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Inauhzin（Cat No.:I003092） is a compound that acts as a cell-permeable inhibitor of SIRT1, an enzyme involved in cellular processes and aging. It exhibits an inhibitory concentration (IC50) range of 0.7-2 μM against SIRT1. By inhibiting
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90
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Selleck Chemicals
inauhzin Inauhzin, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/inauhzin/Inauhzin/pmc09647175-43-3-6 Average 90 stars, based on 1 article reviews
inauhzin - by Bioz Stars,
2026-09
90/100 stars
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90
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Topscience Co Ltd
inauhzin Inauhzin, supplied by Topscience Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/inauhzin/inauhzin/pmc12082203-174-1-8 Average 90 stars, based on 1 article reviews
inauhzin - by Bioz Stars,
2026-09
90/100 stars
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90
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Merck KGaA
inauhzin Inauhzin, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/inauhzin/inauhzin/pmc05556267-624-33-34 Average 90 stars, based on 1 article reviews
inauhzin - by Bioz Stars,
2026-09
90/100 stars
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Inauhzin is a dual SirT1/IMPDH2 inhibitor, and acts as an activator p53, used in the research of cancer.
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InformationInauhzin is a cell-permeableSIRT1inhibitor with an IC50 of 0.7-2 μM and reactivatesp53by inhibiting SIRT1 deacetylation activity.TargetsSIRT1 ; p53In vitroInauhzin (INZ) is a potent p53 activator and mediates p53-dependent cytotoxicity. INZ inhibits cell proliferation by triggering
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Inauhzin is a potent SIRT inhibitor, which effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress. Moreover, Inauhzin stabilizes p53 by increasing p53 acetylation and
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