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Dassault Systemes cdocker module
Cdocker Module, supplied by Dassault Systemes, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdocker+molecular+docking+algorithm/cdocker+module/pm41736035-164-23-30
Average 86 stars, based on 1 article reviews
cdocker module - by Bioz Stars, 2026-09
86/100 stars

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Article Title: A novel molecule ZYZ329 targeting histone methyltransferase SMYD3 suppresses pathological angiogenesis via the driven mitochondrial ROS/HIF-1α/VEGFA axis.
Article Snippet: .. To determine molecule selectivity, the optimal binding mode and interaction of ZYZ329 with SMYD3 protein were assessed by molecular docking techniques using the CDOCKER module of Discovery Studio version 4.5 (Dassault Systemes BIOVIA) software. ..

Article Title: A novel molecule ZYZ329 targeting histone methyltransferase SMYD3 suppresses pathological angiogenesis via the driven mitochondrial ROS/HIF-1α/VEGFA axis
Article Snippet: .. To determine binding affinity, the optimal binding mode and interaction of ZYZ329 with SMYD3 protein were assessed by molecular docking techniques using the CDOCKER module of Discovery Studio version 4.5 (Dassault Systemes BIOVIA) software. ..

Software:

Article Title: Hesperidin Attenuates Chronic Stress-Induced Depression via 5-HT2A-Linked Modulation of Neurochemical, Oxidative, and Inflammatory Pathways: Experimental and In Silico Evidence.
Article Snippet: 1 Chitkara College of Pharmacy, Chitkara University, Punjab, India 2 Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India 3 Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A&M Health Science Center, College Station, TX 77807, USA 4 Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia 5 Department of Pharmaceutics, College of Pharmacy, King Saud University, 11451 Riyadh, Saudi Arabia Abstract Depression is associated with monoaminergic dysregulation, oxidative stress, and neuroinflammation, with the 5-hydroxytryptamine 2 A (5-HT2A) receptor playing a key role.. The present study investigated the antidepressant-like potential of hesperidin (HSP), a citrus-derived flavonoid, administered chronically (100 or 200 mg/kg, orally once daily for 21 days) in mice exposed to chronic unpredictable mild stress (CUMS).. These effects were further explored through 5-HT2Aassociated neurochemical and molecular mechanisms, highlighting its role in stress-related neuroprotection.



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