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Promega nanoluc binary (nanobit) split luciferase
Nanoluc Binary (Nanobit) Split Luciferase, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/binary/nanoluc+binary++nanobit++split+luciferase/pmc11861568-167-9-3
Average 90 stars, based on 1 article reviews
nanoluc binary (nanobit) split luciferase - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Luciferase:

Article Title: In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1.
Article Snippet: Cancer-specific metabolic alterations hyperactivate the kinase activity of the mammalian/mechanistic target of rapamycin (mTOR) for overcoming stressful environments.. Rapalogs, which allosterically inhibit mTOR complex 1 (mTORC1), have been approved as anticancer agents.. However, the immunosuppressive side effect of these compounds results in the promotion of tumor metastasis, thereby limiting their therapeutic efficacy.

Protein-Protein interactions:

Article Title: In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1.
Article Snippet: Cancer-specific metabolic alterations hyperactivate the kinase activity of the mammalian/mechanistic target of rapamycin (mTOR) for overcoming stressful environments.. Rapalogs, which allosterically inhibit mTOR complex 1 (mTORC1), have been approved as anticancer agents.. However, the immunosuppressive side effect of these compounds results in the promotion of tumor metastasis, thereby limiting their therapeutic efficacy.

Incubation:

Article Title: In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1.
Article Snippet: Cancer-specific metabolic alterations hyperactivate the kinase activity of the mammalian/mechanistic target of rapamycin (mTOR) for overcoming stressful environments.. Rapalogs, which allosterically inhibit mTOR complex 1 (mTORC1), have been approved as anticancer agents.. However, the immunosuppressive side effect of these compounds results in the promotion of tumor metastasis, thereby limiting their therapeutic efficacy.

other:

Article Title: Luminescent sensing of conformational integrin activation in living cells.
Article Snippet: We selected the Promega NanoLuc Binary Technology (NanoBiT) split luciferase formed by a large (LgBiT) and a small (SmBiT) subunit as an enzymatic tag, which has an extremely low self-association affinity but is able to reconstitute the catalytically active NanoBiT luciferase enzyme and brightly luminesce when brought into close proximity26 (Figure 1B).

Article Title: Luminescent sensing of conformational integrin activation in living cells
Article Snippet: We selected the Promega NanoLuc Binary Technology (NanoBiT) split luciferase formed by a large (LgBiT) and a small (SmBiT) subunit as an enzymatic tag, which has an extremely low self-association affinity but is able to reconstitute the catalytically active NanoBiT luciferase enzyme and brightly luminesce when brought into close proximity ( B).



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