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Structured Review

Ferring Pharmaceuticals computer-generated randomisation
Cabar 2008
Computer Generated Randomisation, supplied by Ferring Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/computer+generated+randomisation+lists/computer+generated+randomisation/pmc11086629-136-13-10
Average 90 stars, based on 1 article reviews
computer-generated randomisation - by Bioz Stars, 2026-11
90/100 stars

Images

1) Product Images from "Oxytocin receptor antagonists for inhibiting preterm labour"

Article Title: Oxytocin receptor antagonists for inhibiting preterm labour

Journal: The Cochrane Database of Systematic Reviews

doi: 10.1002/14651858.CD004452.pub3

Cabar 2008
Figure Legend Snippet: Cabar 2008

Techniques Used: Control, Activity Assay, Sequencing, Selection

European 2001
Figure Legend Snippet: European 2001

Techniques Used: Control, Injection, Sequencing, Selection

French/Australian 2001
Figure Legend Snippet: French/Australian 2001

Techniques Used: Infection, Control, Injection, Sequencing, Selection

Goodwin 1994
Figure Legend Snippet: Goodwin 1994

Techniques Used: Control, Sequencing, Selection, Blocking Assay, Introduce

Goodwin 1996
Figure Legend Snippet: Goodwin 1996

Techniques Used: Infection, Control, Sequencing, Selection, Introduce

Kashanian 2005
Figure Legend Snippet: Kashanian 2005

Techniques Used: Control, Sequencing, Selection, Blocking Assay

Lin 2009
Figure Legend Snippet: Lin 2009

Techniques Used: Infection, Saline, Control, Sequencing, Selection

Moutquin 2000
Figure Legend Snippet: Moutquin 2000

Techniques Used: Infection, Control, Sequencing, Selection, Blocking Assay

Nonnenmacher 2009
Figure Legend Snippet: Nonnenmacher 2009

Techniques Used: Injection, Control, Sequencing, Selection

Richter 2005
Figure Legend Snippet: Richter 2005

Techniques Used: Injection, Control, Saline, Infection, Inhibition, Sequencing, Selection

Romero 2000
Figure Legend Snippet: Romero 2000

Techniques Used: Infection, Control, Sequencing, Selection, Modification

Salim 2012
Figure Legend Snippet: Salim 2012

Techniques Used: Biomarker Discovery, Control, Sequencing, Selection

Shim 2006
Figure Legend Snippet: Shim 2006

Techniques Used: Infection, Clinical Proteomics, Control, Injection, Comparison, Sequencing, Selection

Thornton 2009
Figure Legend Snippet: Thornton 2009

Techniques Used: Coagulation, Control, Clinical Proteomics, Concentration Assay, Comparison, Sequencing, Selection, Generated

Related Articles

Sequencing:

Article Title: Carbetocin for preventing postpartum haemorrhage
Article Snippet: .. Notes The project was supported by Ferring Pharmaceuticals Ltd. Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Method of randomisation: computer‐generated randomisation code. ..

Selection:

Article Title: Carbetocin for preventing postpartum haemorrhage
Article Snippet: .. Notes The project was supported by Ferring Pharmaceuticals Ltd. Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Method of randomisation: computer‐generated randomisation code. ..

Article Title: Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
Article Snippet: Dose-adjustment was not permitted in the individualised dosing arm Outcomes Reported in paper: live birth, ongoing pregnancy, clinical pregnancy, number of oocytes, total dose of FSH, duration of FSH, multiple pregnancy, moderate and severe OHSS, had at least 1 transferable embryo, normal response to stimulation Obtained from author correspondence*: cycle cancellations for poor and hyper-response Not available: severe OHSS, poor response, hyper-response (this data was available only in participant subgroups, and authors declined to provide the non-stratified data) Notes Trial registration: NCT01956110, prospectively Funding: Ferring Pharmaceuticals Conflict of interest: many investigators have received grants or are employed by Industry Presented in part at the 32nd Annual Meeting of the European Society of Human Reproduction and Embryology, July 3-6, 2016, Helsinki, Finland Email correspondence undertaken: yes with Ferring staff; however, not all requested information was provided (Helmgaard 2017b [pers comm]) *indicates information obtained from email correspondence Risk of bias Bias Authors’ judgement Support for judgement Random sequence generation (selection bias) Low risk Paper states “Women were randomly assigned in a 1:1 ratio via a central computer-generated randomization sequence, prepared by an independent statistician. .. Randomization was stratified by age (< 35, 35-37, and 38-40 years) and performed in blocks of four within trial sites.” Allocation concealment (selection bias) Low risk No description in the paper; however, correspondence with Ferring reveals that the randomisation allocation was concealed within the computer programme until the time of randomisation. ..

Article Title: Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
Article Snippet: Random sequence generation (selection bias) , Low risk , Paper states "Women were randomly assigned in a 1:1 ratio via a central computer‐generated randomization sequence, prepared by an independent statistician. Randomization was stratified by age (< 35, 35–37, and 38–40 years) and performed in blocks of four within trial sites.". .. Allocation concealment (selection bias) , Low risk , No description in the paper; however, correspondence with Ferring reveals that the randomisation allocation was concealed within the computer programme until the time of randomisation. The unblinded study nurse managed the randomisation as the other investigators were unaware of the trial allocations*. ..

Article Title: Oxytocin receptor antagonists for inhibiting preterm labour
Article Snippet: Random sequence generation (selection bias) , Low risk , "Computer‐generated randomisation lists for each center was used to allocate women to study treatment and women were stratified by gestational age at enrolment." The review authors consider this approach low risk.. .. Allocation concealment (selection bias) , Low risk , Prepared by Ferring Pharmaceuticals: computer‐generated randomisation stratified by GA and centre, supplied to pharmacists at each centre in pre‐randomised boxes labelled with country code and case number.. ..

Article Title: Oxytocin receptor antagonists for inhibiting preterm labour
Article Snippet: .. Allocation concealment (selection bias) Low risk Prepared by Ferring Pharmaceuticals: computer‐generated randomisation stratified by GA and centre, supplied to pharmacists at each centre in pre‐randomised boxes labelled with country code and case number. ..

other:

Article Title: Tocolytics for delaying preterm birth: a network meta-analysis (0924)
Article Snippet: No COI Funded by Ferring Pharmaceuticals Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk Randomised using computer-generated randomisation lists and stratified by GA (≤ 28 weeks and > 28 weeks) Allocation concealment (selection bias) Unclear risk NR Blinding of participants and personnel (performance bias) All outcomes Low risk Double-blind.

Article Title: Oxytocin receptor antagonists for inhibiting preterm labour
Article Snippet: Published by John Wiley & Sons, Ltd. European 2001 (Continued) Allocation concealment (selection bias) Low risk Prepared by Ferring Pharmaceuticals: computer-generated randomisation stratified by GA and centre, supplied to pharmacists at each centre in pre-randomised boxes labelled with country code and case number Blinding of participants and personnel (performance bias) All outcomes Low risk “Through the use of a double-blind, double-dummy technique, the utmost effort was made to keep the study blinded.

Article Title: Oxytocin receptor antagonists for inhibiting preterm labour
Article Snippet: Allocation concealment (selection bias) Low risk Prepared by Ferring Pharmaceuticals: computer-generated randomisation stratified by GA and centre, supplied to pharmacists at each centre in pre-randomised boxes labelled with country code and case number Blinding of participants and personnel (performance bias) All outcomes Low risk “Through the use of a double-blind, double-dummy technique, the utmost effort was made to keep the study blinded.



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