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Integral Molecular Inc membrane proteome array (mpa)
Membrane Proteome Array (Mpa), supplied by Integral Molecular Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/array+membranes/membrane+proteome+array++mpa++platform/pm40275251-75-0-8
Average 90 stars, based on 1 article reviews
membrane proteome array (mpa) - by Bioz Stars, 2026-09
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Article Title: A preclinical study of allogeneic CD19 chimeric antigen receptor double-negative T cells as an off-the-shelf immunotherapy drug against B-cell malignancies.
Article Snippet: Membrane proteome array (MPA) screening was conducted by Integral Molecular, Inc. (Shanghai, China).

Article Title: Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer
Article Snippet: Integral Molecular, Inc. (Philadelphia, PA) performed specificity testing of IgG1 F12 using the Membrane Proteome Array (MPA) platform, in which 6,000 distinct human membrane proteins (representing over 94% of the human membrane proteome, including single-pass, multi-pass, and GPI-anchored proteins, including GPCRs, ion channels, and transporters) are individually overexpressed in live cells by plasmids transfection in separate wells of a 384-well plate.

Article Title: Generation of chimeric antigen receptor T cells targeting p95HER2 in solid tumors
Article Snippet: The Membrane Proteome Array (MPA) screening was conducted at Integral Molecular, Inc. (Philadelphia, PA, USA).

Article Title: A preclinical study of allogeneic CD19 chimeric antigen receptor double‐negative T cells as an off‐the‐shelf immunotherapy drug against B‐cell malignancies
Article Snippet: Membrane proteome array (MPA) screening was conducted by Integral Molecular, Inc. (Shanghai, China).

Article Title: Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer.
Article Snippet: Membrane proteome array assay Integral Molecular, Inc. (Philadelphia, PA) performed specificity testing of IgG1 F12 using the Membrane Proteome Array (MPA) platform,25 in which 6,000 distinct human membrane proteins (representing over 94% of the human membrane proteome, including single-pass, multi-pass, and GPIanchored proteins, including GPCRs, ion channels, and transporters) are individually overexpressed in live cells by plasmids transfection in separate wells of a 384-well plate.

Article Title: MUC18-Directed chimeric antigen receptor T cells for the treatment of mucosal melanoma.
Article Snippet: Membrane proteome array (MPA) screening were conducted at Integral Molecular, Inc (PA, USA).

Article Title: Assessment of Novel Mesothelin-Specific Human Antibody Domain VH-Fc Fusion Proteins-Based PET Agents
Article Snippet: 3 Membrane Proteome Array (MPA) was performed by Integral Molecular, Inc. (Philadelphia, PA, USA) to specificity test VH-Fc 2A10 using the MPA platform, using the previously described sample preparation protocol16.

Membrane:

Article Title: A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells
Article Snippet: .. The membrane proteome array screen was conducted by Integral Molecular, Inc. (USA). ..



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Benzo-17R-RvD2 mimetic in peritonitis limits PMN tissue infiltration and regulates cytokines Mice were administered with vehicle or benzo-17R-RvD2 (1 ng/mouse) together with zymosan A (1 mg/mouse, i.p.) and exudates collected at 4 h. Total leukocytes were enumerated and composition determined by flow cytometry (see B for gating strategy). (A) Exudate PMN numbers; mean ± SEM, n = 4 mice each group, ∗∗ p < 0.01. (B) Proteome analysis was carried out with inflammatory exudates from four individual mice in each group using Proteome Profiler cytokine arrays, which contains 40 cytokines, chemokines, and acute phase proteins. Orthogonal Partial Least Squares Discriminant Analysis (PLS-DA): the score plot (each dot represents the cytokine profile from each mouse) shows clustering among groups (i.e., peritonitis vs. peritonitis plus benzo-17R-RvD2). The loading plot demonstrates correlations in which the measured cytokines contribute to the cluster separation in the score plot. (C) Relative intensities of cytokines, chemokines, and acute phase proteins. Proteome arrays consist of 40 proteins. Among them 18 were present in the peritoneal exudates. Results are mean ± SEM; relative abundance from n = 4 individual mouse exudates, ∗ p < 0.05, ∗∗ p < 0.01; peritonitis plus benzo-17R-RvD2 versus peritonitis alone; Student’s t test.

Journal: iScience

Article Title: Nouveau benzo-mimetics of 17R-Resolvin D2 are potent resolution agonists for inflammation

doi: 10.1016/j.isci.2025.114201

Figure Lengend Snippet: Benzo-17R-RvD2 mimetic in peritonitis limits PMN tissue infiltration and regulates cytokines Mice were administered with vehicle or benzo-17R-RvD2 (1 ng/mouse) together with zymosan A (1 mg/mouse, i.p.) and exudates collected at 4 h. Total leukocytes were enumerated and composition determined by flow cytometry (see B for gating strategy). (A) Exudate PMN numbers; mean ± SEM, n = 4 mice each group, ∗∗ p < 0.01. (B) Proteome analysis was carried out with inflammatory exudates from four individual mice in each group using Proteome Profiler cytokine arrays, which contains 40 cytokines, chemokines, and acute phase proteins. Orthogonal Partial Least Squares Discriminant Analysis (PLS-DA): the score plot (each dot represents the cytokine profile from each mouse) shows clustering among groups (i.e., peritonitis vs. peritonitis plus benzo-17R-RvD2). The loading plot demonstrates correlations in which the measured cytokines contribute to the cluster separation in the score plot. (C) Relative intensities of cytokines, chemokines, and acute phase proteins. Proteome arrays consist of 40 proteins. Among them 18 were present in the peritoneal exudates. Results are mean ± SEM; relative abundance from n = 4 individual mouse exudates, ∗ p < 0.05, ∗∗ p < 0.01; peritonitis plus benzo-17R-RvD2 versus peritonitis alone; Student’s t test.

Article Snippet: The supernatant (750 μl) was incubated with the pre-coated Proteome Profiler array membranes (ARY006, R&D Systems) and processed according to the manufacturer’s instructions.

Techniques: Flow Cytometry