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Image Search Results
Journal: Heliyon
Article Title: Binding domain on CD22 molecules contributing to the biological activity of T cell-engaging bispecific antibodies
doi: 10.1016/j.heliyon.2023.e17960
Figure Lengend Snippet: CD3 + T cells proliferation and CD69 expression frequency on CD8 + and CD4 + T cells. (A) FACS histograms of CD3 + T cells proliferation for G5/44 BsAb (up line) and M971 BsAb (next line) on 2, 4 and 6 days. Green signal was the proliferated CD3 + T cells with the lower fluorescence intensity contributed by CD22-TCBs. (B) Column diagram of CD3 + T cells proliferation mediated by all six CD22-TCBs. (C) Expression frequency of CD69 on CD8 + and CD4 + T cells after 20 h incubation of huPBMCs with presence or absence of Raji cells or 100 ng/mL CD22-TCBs. Data were shown as mean ± SD (n = 3). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Article Snippet: Next, the cell mixture was harvested on day 2, 4 and 6 with labeling of
Techniques: Expressing, Fluorescence, Incubation
Journal: Journal of Experimental & Clinical Cancer Research : CR
Article Title: An immunometabolic prodrug strategy overcomes DHODH inhibitor resistance in refractory melanoma
doi: 10.1186/s13046-025-03566-6
Figure Lengend Snippet: H62 recruits and activates NK cell in vivo. A-B Flow cytometric analysis of NK (CD3 − NK1.1 + ) and C-D CD69 + cells in spleens of mice in various groups. E-F Flow cytometric analysis of NK (CD3 − NK1.1 + ) and G-H CD69 + cells in TDLNs of mice in various groups. I-J Flow cytometric analysis of NK (CD3 − NK1.1 + ) and K-L CD69 + cells in tumors of mice in various groups
Article Snippet: The antibody used in this study including
Techniques: In Vivo