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encode arrays  (NimbleGen Systems GmbH)

 
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    Structured Review

    NimbleGen Systems GmbH encode arrays
    Encode Arrays, supplied by NimbleGen Systems GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/encode/encode+arrays/pmc02448833-248-11-12
    Average 90 stars, based on 1 article reviews
    encode arrays - by Bioz Stars, 2026-10
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    Related Articles

    Immunoprecipitation:

    Article Title: N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    Article Snippet: .. Immunoprecipitated chromatin fragments were amplified using the Whole Genome Amplification kit (Sigma) for 2 × 14 cycles, purified, then checked for enrichment over control IgG and total samples before sending for probing of the ENCODE array (Nimblegen Systems). ..

    Amplification:

    Article Title: N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    Article Snippet: .. Immunoprecipitated chromatin fragments were amplified using the Whole Genome Amplification kit (Sigma) for 2 × 14 cycles, purified, then checked for enrichment over control IgG and total samples before sending for probing of the ENCODE array (Nimblegen Systems). ..

    Whole Genome Amplification:

    Article Title: N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    Article Snippet: .. Immunoprecipitated chromatin fragments were amplified using the Whole Genome Amplification kit (Sigma) for 2 × 14 cycles, purified, then checked for enrichment over control IgG and total samples before sending for probing of the ENCODE array (Nimblegen Systems). ..

    Purification:

    Article Title: N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    Article Snippet: .. Immunoprecipitated chromatin fragments were amplified using the Whole Genome Amplification kit (Sigma) for 2 × 14 cycles, purified, then checked for enrichment over control IgG and total samples before sending for probing of the ENCODE array (Nimblegen Systems). ..

    Control:

    Article Title: N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    Article Snippet: .. Immunoprecipitated chromatin fragments were amplified using the Whole Genome Amplification kit (Sigma) for 2 × 14 cycles, purified, then checked for enrichment over control IgG and total samples before sending for probing of the ENCODE array (Nimblegen Systems). ..

    other:

    Article Title: Identification of genes directly regulated by the oncogene ZNF217 using ChIP-chip assays
    Article Snippet: ENCODE and promoter arrays were produced by NimbleGen Systems, Inc (Madison, WI).

    Article Title: CTCF physically links cohesin to chromatin
    Article Snippet: The amplification and preparation of immunoprecipitated DNA for hybridizations to ENCODE arrays (NimbleGen Systems) were performed essentially as described in ref. 46 with minor modifications at DNA preparation and purification steps.



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    Image Search Results


    Schematic of constructing engineered Y. lipolytica strain for squalene production. I indicate lipid droplet engineering to modulate triacylglycerols synthesis and increase squalene storage capacity. II indicates modulation of the MVA pathway to promote squalene synthesis flux. III indicates enzyme fusion engineering to promote catalytic efficiency between ERG20 and SQS. IV indicates iterative copy numbering of the ScHMG1 gene. V indicates adaptive evolutionary engineering strategies. Red font represents endogenous genes, and blue font represents heterologous genes. DGA1, Diacylglycerol acyltransferase; LRO1, Phospholipid: diacylglycerol acyltransferase; ERG10, Acetyl-CoA acetyltransferase; ERG13, HMG-CoA synthase; ScHMG1, 3-hydroxy-3-methyl glutaryl coenzyme A reductase of S. cerevisiae origin; ERG20, farnesyl diphosphate synthase; SQS, squalene synthase.

    Journal: Synthetic and Systems Biotechnology

    Article Title: Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica

    doi: 10.1016/j.synbio.2026.01.017

    Figure Lengend Snippet: Schematic of constructing engineered Y. lipolytica strain for squalene production. I indicate lipid droplet engineering to modulate triacylglycerols synthesis and increase squalene storage capacity. II indicates modulation of the MVA pathway to promote squalene synthesis flux. III indicates enzyme fusion engineering to promote catalytic efficiency between ERG20 and SQS. IV indicates iterative copy numbering of the ScHMG1 gene. V indicates adaptive evolutionary engineering strategies. Red font represents endogenous genes, and blue font represents heterologous genes. DGA1, Diacylglycerol acyltransferase; LRO1, Phospholipid: diacylglycerol acyltransferase; ERG10, Acetyl-CoA acetyltransferase; ERG13, HMG-CoA synthase; ScHMG1, 3-hydroxy-3-methyl glutaryl coenzyme A reductase of S. cerevisiae origin; ERG20, farnesyl diphosphate synthase; SQS, squalene synthase.

    Article Snippet: The 3-hydroxy-3-methylglutaryl-CoA reductase encoding gene ScHMG1 (GenBank ID: 854900) from S. cerevisiae was codon-optimized and synthesized (Genewiz, Suzhou, China).

    Techniques:

    Enhancing the expression of ScHMG1 to boost squalene synthesis . (A) Schematic design of overexpressing ScHMG1 at the IntC locus. (B) Effects of enhanced ScHMG1 expression on squalene and lipid synthesis in the engineered Y. lipolytica strain. (C) The pH, biomass, and glucose consumption of the engineered strains after 72 h of fermentation.

    Journal: Synthetic and Systems Biotechnology

    Article Title: Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica

    doi: 10.1016/j.synbio.2026.01.017

    Figure Lengend Snippet: Enhancing the expression of ScHMG1 to boost squalene synthesis . (A) Schematic design of overexpressing ScHMG1 at the IntC locus. (B) Effects of enhanced ScHMG1 expression on squalene and lipid synthesis in the engineered Y. lipolytica strain. (C) The pH, biomass, and glucose consumption of the engineered strains after 72 h of fermentation.

    Article Snippet: The 3-hydroxy-3-methylglutaryl-CoA reductase encoding gene ScHMG1 (GenBank ID: 854900) from S. cerevisiae was codon-optimized and synthesized (Genewiz, Suzhou, China).

    Techniques: Expressing