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2026-04
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2026-04
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Chugai
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vs-5584 - by Bioz Stars,
2026-04
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2026-04
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2026-04
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S*BIO Pte Ltd
vs-5584 [5-(9-isopropyl-8-methyl-2-morpholin-4-yl-9h-purin-6-yl)-pyrimidin-2-ylamine] Vs 5584 [5 (9 Isopropyl 8 Methyl 2 Morpholin 4 Yl 9h Purin 6 Yl) Pyrimidin 2 Ylamine], supplied by S*BIO Pte Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/vs-5584 [5-(9-isopropyl-8-methyl-2-morpholin-4-yl-9h-purin-6-yl)-pyrimidin-2-ylamine]/product/S*BIO Pte Ltd Average 90 stars, based on 1 article reviews
vs-5584 [5-(9-isopropyl-8-methyl-2-morpholin-4-yl-9h-purin-6-yl)-pyrimidin-2-ylamine] - by Bioz Stars,
2026-04
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2026-04
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2026-04
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N/A
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VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM, respectively.
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N/A
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VS 5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin mTOR ICs 17 and 150 nM respectively It is a desmethyl analog of the dual PI3K mTOR inhibitor VS 5584 Item
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N/A
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Phosphatidylinositol 3 kinase PI3K signaling through Akt PKB and the mammalian target of rapamycin mTOR controls gene expression related to cell proliferation differentiation and apoptosis Increased activity of this pathway is important in many types
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