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pathhunter β-arrestin enzyme fragment complementation (efc) ![]() Pathhunter β Arrestin Enzyme Fragment Complementation (Efc), supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/fragmentation+enzyme/pmc10817531-248-17-6?v=DiscoverX+corporation Average 90 stars, based on 1 article reviews
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Biomol GmbH
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DiscoverX corporation
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DiscoverX corporation
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Promega
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DiscoverX corporation
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Quidel
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GenScript corporation
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Image Search Results
Journal: Marine Drugs
Article Title: Chlorinated Enyne Fatty Acid Amides from a Marine Cyanobacterium: Discovery of Taveuniamides L-M and Pharmacological Characterization of Taveuniamide F as a GPCR Antagonist with CNR1 Selectivity
doi: 10.3390/md22010028
Figure Lengend Snippet: GPCR profiling of taveuniamide F ( 4 ) using cell-based functional screen (β-arrestin pathway). ( a ) Heatmap showing the screening of 4 (20 μM) against 168 GPCR targets in agonist (% activation) and antagonist mode (% inhibition). ( b ) Scatter plot of targets screened at 20 μM of 4 . Hits identified in the screen with ≥75% activity or inhibitions are labeled. ( c ) Dose–response curve of 4 against GPCR hits identified in the PathHunter β-arrestin primary screen. ( d ) Dose–response curve of 4 against CNR1 and CNR2. The experiments were carried out as technical duplicates. Data are presented as mean ± SD ( n = 2).
Article Snippet: The experiments were carried out by
Techniques: Functional Assay, Activation Assay, Inhibition, Activity Assay, Labeling
Journal: Marine Drugs
Article Title: Chlorinated Enyne Fatty Acid Amides from a Marine Cyanobacterium: Discovery of Taveuniamides L-M and Pharmacological Characterization of Taveuniamide F as a GPCR Antagonist with CNR1 Selectivity
doi: 10.3390/md22010028
Figure Lengend Snippet: IC 50 of taveuniamide F ( 4 ) against GPCR targets identified in the PathHunter β-arrestin primary screen.
Article Snippet: The experiments were carried out by
Techniques: