glua2 (Cell Signaling Technology Inc)
95
Structured Review
Cell Signaling Technology Inc
glua2
Glua2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 88 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glua2/AMPA+Receptor+2+(GluA2)+Rabbit+mAb/pm41679355-99-94-97
Average 95 stars, based on 88 article reviews
Glua2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 88 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glua2/AMPA+Receptor+2+(GluA2)+Rabbit+mAb/pm41679355-99-94-97
Average 95 stars, based on 88 article reviews
glua2 - by Bioz Stars,
2026-09
95/100 stars
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Blocking Assay:Article Title: Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats. Article Snippet: .. After blocking with 3% BSA-TBST for 1 h at room temperature, membranes were incubated overnight at 4◦C with gentle shaking with the following primary antibodies: β-actin (1:5000, AC026, ABclonal), TLR4 (1:250, PA5-23124, Invitrogen), MyD88 (1:400, sc-74532, Santa Cruz), PI3K p85 (1:1000, 4292, CST), PhosphoAkt (1:2000, 4060, CST), Akt (1:1000, 4685, CST), Phospho-NF-κB p65 (1:500, MA5-15160, Invitrogen), NF-κB p65 (1:500, 8242, CST), IL-6 (1:1000, ab9324, Abcam), TNF-α (1:1000, ab215188, Abcam), IL-1β (1:1000, ab283818, Abcam), HMGB1 (1:1000, ab79823, Abcam), Cleaved caspase-3 (1:1000, 9661, CST), caspase-1 (1:1000, 83383, CST), NR2A (1:1000, A19089, ABclonal), NR2B (1:1000, A3056, ABclonal), Article Title: Early-Life Arsenic Exposure Induces Histone H3K9 Methylation Causing PANoptosis and Neurodevelopmental Impairments in Offspring. Article Snippet: Arsenic exposure is well-established to cause neurotoxicity, but its underlying molecular mechanisms remain unclear.. This study investigates the effects of early-life arsenic exposure on the nervous system of offspring.. Female mice were exposed to NaAsO2, and alterations in learning, memory, and hippocampal lesions in offspring were assessed. Incubation:Article Title: Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats. Article Snippet: .. After blocking with 3% BSA-TBST for 1 h at room temperature, membranes were incubated overnight at 4◦C with gentle shaking with the following primary antibodies: β-actin (1:5000, AC026, ABclonal), TLR4 (1:250, PA5-23124, Invitrogen), MyD88 (1:400, sc-74532, Santa Cruz), PI3K p85 (1:1000, 4292, CST), PhosphoAkt (1:2000, 4060, CST), Akt (1:1000, 4685, CST), Phospho-NF-κB p65 (1:500, MA5-15160, Invitrogen), NF-κB p65 (1:500, 8242, CST), IL-6 (1:1000, ab9324, Abcam), TNF-α (1:1000, ab215188, Abcam), IL-1β (1:1000, ab283818, Abcam), HMGB1 (1:1000, ab79823, Abcam), Cleaved caspase-3 (1:1000, 9661, CST), caspase-1 (1:1000, 83383, CST), NR2A (1:1000, A19089, ABclonal), NR2B (1:1000, A3056, ABclonal), Article Title: Early-Life Arsenic Exposure Induces Histone H3K9 Methylation Causing PANoptosis and Neurodevelopmental Impairments in Offspring. Article Snippet: Arsenic exposure is well-established to cause neurotoxicity, but its underlying molecular mechanisms remain unclear.. This study investigates the effects of early-life arsenic exposure on the nervous system of offspring.. Female mice were exposed to NaAsO2, and alterations in learning, memory, and hippocampal lesions in offspring were assessed. Gentle:Article Title: Modulation of HMGB1-mediated neuroinflammation and synaptic plasticity by ethyl pyruvate reduces methamphetamine reward and motivation in male rats. Article Snippet: .. After blocking with 3% BSA-TBST for 1 h at room temperature, membranes were incubated overnight at 4◦C with gentle shaking with the following primary antibodies: β-actin (1:5000, AC026, ABclonal), TLR4 (1:250, PA5-23124, Invitrogen), MyD88 (1:400, sc-74532, Santa Cruz), PI3K p85 (1:1000, 4292, CST), PhosphoAkt (1:2000, 4060, CST), Akt (1:1000, 4685, CST), Phospho-NF-κB p65 (1:500, MA5-15160, Invitrogen), NF-κB p65 (1:500, 8242, CST), IL-6 (1:1000, ab9324, Abcam), TNF-α (1:1000, ab215188, Abcam), IL-1β (1:1000, ab283818, Abcam), HMGB1 (1:1000, ab79823, Abcam), Cleaved caspase-3 (1:1000, 9661, CST), caspase-1 (1:1000, 83383, CST), NR2A (1:1000, A19089, ABclonal), NR2B (1:1000, A3056, ABclonal), Virus:Article Title: β2AR as a target in methamphetamine addiction: Divergent mechanisms from TAAR1. Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies monoclonal anti-FLAG M2–fluorescein isothiocyanate antibody Sigma-Aldrich cat#F1804;RRID:AB_262044 AMPA Receptor 1 (GluA1) Antibody CST cat#13185;RRID:AB_2732897 AMPA Receptor 2 (GluA2) Antibody CST Recombinant:Article Title: β2AR as a target in methamphetamine addiction: Divergent mechanisms from TAAR1. Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies monoclonal anti-FLAG M2–fluorescein isothiocyanate antibody Sigma-Aldrich cat#F1804;RRID:AB_262044 AMPA Receptor 1 (GluA1) Antibody CST cat#13185;RRID:AB_2732897 AMPA Receptor 2 (GluA2) Antibody CST Electron Microscopy:Article Title: β2AR as a target in methamphetamine addiction: Divergent mechanisms from TAAR1. Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies monoclonal anti-FLAG M2–fluorescein isothiocyanate antibody Sigma-Aldrich cat#F1804;RRID:AB_262044 AMPA Receptor 1 (GluA1) Antibody CST cat#13185;RRID:AB_2732897 AMPA Receptor 2 (GluA2) Antibody CST Staining:Article Title: Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain. Article Snippet: Article Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain Graphical abstract Highlights • SBI-810 is a β-arrestin-2-biased allosteric modulator of neurotensin receptor 1 • Systemic or local SBI-810 injection inhibits acute and chronic pain in rodent models • SBI-810 blocks peripheral and central sensitization in DRG and spinal cord neurons • SBI-810 mitigates opioid abuse and does not impair motor and cognitive function Authors Ran Guo, Ouyang Chen, Yang Zhou, ..., William C. Wetsel, Lawrence S. Barak, Ru-Rong Ji Correspondence ru-rong.ji@duke.edu In brief SBI-810, an arrestin-biased allosteric modulator of neurotensin receptor 1, can effectively alleviate acute and chronic pain in rodent models via peripheral and central modulation and can also mitigate opioid withdrawal effects.. Guo et al., 2025, Cell 188, 4332–4349 August 7, 2025 © 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. https://doi.org/10.1016/j.cell.2025.04.038 ll |