built-in formulation (COMSOL Inc)
90
Structured Review
COMSOL Inc
built-in formulation
Built In Formulation, supplied by COMSOL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/built-in+algorithm/built+in+algorithm/pmc04765901-43-11-9
Average 90 stars, based on 1 article reviews
Built In Formulation, supplied by COMSOL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/built-in+algorithm/built+in+algorithm/pmc04765901-43-11-9
Average 90 stars, based on 1 article reviews
built-in formulation - by Bioz Stars,
2026-10
90/100 stars
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other:Article Title: Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy. Article Snippet: The plasmonic properties of metallodielectric nanoparticles exhibit a highly sensitive dependence on geometry, due to the interaction between primitive plasmon modes associated with the surfaces of the nanoparticle.. Changes in nanoparticle geometry that reduce symmetry alter the interactions between plasmon modes and give rise to modified, and altogether new, plasmonic features.. Here, we have examined the nearand far-field optical properties of three variants of a core–shell nanoparticle: nanoshells, nanoeggs and nanocups. Article Title: Microfluidic Devices with Templated Regular Macroporous Structures for HIV Viral Capture Article Snippet: Drag force and Brownian force were introduced using the Article Title: Nonequilibrium Dynamics of Transient Autoelectrophoresis and Effect of Surface Heterogeneity. Article Snippet: Nonuniform proton flux around a reactive Janus particle as a result of zone selective heterogeneous surface reaction leads to the formation of asymmetric electrical double layers (EDLs) which assists in generating a proximate electric field dipole around the Janus particle to initiate autoelectrophoretic migration.. To estimate the force of the autoelectrophoretic motion of such Janus particles, a mathematical model is set up taking Poisson−Nernst−Plank (PNP) equations coupled with the Navier−Stokes (NS) equations with appropriate boundary conditions.. To track the actual motion of these particles, we employ moving deforming mesh and fluid−structure interactions (fsi) of COMSOL Multiphysics while a finite element method is deployed for solving the set of modeled equations. Article Title: The potential of hydrophobic membranes in enabling the operation of lithium-air batteries with ambient air Article Snippet: Article Title: High-performance nanosensors based on plasmonic Fano-like interference: probing refractive index with individual nanorice and nanobelts. Article Snippet: U nlike those propagating at metal/ dielectric interfaces, 3 localized collective oscillations of charges confined to the surface of metal nanoparticles can be directly excited by external illumination without the need of any additional coupling-in technique, provided that particles are much smaller than the incident wavelength.. These oscillations, which can be pictured as a “wave” of electrons moving across the surface of the particle, are referred to as localized surface plasmon resonances (LSPRs), and they are responsible for nanoparticles' bright colors when in colloidal suspension, as a result of their intense absorbing and scattering of light in the visible range.. One of the most appealing properties of LSPRs is that their resonant frequency strongly depends on nanoparticles' size, shape, and composition, as well as on the refractive index of the surrounding medium. Article Title: Engineering gold nanoworms with tunable longitudinal plasmon peak in the near infrared and their refractive index sensing properties Article Snippet: The computational space was discretized into a Article Title: Microfluidic devices with templated regular macroporous structures for HIV viral capture Article Snippet: The Drag force and Brownian force were introduced using the |
![XMT-2056 elicits potent antigen-dependent and Fc-R–mediated activation of monocytes in cocultures. A, Schematic of the XMT-2056 mechanism, which includes <t>HER2-dependent</t> ADC uptake into tumor cells and Fcγ-R–expressing myeloid cells. B, Chemical structure of XMT-2056. C, Cytokine induction as measured by a multiplex Luminex assay from supernatants of fresh human WBCs treated for 6 (IFN-β) or 24 (CXCL10, IL-6, and TNF-a) hours. Bars represent mean value of n = 2 data points shown as symbols. D, Competition with trastuzumab by biolayer interferometry (Octet): trastuzumab was loaded onto the sensor chip, and HER2 ECD or HT19 antibody associations are indicated by blue arrows. Additional binding by HT19 indicates noncompetitive binding. E, Competition with trastuzumab by cell-based flow cytometry. HT19 hIgG1 or mIgG2a formats detected with either Alexa Fluor anti-hIgG1 (h647) or Alexa Fluor anti-mIgG2a (m647) secondary antibodies in the presence or absence of trastuzumab–mIgG2a. Each point represents the mean and SD ( n = 3). F, Binding of XMT-2056 or HT19 antibody to HCC1954 cells showing fluorescence intensities measured by flow cytometry. Each point represents the mean and SD ( n = 2). G, CXCL10 cytokine induction in HCC1954 monocultures treated for 24 hours with XMT-2056, nonbinding control ADC, HT19, or the free payload. Each point represents the mean and SD ( n = 2). H, Binding of XMT-2056 or Fc-mutant XMT-2056, HT19, and nonbinding control ADC to SKOV3 cells showing fluorescence intensities measured by flow cytometry. Each point represents the mean and SD ( n = 3). I and J, IRF3 reporter activity of THP1 cells in coculture with SKOV3 cells ( I ) or cultured on recombinant HER2 antigen-coated plates ( J ) treated for 24 hours with XMT-2056 or Fc-mutant XMT-2056, nonbinding control ADC, or STING agonist payload. Each point represents the mean and SD ( n = 3). When noted, EC 50 and B max values represent mean of two independent experiments. gMFI, geometric mean fluorescence intensity; RLU, relative light units. ( A, Created in BioRender. Cetinbas, N. [2025], https://BioRender.com/s16c825 ; G, Created in BioRender. Cetinbas, N. [2025], https://BioRender.com/s16c825 ; I and J, Created in BioRender. Cetinbas, N. [2025], https://BioRender.com/s16c825 .)](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_0966/pmc12010966/pmc12010966__ccr-24-2449_f1.jpg)
![XMT-2056 induces killing of HER2-high and HER2-low cancer cells and induces concomitant immune-mediated killing of HER2-negative cancer cells in vitro . A and B, Cancer cell death induced by XMT-2056, nonbinding control ADC, or STING agonist payload, shown as percent viable SKBR3–NR ( A ) or MDA-MB-175-VII–NR ( B ) cells in PBMC coc ultures (84 hours time point). Each point represents the mean and SD ( n = 3). C and D , Cytokine induction by XMT-2056, nonbinding control ADC, or STING agonist payload in supernatants of SKBR3–NR ( C ) or MDA-MB-175-VII–NR ( D ) cells in PBMC cocultures (24 hours time point). Each point represents the mean and SD ( n = 3). Note that the y-axis scales vary. E, Schematic of concomitant antigen-dependent, immune-mediated killing of HER2-negative cancer cells. F, Flow cytometry of HER2 expression on SKBR3 and nuclear red expressing MDA-MB-231–NR. Each point represents the mean and SD ( n = 4). G, Cancer cell death mediated by XMT-2056, nonbinding control ADC, or STING agonist payload, shown as percent viable MDA-MB-231–NR cells in coculture with PBMCs and HER2-positive SKBR3 at the indicated ratios or in the absence of SKBR3 (84 hours time point). Each point represents the mean and SD ( n = 3). ( E, Created in BioRender. Cetinbas, N. [2025], https://BioRender.com/k38t564 .)](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_0966/pmc12010966/pmc12010966__ccr-24-2449_f2.jpg)
![Combination of XMT-2056 with immune checkpoint inhibitor anti–PD-1 elicits tumor clearance and immunologic memory in the EMT-6–rHER2 syngeneic model. A, Normalized counts for PD-L1 human mRNA and mouse mRNA in SKOV3 xenograft tumors. B, Study design including efficacy and rechallenge. Tumor implantations are indicated by circles on the left and right flanks of the mice. C, BALB/c immune-competent mice bearing syngeneic EMT-6–rHER2 engineered tumors were treated with XMT-2056 surrogate ADC targeting rat HER2, anti-mouse PD-1 (clone RPM1-14), or the indicated combinations. The ADCs were administered as single doses, whereas the mouse anti–PD-1 was administered twice weekly for 2 weeks, as indicated by the red triangles. Each point represents the mean tumor volume and SEM ( n = 10). D, Tumor-free animals from the XMT-2056 surrogate ADC (blue) and the combination (green) groups were implanted with EMT-6 parental cells on the left flank (opposite the original EMT-6–rHER2 implantation) and CT26 cells on the right flank. Age-matched untreated mice were included as controls. Right, tumor growth in individual mice in each group after implantation on day 0 plotted relative to age-matched naïve mice. CR, complete response; LF, left flank; RF, right flank. ( B, Created in BioRender. Cetinbas, N. [2025], https://BioRender.com/k61r850 .)](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_0966/pmc12010966/pmc12010966__ccr-24-2449_f6.jpg)