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Sagmeister Inc recombinant fed-batch processes
Recombinant Fed Batch Processes, supplied by Sagmeister Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/batch+processing/recombinant+fed+batch+processes/pm29159587-217-24-9
Average 90 stars, based on 1 article reviews
recombinant fed-batch processes - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Genetically-encoded biosensors for monitoring cellular stress in bioprocessing.
Article Snippet: Wechselberger P, Sagmeister P, Herwig C: Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes.

Article Title: Soft-sensor assisted dynamic investigation of mixed feed bioprocesses
Article Snippet: Recombinant mixed feed bioprocesses are characterized by the controlled feeding of multiple defined carbon sources aiming at increased productivities.. However, mixed feed process design is challenging due to physiological constraints such as adaptation times and catabolite repression.. A novel soft-sensor assisted dynamic method that allows the science-based process design with respect to co-utilization of primary and secondary substrate was developed.

Article Title: A novel nicotinamide adenine dinucleotide control strategy for increasing the cell density of Haemophilus parasuis.
Article Snippet: Haemophilus parasuis is the causative agent of Glässer’s disease and is a major source of economic losses in the swine industry each year.. To enhance the production of an inactivated vaccine against H. parasuis, the availability of nicotinamide adenine dinucleotide (NAD) must be carefully controlled to ensure a sufficiently high cell density of H. parasuis.. In the present study, the real-time viable cell density of H. parasuis was calculated based on the capacitance of the culture.

Article Title: Teaching an old pET new tricks: tuning of inclusion body formation and properties by a mixed feed system in E. coli.
Article Snippet: Microbiol Mol Biol Rev 67(4):475–490. https://doi. org/10.1128/MMBR.67.4.475-490.2003 Wechselberger P, Sagmeister P, Herwig C (2013) Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes.

Article Title: Control of specific growth rate for the enhanced production of human interferon α2b in glycoengineered Pichia pastoris : process analytical technology guided approach
Article Snippet: BACKGROUND Process variability in bioprocess systems involving genetically engineered strains is a common bottleneck and a real-time insight of the on-going process is crucial to achieve the desired product and its quality.. In this study, a process analytical technology (PAT) platform was developed for the monitoring and control of specific growth rate during methanol induction phase (μmet) of glycoengineered Pichia pastoris fermentation for human interferon alpha 2b production.

Article Title: Mini‐review: soft sensors as means for <scp>PAT</scp> in the manufacture of bio‐therapeutics
Article Snippet: 45 Wechselberger P, Sagmeister P and Herwig C, Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes.



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