-Ef1α-DIO-N2cG Brain Case Cat# BC-0304 rAAV-Ef1α-DIO-mCherry-F2A-TVA Brain Case Cat# BC-0061 CVS-EnvA-ΔG-EGFP Brain Case Cat# BC-RV-CVS EnVA461 rAAV2/1-hSyn-Cre-WPRE-hGH-pA BrainVTA Cat# PT-0136 rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0795 rAAV-Ef1α-DIO-hChR2 (H134R)-mCherry-WPRE-pA BrainVTA Cat# PT-0002 rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0043 rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-Ef1α-DIO-hM4D(Gi)-EGFP-WPRE-pA BrainVTA Cat# PT-0987 retro-rAAV-Ef1α-DIO-hM3D(Gq)-mCherry-WPRE-pA BrainVTA Cat# PT-0042 retro-rAAV-hSyn-CRE-WPRE-hGH BrainVTA Cat# PT-0136 retro-rAAV-Ef1α-DIO-EGFP-WPRE-hGH BrainVTA Cat# PT-0795 retro-rAAV-Ef1α-DIO-mCherry-WPRE-hGH BrainVTA Cat# PT-0013 rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 retro-rAAV-Ef1α-DIO-GCaMP6s-WPRE-pA BrainVTA Cat# PT-0071 rAAV-CAG-DIO-WGA-FLP-WPRE-hGH-pA BrainVTA Cat# PT-0557 rAAV-EF1a-fDIO-mCherry-WPRE-hGH-pA BrainVTA Cat# PT-1046 rAAV-cfos-tTA-WPRE-hGH-pA BrainVTA Cat# PT-3022 rAAV-TRE-tight-EGFP-WPREs BrainVTA Cat# PT-9667 Chemicals, peptides, and recombinant proteins TTX Tauto Biotech Cat# E− 2968 4-AP MCE HY-B0604 CNQX Tocris Cat# 0190 Bicuculine Selleck Cat# S7071 Clozapine N-oxide TargetMol Cat# T4494 Experimental models: Organisms/strains Mouse: wild type C57BL/6J Charles River N/A Mouse: VgluT2-Cre Jackson Laboratory 016963 Mouse: Vgat-Cre Jackson Laboratory 028862 Software and algorithms Illustrator CS6 Adobe https://www.adobe.com/products/illustrator.html GraphPad Prism 8 GraphPad Software https://www.graphpad.com/scientific-software/ ZEN Zeiss https://www.zeiss.com/microscopy/int/products/ microscope-software/zen-lite.html (Continued on next page) 16 Cell Reports 45, 117363, May 26, 2026 ..

SYBR Green Assay:

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Multiplex Assay:

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Protease Inhibitor:

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Lysis:

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.

Bicinchoninic Acid Protein Assay:

Article Title: Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex.
Article Snippet: Article Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex Highlights • SST and PV interneurons in the PL differentially regulate methamphetamine craving • LHGABA → PLSST and AMGlu → PLPV circuits drive stagespecific craving • KCNC2 upregulation in interneurons underlies distinct neuronal excitability changes • Specific knockdown of KCNC2 reduces craving during early and prolonged withdrawal Authors Sai Shi, Yi-Wen Sun, Jin-Jun Ding, ..., Fang Liu, Ti-Fei Yuan, Min Zhao Correspondence fang.liu@camh.ca (F.L.), ytf0707@126.com (T..-F.Y.), drminzhao@smhc.org.cn (M.Z.). In brief Shi et al. reveal that two distinct interneurons in the PL control the incubation of methamphetamine craving during different withdrawal stages.. They uncover a circuit-switch principle and propose a key molecular mediator, offering phase-specific therapeutic strategies to reduce relapse.



Similar Products

90
Simpleware Ltd image-processing code scanip
Image Processing Code Scanip, supplied by Simpleware Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/image-processing+code+scanip/image+processing+package+scanip/pm38217252-200-7-10
Average 90 stars, based on 1 article reviews
image-processing code scanip - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results