Review




Structured Review

CapitalBio Corporation microarray laser scanner
Chinese health biotech firms interviewed and their product/technology portfolios a
Microarray Laser Scanner, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+microarray+laser+scanner/microarray+scanner/pmc07096943-69-52-51
Average 90 stars, based on 1 article reviews
microarray laser scanner - by Bioz Stars, 2026-09
90/100 stars

Images

1) Product Images from "Chinese health biotech and the billion-patient market"

Article Title: Chinese health biotech and the billion-patient market

Journal: Nature Biotechnology

doi: 10.1038/nbt0108-37

Chinese health biotech firms interviewed and their product/technology portfolios a
Figure Legend Snippet: Chinese health biotech firms interviewed and their product/technology portfolios a

Techniques Used: Recombinant, Produced, Expressing, Enzyme-linked Immunosorbent Assay, Diagnostic Assay, Sandwich ELISA, Marker, Incubation, Cell Culture, Microarray, Software, Immunoprecipitation, Injection, Functional Assay, Calcium Assay, Clone Assay, Hybridization, Immunohistochemistry, Transgenic Assay, Knock-Out, Sequencing, Real-time Polymerase Chain Reaction, Genetically Modified, Histone Deacetylase Assay, In Vivo, Modification, Plasmid Preparation, Isolation, Mutagenesis, In Situ Hybridization, DNA Sequencing, Animal Model

Collaborations/partnerships between companies interviewed and foreign entities
Figure Legend Snippet: Collaborations/partnerships between companies interviewed and foreign entities

Techniques Used: Expressing, Synthesized, Microarray, Functional Assay, Western Blot, Luminex, Histone Deacetylase Assay, Software

Related Articles

Microarray:

Article Title: Identification EXOSC4 as a novel autoantigen of interstitial lung disease in rheumatoid arthritis.
Article Snippet: The protein chips were then incubated with 1:400 dilution of Cy3-coupled goat anti-human IgG antibody(Bioss, Beijing, China)and washed three times with PBST. .. The microarrays were scanned using a microarray scanner (CapitalBio, Beijing, China). .. The 96-well plates were coated with 0.1 μg/mL of recombinant EXOSC4 proteins (Proteintech, Wuhan, China), overnight at 4°C, followed by 1 h block with 5% BSA at 37°C.

Article Title: Chinese health biotech and the billion-patient market
Article Snippet: Bio-Bridge Science , Exclusive out-license of papillomavirus pseudovirus technology to Loyola University (Chicago).. .. CapitalBio , Joint R&D and commercialization programs in China with Affymetrix (Santa Clara, CA, USA) for gene expression profiling and genotyping services (including the development of an advanced GeneChip-compatible point-of-care system) using Affymetrix's photolithographically synthesized oligonucleotide chip technology. Provided non-exclusive rights to Alpha Innotech (San Leandro, CA, USA) for marketing of CapitalBio's microarray laser scanner. Deal to undertake joint product development, manufacturing in China, technology transfer, services and products mutual representation with BioTools (Madrid). Deal to distribute Becton Dickinson (Franklin Lakes, NJ, USA) products in China. Exclusive rights to distribute certain products from Enzo Biochem (New York), BioMachines (Research Triangle Park, NC, USA), Aviva Systems Biology (San Diego), Macherey-Nagel (Düren, Germany), Advalytix (Brunnthal, Germany) in China. Exclusive rights to MediBic (Tokyo) to market CapitalBio's pharmacogenomic services in Japan. Exclusive rights to distribute certain CapitalBio products given to Greenmate Biotech (Seoul, Korea) in Korea, FK Biotec (Port Alegre, Brazil) in Brazil and VitroLab (Istanbul, Turkey) in Turkey. Nonexclusive distribution rights to certain CapitalBio products provided to TechnoConcept (New Delhi, India) and Viswagen Biotech (Kerala, India) in India and Australian Biosearch (Karrinyup, Australia) in Australia.. .. HD Biosciences , Codevelopment of functional assays for several identified GPCRs and ion channels with Organon. Under a nondisclosure agreement, undertaking assay development and hit-to-lead solution for GPCR and kinase targets with two major Western pharmaceutical companies. Cooperation agreement to develop GPCR screening models with Novasite Pharmaceuticals (San Diego)..

Article Title: WDR73 Depletion Destabilizes PIP4K2C Activity and Impairs Focal Adhesion Formation in Galloway–Mowat Syndrome
Article Snippet: .. Finally, the microarray was scanned using a microarray scanner (CapitalBio, Beijing, China). ..

Article Title: Microarray Expression Profiling and Raman Spectroscopy Reveal Anti-Fatty Liver Action of Berberine in a Diet-Induced Larval Zebrafish Model
Article Snippet: The Agilent zebrafish (V3) gene expression microarray 4×44K (Design ID 026437) was used for microarray analysis. .. The process of microarray scanning was carried out by CapitalBio Corporation (Beijing, China) as previously described ( ). ..

Article Title: Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Article Snippet: .. Finally, the samples were scanned by a microarray scanner (532 nm) (CapitalBio, Beijing, China). ..

Article Title: One-step time-resolved cascade logic gate microfluidic chip for home testing of SARS-CoV-2 and flu B.
Article Snippet: Home testing technology strategy is critical for early screening of disease.. However, current home testing technologies often require complex processes, which limits their application.. In this study, a time-resolved cascade logic gate microfluidic chip (TCLMC) was revealed to enable capillary force-based one-step operation without manual intervention or professional equipment.

Gene Expression:

Article Title: Chinese health biotech and the billion-patient market
Article Snippet: Bio-Bridge Science , Exclusive out-license of papillomavirus pseudovirus technology to Loyola University (Chicago).. .. CapitalBio , Joint R&D and commercialization programs in China with Affymetrix (Santa Clara, CA, USA) for gene expression profiling and genotyping services (including the development of an advanced GeneChip-compatible point-of-care system) using Affymetrix's photolithographically synthesized oligonucleotide chip technology. Provided non-exclusive rights to Alpha Innotech (San Leandro, CA, USA) for marketing of CapitalBio's microarray laser scanner. Deal to undertake joint product development, manufacturing in China, technology transfer, services and products mutual representation with BioTools (Madrid). Deal to distribute Becton Dickinson (Franklin Lakes, NJ, USA) products in China. Exclusive rights to distribute certain products from Enzo Biochem (New York), BioMachines (Research Triangle Park, NC, USA), Aviva Systems Biology (San Diego), Macherey-Nagel (Düren, Germany), Advalytix (Brunnthal, Germany) in China. Exclusive rights to MediBic (Tokyo) to market CapitalBio's pharmacogenomic services in Japan. Exclusive rights to distribute certain CapitalBio products given to Greenmate Biotech (Seoul, Korea) in Korea, FK Biotec (Port Alegre, Brazil) in Brazil and VitroLab (Istanbul, Turkey) in Turkey. Nonexclusive distribution rights to certain CapitalBio products provided to TechnoConcept (New Delhi, India) and Viswagen Biotech (Kerala, India) in India and Australian Biosearch (Karrinyup, Australia) in Australia.. .. HD Biosciences , Codevelopment of functional assays for several identified GPCRs and ion channels with Organon. Under a nondisclosure agreement, undertaking assay development and hit-to-lead solution for GPCR and kinase targets with two major Western pharmaceutical companies. Cooperation agreement to develop GPCR screening models with Novasite Pharmaceuticals (San Diego)..

Synthesized:

Article Title: Chinese health biotech and the billion-patient market
Article Snippet: Bio-Bridge Science , Exclusive out-license of papillomavirus pseudovirus technology to Loyola University (Chicago).. .. CapitalBio , Joint R&D and commercialization programs in China with Affymetrix (Santa Clara, CA, USA) for gene expression profiling and genotyping services (including the development of an advanced GeneChip-compatible point-of-care system) using Affymetrix's photolithographically synthesized oligonucleotide chip technology. Provided non-exclusive rights to Alpha Innotech (San Leandro, CA, USA) for marketing of CapitalBio's microarray laser scanner. Deal to undertake joint product development, manufacturing in China, technology transfer, services and products mutual representation with BioTools (Madrid). Deal to distribute Becton Dickinson (Franklin Lakes, NJ, USA) products in China. Exclusive rights to distribute certain products from Enzo Biochem (New York), BioMachines (Research Triangle Park, NC, USA), Aviva Systems Biology (San Diego), Macherey-Nagel (Düren, Germany), Advalytix (Brunnthal, Germany) in China. Exclusive rights to MediBic (Tokyo) to market CapitalBio's pharmacogenomic services in Japan. Exclusive rights to distribute certain CapitalBio products given to Greenmate Biotech (Seoul, Korea) in Korea, FK Biotec (Port Alegre, Brazil) in Brazil and VitroLab (Istanbul, Turkey) in Turkey. Nonexclusive distribution rights to certain CapitalBio products provided to TechnoConcept (New Delhi, India) and Viswagen Biotech (Kerala, India) in India and Australian Biosearch (Karrinyup, Australia) in Australia.. .. HD Biosciences , Codevelopment of functional assays for several identified GPCRs and ion channels with Organon. Under a nondisclosure agreement, undertaking assay development and hit-to-lead solution for GPCR and kinase targets with two major Western pharmaceutical companies. Cooperation agreement to develop GPCR screening models with Novasite Pharmaceuticals (San Diego)..

Fluorescence:

Article Title: One-step time-resolved cascade logic gate microfluidic chip for home testing of SARS-CoV-2 and flu B.
Article Snippet: Home testing technology strategy is critical for early screening of disease.. However, current home testing technologies often require complex processes, which limits their application.. In this study, a time-resolved cascade logic gate microfluidic chip (TCLMC) was revealed to enable capillary force-based one-step operation without manual intervention or professional equipment.

other:

Article Title: Fluorescence microarrays for enzyme-free DNA detection based on web hybrid chain reaction
Article Snippet: The DNA microarray were printed by Smart Arrayer (Beijing CapitalBio Co. Ltd.) and scanned by Luxsca-10K/A microarray Scanner (532 nm laser source for Cy3, Beijing CapitalBio Co. Ltd.).



Similar Products

90
Agilent technologies g2565ca high-resolution laser microarray scanner
G2565ca High Resolution Laser Microarray Scanner, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+microarray+laser+scanner/pmc11092345-332-15-20
Average 90 stars, based on 1 article reviews
g2565ca high-resolution laser microarray scanner - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
Agilent technologies high microarray laser scanner
Down-regulation of distinct mRNAs coding for signature gamete-, ookinete- and oocyst-specific proteins in uis12(-) blood stage parasites. Shown are mean values of <t>microarray</t> results of total RNA isolated from mixed infected erythrocytes from uis12(-) (clone 1) - and WT- infected mice from two biological replicates. (A) Shown is a volcano-plot illustrating the fold change of the expression levels and the negative log p -values of all analyzed 2,890 P. berghei genes. The dotted black line represents a p -value of 0.05 and all transcripts with a p -value <0.05 are shown in red. Exemplary transcripts are highlighted and labeled in blue. (B) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among all transcripts (upper left), blood stage-specific transcripts (center), and gametocyte-specific transcripts (upper right) ( <xref ref-type=Otto et al., 2014 ). Exemplary transcripts are listed in the respective region of the chart. The number of transcripts analyzed is shown in a white circle inside the center. (C) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among female (left) and male (right) gametocyte-specific transcripts ( Yeoh et al., 2017 ). The number of transcripts analyzed is shown in a white circle inside the center. " width="250" height="auto" />
High Microarray Laser Scanner, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+microarray+laser+scanner/pmc07973279-312-16-22
Average 90 stars, based on 1 article reviews
high microarray laser scanner - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
Agilent technologies g2565ca high‐resolution laser microarray scanner
Down-regulation of distinct mRNAs coding for signature gamete-, ookinete- and oocyst-specific proteins in uis12(-) blood stage parasites. Shown are mean values of <t>microarray</t> results of total RNA isolated from mixed infected erythrocytes from uis12(-) (clone 1) - and WT- infected mice from two biological replicates. (A) Shown is a volcano-plot illustrating the fold change of the expression levels and the negative log p -values of all analyzed 2,890 P. berghei genes. The dotted black line represents a p -value of 0.05 and all transcripts with a p -value <0.05 are shown in red. Exemplary transcripts are highlighted and labeled in blue. (B) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among all transcripts (upper left), blood stage-specific transcripts (center), and gametocyte-specific transcripts (upper right) ( <xref ref-type=Otto et al., 2014 ). Exemplary transcripts are listed in the respective region of the chart. The number of transcripts analyzed is shown in a white circle inside the center. (C) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among female (left) and male (right) gametocyte-specific transcripts ( Yeoh et al., 2017 ). The number of transcripts analyzed is shown in a white circle inside the center. " width="250" height="auto" />
G2565ca High‐Resolution Laser Microarray Scanner, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/high+microarray+laser+scanner/pmc07995094-182-15-20
Average 90 stars, based on 1 article reviews
g2565ca high‐resolution laser microarray scanner - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


Down-regulation of distinct mRNAs coding for signature gamete-, ookinete- and oocyst-specific proteins in uis12(-) blood stage parasites. Shown are mean values of microarray results of total RNA isolated from mixed infected erythrocytes from uis12(-) (clone 1) - and WT- infected mice from two biological replicates. (A) Shown is a volcano-plot illustrating the fold change of the expression levels and the negative log p -values of all analyzed 2,890 P. berghei genes. The dotted black line represents a p -value of 0.05 and all transcripts with a p -value <0.05 are shown in red. Exemplary transcripts are highlighted and labeled in blue. (B) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among all transcripts (upper left), blood stage-specific transcripts (center), and gametocyte-specific transcripts (upper right) ( <xref ref-type=Otto et al., 2014 ). Exemplary transcripts are listed in the respective region of the chart. The number of transcripts analyzed is shown in a white circle inside the center. (C) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among female (left) and male (right) gametocyte-specific transcripts ( Yeoh et al., 2017 ). The number of transcripts analyzed is shown in a white circle inside the center. " width="100%" height="100%">

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

doi: 10.3389/fcimb.2021.624945

Figure Lengend Snippet: Down-regulation of distinct mRNAs coding for signature gamete-, ookinete- and oocyst-specific proteins in uis12(-) blood stage parasites. Shown are mean values of microarray results of total RNA isolated from mixed infected erythrocytes from uis12(-) (clone 1) - and WT- infected mice from two biological replicates. (A) Shown is a volcano-plot illustrating the fold change of the expression levels and the negative log p -values of all analyzed 2,890 P. berghei genes. The dotted black line represents a p -value of 0.05 and all transcripts with a p -value <0.05 are shown in red. Exemplary transcripts are highlighted and labeled in blue. (B) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among all transcripts (upper left), blood stage-specific transcripts (center), and gametocyte-specific transcripts (upper right) ( Otto et al., 2014 ). Exemplary transcripts are listed in the respective region of the chart. The number of transcripts analyzed is shown in a white circle inside the center. (C) Pie charts displaying the proportions of up- (green >2), non- (grey), and down- (orange <-2) regulated transcripts among female (left) and male (right) gametocyte-specific transcripts ( Yeoh et al., 2017 ). The number of transcripts analyzed is shown in a white circle inside the center.

Article Snippet: Scanning of the microarrays was performed with 5 µm resolution and the extended mode using a ‘High Resolution Microarray Laser Scanner’ (G2505, Agilent Technologies).

Techniques: Microarray, Isolation, Infection, Expressing, Labeling

Confirmation of down-regulation of selected mRNAs by quantitative RT-PCR. Quantitative RT-PCR on selected blood stage and gametocyte transcripts validate the results of the microarray analysis. Shown are -fold changes of steady state mRNA levels of uis12(-) clone 1 compared to wild-type mixed blood stages for selected genes ( Puf1 , P28 , MDV , DOZI , Actin II , UIS1/IK2 , SET , MSP1 , and AMA1 ). qRT-PCR data were normalized to the steady state levels of HSP70 mRNA. The microarray data represent mean values of biological replicate 1 and 2 ( ± SD).

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

doi: 10.3389/fcimb.2021.624945

Figure Lengend Snippet: Confirmation of down-regulation of selected mRNAs by quantitative RT-PCR. Quantitative RT-PCR on selected blood stage and gametocyte transcripts validate the results of the microarray analysis. Shown are -fold changes of steady state mRNA levels of uis12(-) clone 1 compared to wild-type mixed blood stages for selected genes ( Puf1 , P28 , MDV , DOZI , Actin II , UIS1/IK2 , SET , MSP1 , and AMA1 ). qRT-PCR data were normalized to the steady state levels of HSP70 mRNA. The microarray data represent mean values of biological replicate 1 and 2 ( ± SD).

Article Snippet: Scanning of the microarrays was performed with 5 µm resolution and the extended mode using a ‘High Resolution Microarray Laser Scanner’ (G2505, Agilent Technologies).

Techniques: Quantitative RT-PCR, Microarray

A motif is shared by up-regulated transcripts in uis12(-) parasites, and the comparison of dozi(-), cith(-) and uis12(-) target transcripts reveals possible overlapping functions. (A) Shown is a graphic display of the 10-nucleotide U-rich motif found in the ORF of transcripts that are up-regulated in absence of UIS12 in the microarray with biological replicate 1. The size of the depicted nucleotide represents its probability at the respective position. (B) Venn diagram comparing shared down-regulated transcripts of the gametocyte microarray analyses performed for dozi(-) and cith(-) with a -fold change lower than -1 ( <xref ref-type=Mair et al., 2010 ) and down-regulated transcripts in mixed blood stages of uis12(-) with a mean -fold change lower than -2. " width="100%" height="100%">

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Pleiotropic Roles for the Plasmodium berghei RNA Binding Protein UIS12 in Transmission and Oocyst Maturation

doi: 10.3389/fcimb.2021.624945

Figure Lengend Snippet: A motif is shared by up-regulated transcripts in uis12(-) parasites, and the comparison of dozi(-), cith(-) and uis12(-) target transcripts reveals possible overlapping functions. (A) Shown is a graphic display of the 10-nucleotide U-rich motif found in the ORF of transcripts that are up-regulated in absence of UIS12 in the microarray with biological replicate 1. The size of the depicted nucleotide represents its probability at the respective position. (B) Venn diagram comparing shared down-regulated transcripts of the gametocyte microarray analyses performed for dozi(-) and cith(-) with a -fold change lower than -1 ( Mair et al., 2010 ) and down-regulated transcripts in mixed blood stages of uis12(-) with a mean -fold change lower than -2.

Article Snippet: Scanning of the microarrays was performed with 5 µm resolution and the extended mode using a ‘High Resolution Microarray Laser Scanner’ (G2505, Agilent Technologies).

Techniques: Microarray