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Iobion Informatics microarray expression data
Genes identified in our <t> microarray data </t> and other.
Microarray Expression Data, supplied by Iobion Informatics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/expression+microarrays/microarray+expression+data/pmc02645904-272-19-24
Average 90 stars, based on 1 article reviews
microarray expression data - by Bioz Stars, 2026-10
90/100 stars

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1) Product Images from "Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line"

Article Title: Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line

Journal: Molecular Vision

doi:

Genes identified in our  microarray data  and other.
Figure Legend Snippet: Genes identified in our microarray data and other.

Techniques Used: Microarray, Membrane

Genes identified in our  microarray  and compared with other data.
Figure Legend Snippet: Genes identified in our microarray and compared with other data.

Techniques Used: Microarray, Binding Assay

Schematic representations of potential signaling pathways involved in serum-deprived retinal ganglion cell-5 cells. Pathways were identified by incorporating the microarray results (differentially expressed genes identified at 8, 24, 48, and 96 h of serum deprivation) into PathwayAssist software. The pathway connects the proteins (blue color) and cell processes together. Three major biological processes of cell survival, apoptosis, and DNA fragmentation, regulated by these genes are represented by yellow color squares.
Figure Legend Snippet: Schematic representations of potential signaling pathways involved in serum-deprived retinal ganglion cell-5 cells. Pathways were identified by incorporating the microarray results (differentially expressed genes identified at 8, 24, 48, and 96 h of serum deprivation) into PathwayAssist software. The pathway connects the proteins (blue color) and cell processes together. Three major biological processes of cell survival, apoptosis, and DNA fragmentation, regulated by these genes are represented by yellow color squares.

Techniques Used: Protein-Protein interactions, Microarray, Software

The biological pathway of the differentially expressed genes at 24, 48, and 96 h serum deprivation. A : Genes downregulated by serum deprivation (blue color). B : Genes upregulated by serum deprivation (violet color). The pathway was constructed on PathwayAssist software by searching for the shortest path to connect the genes of interest by other genes or cell processes with which they interacted through expression or regulation only. Each of these additional nodes has documented relation to apoptosis. The genes highlighted in blue color are the genes identified by microarray analysis, and the genes in red ovals diamonds color are the potential target genes identified with the aid of PathwayAssist.
Figure Legend Snippet: The biological pathway of the differentially expressed genes at 24, 48, and 96 h serum deprivation. A : Genes downregulated by serum deprivation (blue color). B : Genes upregulated by serum deprivation (violet color). The pathway was constructed on PathwayAssist software by searching for the shortest path to connect the genes of interest by other genes or cell processes with which they interacted through expression or regulation only. Each of these additional nodes has documented relation to apoptosis. The genes highlighted in blue color are the genes identified by microarray analysis, and the genes in red ovals diamonds color are the potential target genes identified with the aid of PathwayAssist.

Techniques Used: Construct, Software, Expressing, Microarray

Biological pathway for the differentially expressed neuronal cell death genes in serum-deprived retinal ganglion cells. Pathways were identified by incorporating the microarray results (genes which are differentially expressed at 24, 48, and 96 h) into the Pathway Assit software. The pathway was constructed on this software by searching for the shortest path to connect the genes of interest by other genes or cell processes with which they interacted through expression or regulation only. Three major biologic processes are identified (apoptosis, death, and DNA fragmentation) and are represented by yellow rectangles. Blue ovals denote genes identified as neuronal cell death, and red ovals new genes connected to this pathway.
Figure Legend Snippet: Biological pathway for the differentially expressed neuronal cell death genes in serum-deprived retinal ganglion cells. Pathways were identified by incorporating the microarray results (genes which are differentially expressed at 24, 48, and 96 h) into the Pathway Assit software. The pathway was constructed on this software by searching for the shortest path to connect the genes of interest by other genes or cell processes with which they interacted through expression or regulation only. Three major biologic processes are identified (apoptosis, death, and DNA fragmentation) and are represented by yellow rectangles. Blue ovals denote genes identified as neuronal cell death, and red ovals new genes connected to this pathway.

Techniques Used: Microarray, Software, Construct, Expressing

Comparative evaluation of microarray and real-time RT-PCR results. Twelve genes, identified as differentially expressed in gene arrays and regulated in response to time-dependent serum deprivation, were evaluated with RT-PCR. Values on the y-axis represent the fold change derived from the mean expression value for each gene, and values on the x-axis represent the time course of RGC-5 serum deprivation. Total RNA isolated from these cells was used for both microarray analysis and real-time RT-PCR. The closed circles (rectangle) represent microarray results, whereas the closed squares (circle) represent the quantitative RT-PCR data.
Figure Legend Snippet: Comparative evaluation of microarray and real-time RT-PCR results. Twelve genes, identified as differentially expressed in gene arrays and regulated in response to time-dependent serum deprivation, were evaluated with RT-PCR. Values on the y-axis represent the fold change derived from the mean expression value for each gene, and values on the x-axis represent the time course of RGC-5 serum deprivation. Total RNA isolated from these cells was used for both microarray analysis and real-time RT-PCR. The closed circles (rectangle) represent microarray results, whereas the closed squares (circle) represent the quantitative RT-PCR data.

Techniques Used: Microarray, Quantitative RT-PCR, Reverse Transcription Polymerase Chain Reaction, Derivative Assay, Expressing, Isolation

Related Articles

Microarray:

Article Title: Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line
Article Snippet: .. To identify potential signaling and pathways and gene-regulatory networks that are associated with retinal ganglion cell death,we imported the microarray expression data to PathwayAssist (Iobion, Informatics, LLC). ..

Expressing:

Article Title: Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line
Article Snippet: .. To identify potential signaling and pathways and gene-regulatory networks that are associated with retinal ganglion cell death,we imported the microarray expression data to PathwayAssist (Iobion, Informatics, LLC). ..



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Image Search Results


Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Flowchart of the study design. Genomic and transcriptomic data were extracted from the GEO database ( GSE83448 ).

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Differentially expressed S-palmitoylation-related genes in 39 CD intestinal biopsies and 14 healthy controls. (A) PCA for GSE83448 . (B) Volcano plot illustrating 3743 DEGs. (C) Venn diagram depicting the overlap between DEGs and S-palmitoylation-related genes. (D) Heatmap representing the 23 SP-DEGs in CD and healthy controls. (E) Boxplots comparing the 23 SP-DEGs in CD and healthy controls. Abbreviations: CD: Crohn’s disease; PCA: Principal component analysis; DEGs: Differentially expressed genes; SP-DEGs: S-palmitoylation-related differentially expressed genes.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques:

Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Journal: Biomolecules and Biomedicine

Article Title: S-palmitoylation-related genes in Crohn’s disease: Bioinformatic identification and validation

doi: 10.17305/bb.2025.13221

Figure Lengend Snippet: Functional enrichment analysis of SP-DEGs in the GSE83448 dataset. (A) The bubble plot illustrates key enriched terms across various categories. BP denotes biological processes; CC indicates cellular components; and MF represents molecular functions. (B) The circle map emphasizes BPs associated with S-palmitoylation. (C) The bar plot presents the results of the functional enrichment analysis, ranked by statistical significance. (D) The Circos plot visualizes the functional associations across categories. Abbreviations: SP-DEGs: S-palmitoylation-related differentially expressed genes; BP: Biological process; CC: Cellular component; MF: Molecular function.

Article Snippet: The gene expression microarray dataset GSE83448 was obtained from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO; https://www.ncbi.nlm.nih.gov/geo/ ) [ ].

Techniques: Functional Assay