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Broad Institute Inc gene pattern 1.3.1
Gene Pattern 1.3.1, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/genetic+pattern+search+optimization/gene+pattern+program/pmc01929138-236-7-19
Average 90 stars, based on 1 article reviews
gene pattern 1.3.1 - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Software:

Article Title: Gene expression analysis of biopsy samples reveals critical limitations of transcriptome‐based molecular classifications of hepatocellular carcinoma
Article Snippet: .. The preprocessed data were classified with the Nearest Template Prediction algorithm implementation in the Gene Pattern software (Broad Institute, Boston, MA) using published gene signatures obtained from Molecular Signatures Database . .. For pathway enrichment analysis, we applied the GSEAPreranked algorithm from the javaGSEA software version 2.0.13 (Broad Institute) .

Article Title: Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection
Article Snippet: .. Unless stated otherwise all data analysis was performed using the Genpattern software (Broad Institute) [ ]. ..

Article Title: Activation of STING in T cells induces type I IFN responses and cell death
Article Snippet: .. Adding TCR stimulation further increased expression of most ISGs, reinforcing the possibility of synergy between these pathways. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window Fig 3 caption a7 caption a8 STING activation increases B6 T cell expression of apoptosis, cell stress related genes in addition to dramatic increases in ISG expression (A) Gene pathways activated in response to TCR or TCR+DMXAA stimulation as determined using RNA sequencing data clustered based on similarity of samples using GenomePattern software (Broad Institute); (B) Changes in T cell expression of anti- and pro-apoptotic and ER stress-related genes in T cells in response to TCR or TCR+DMXAA activation; (C) STING-dependent upregulation of IFNs and selected ISGs in T cells; (D) STING-dependent activation of pro-apoptotic pathways in T cells versus macrophages. ..

Generated:

Article Title: Immune Chaperone gp96 Drives the Contributions of Macrophages to Inflammatory Colon Tumorigenesis
Article Snippet: .. Heat map was generated demonstrating differential expression of genes in the wild-type and knockout cells, using Gene Pattern program provided by the Broad Institute. ..

Article Title: Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis
Article Snippet: .. Heat map was generated demonstrating differential expression of genes in the WT and KO cells, using Gene Pattern program provided by the Broad Institute. ..

Article Title: Interleukin-17 producing γδ T cells originate from SOX13 + progenitors that are independent of γδTCR signaling
Article Snippet: .. Volcano plots showing fold change versus p-value were generated using R. Hierarchical clustering and heat maps of DEGs and differentially expressed annotated transcription factors were generated using the GenePattern program of the Broad Institute. .. Single-cell qPCR gene expression Single-cell capture, RNA preparation, reverse transcription, and preamplification were performed using a C1 auto-prep system (Fluidigm).

Quantitative Proteomics:

Article Title: Immune Chaperone gp96 Drives the Contributions of Macrophages to Inflammatory Colon Tumorigenesis
Article Snippet: .. Heat map was generated demonstrating differential expression of genes in the wild-type and knockout cells, using Gene Pattern program provided by the Broad Institute. ..

Article Title: Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis
Article Snippet: .. Heat map was generated demonstrating differential expression of genes in the WT and KO cells, using Gene Pattern program provided by the Broad Institute. ..

Knock-Out:

Article Title: Immune Chaperone gp96 Drives the Contributions of Macrophages to Inflammatory Colon Tumorigenesis
Article Snippet: .. Heat map was generated demonstrating differential expression of genes in the wild-type and knockout cells, using Gene Pattern program provided by the Broad Institute. ..

Expressing:

Article Title: Activation of STING in T cells induces type I IFN responses and cell death
Article Snippet: .. Adding TCR stimulation further increased expression of most ISGs, reinforcing the possibility of synergy between these pathways. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window Fig 3 caption a7 caption a8 STING activation increases B6 T cell expression of apoptosis, cell stress related genes in addition to dramatic increases in ISG expression (A) Gene pathways activated in response to TCR or TCR+DMXAA stimulation as determined using RNA sequencing data clustered based on similarity of samples using GenomePattern software (Broad Institute); (B) Changes in T cell expression of anti- and pro-apoptotic and ER stress-related genes in T cells in response to TCR or TCR+DMXAA activation; (C) STING-dependent upregulation of IFNs and selected ISGs in T cells; (D) STING-dependent activation of pro-apoptotic pathways in T cells versus macrophages. ..

Activation Assay:

Article Title: Activation of STING in T cells induces type I IFN responses and cell death
Article Snippet: .. Adding TCR stimulation further increased expression of most ISGs, reinforcing the possibility of synergy between these pathways. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window Fig 3 caption a7 caption a8 STING activation increases B6 T cell expression of apoptosis, cell stress related genes in addition to dramatic increases in ISG expression (A) Gene pathways activated in response to TCR or TCR+DMXAA stimulation as determined using RNA sequencing data clustered based on similarity of samples using GenomePattern software (Broad Institute); (B) Changes in T cell expression of anti- and pro-apoptotic and ER stress-related genes in T cells in response to TCR or TCR+DMXAA activation; (C) STING-dependent upregulation of IFNs and selected ISGs in T cells; (D) STING-dependent activation of pro-apoptotic pathways in T cells versus macrophages. ..

RNA Sequencing:

Article Title: Activation of STING in T cells induces type I IFN responses and cell death
Article Snippet: .. Adding TCR stimulation further increased expression of most ISGs, reinforcing the possibility of synergy between these pathways. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window Fig 3 caption a7 caption a8 STING activation increases B6 T cell expression of apoptosis, cell stress related genes in addition to dramatic increases in ISG expression (A) Gene pathways activated in response to TCR or TCR+DMXAA stimulation as determined using RNA sequencing data clustered based on similarity of samples using GenomePattern software (Broad Institute); (B) Changes in T cell expression of anti- and pro-apoptotic and ER stress-related genes in T cells in response to TCR or TCR+DMXAA activation; (C) STING-dependent upregulation of IFNs and selected ISGs in T cells; (D) STING-dependent activation of pro-apoptotic pathways in T cells versus macrophages. ..

Amplification:

Article Title: Mining genome sequencing data to identify the genomic features linked to breast cancer histopathology
Article Snippet: .. Class discovery analysis of mutated or amplified genes by unsupervised hierarchical clustering was performed using the Gene Pattern program (Broad Institute, Boston, MA) according to the online instructions. .. All tests were performed using the IBM SPSS Statistics Version 21.0 (IBM Corporation, Armonk, New York).

other:

Article Title: ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis
Article Snippet: A heat map was created using GSEA or the Gene Pattern program (Broad Institute).



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