cyc a Search Results


cyclosporin a  (TargetMol)
94
TargetMol cyclosporin a
Cyclosporin A, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cyclosporin a/product/TargetMol
Average 94 stars, based on 1 article reviews
cyclosporin a - by Bioz Stars, 2026-05
94/100 stars
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gene exp slc2a4 hs00168966 m1  (Thermo Fisher)
95
Thermo Fisher gene exp slc2a4 hs00168966 m1
Gene Exp Slc2a4 Hs00168966 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
gene exp slc2a4 hs00168966 m1 - by Bioz Stars, 2026-05
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anti cyc a  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology anti cyc a
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Anti Cyc A, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti cyc a/product/Santa Cruz Biotechnology
Average 93 stars, based on 1 article reviews
anti cyc a - by Bioz Stars, 2026-05
93/100 stars
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cyclopamine  (Selleck Chemicals)
95
Selleck Chemicals cyclopamine
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Cyclopamine, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cyclopamine/product/Selleck Chemicals
Average 95 stars, based on 1 article reviews
cyclopamine - by Bioz Stars, 2026-05
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lupasol ® fg  (BASF)
90
BASF lupasol ® fg
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Lupasol ® Fg, supplied by BASF, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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cyca smo inhibitor  (Curis Inc)
90
Curis Inc cyca smo inhibitor
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Cyca Smo Inhibitor, supplied by Curis Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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luciferase reporter constructs cyca-79/ 100  (Promega)
90
Promega luciferase reporter constructs cyca-79/ 100
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Luciferase Reporter Constructs Cyca 79/ 100, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
luciferase reporter constructs cyca-79/ 100 - by Bioz Stars, 2026-05
90/100 stars
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cdk2/cyca  (Nanosyn Inc)
90
Nanosyn Inc cdk2/cyca
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Cdk2/Cyca, supplied by Nanosyn Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdk2/cyca/product/Nanosyn Inc
Average 90 stars, based on 1 article reviews
cdk2/cyca - by Bioz Stars, 2026-05
90/100 stars
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cdk4/cycd1  (ProQinase GmbH)
90
ProQinase GmbH cdk4/cycd1
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Cdk4/Cycd1, supplied by ProQinase GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdk4/cycd1/product/ProQinase GmbH
Average 90 stars, based on 1 article reviews
cdk4/cycd1 - by Bioz Stars, 2026-05
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sterile vitamin b1 injection  (Zentiva Inc)
90
Zentiva Inc sterile vitamin b1 injection
v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. <t>(a)</t> <t>Immunoprecipitation</t> (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.
Sterile Vitamin B1 Injection, supplied by Zentiva Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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xrd spectral analysis rigaku ultima iv  (Rigaku Corporation)
90
Rigaku Corporation xrd spectral analysis rigaku ultima iv
<t>Lyophilized</t> <t>CycA</t> NSs composed of CycA: HPMC: SDS (1:1:0.5) after different homogenization cycles (pass number) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate
Xrd Spectral Analysis Rigaku Ultima Iv, supplied by Rigaku Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/xrd spectral analysis rigaku ultima iv/product/Rigaku Corporation
Average 90 stars, based on 1 article reviews
xrd spectral analysis rigaku ultima iv - by Bioz Stars, 2026-05
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cyca p2 promoter  (Blackwell Science Ltd)
90
Blackwell Science Ltd cyca p2 promoter
<t>Lyophilized</t> <t>CycA</t> NSs composed of CycA: HPMC: SDS (1:1:0.5) after different homogenization cycles (pass number) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate
Cyca P2 Promoter, supplied by Blackwell Science Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. (a) Immunoprecipitation (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.

Journal:

Article Title: v-Jun Overrides the Mitogen Dependence of S-Phase Entry by Deregulating Retinoblastoma Protein Phosphorylation and E2F-Pocket Protein Interactions as a Consequence of Enhanced Cyclin E-cdk2 Catalytic Activity

doi:

Figure Lengend Snippet: v-Jun enables cells to sustain cdk2 kinase activity and cyclin A expression after prolonged mitogen deprivation. (a) Immunoprecipitation (IP) kinase assays of total cdk2 and cyclin (cyc) A-cdk2 kinase activity in cultures of control and v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. Cell extracts were immunoprecipitated with antibodies specific for cdk2 (top) and cyclin A (bottom), and the precipitates were analyzed for kinase activity using histone H1 as a substrate. Subsequently, the precipitates were analyzed for cdk2 or cyclin A protein expression by Western blotting (WB). (b) DNA content cytograms of cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h. The plots correspond to the samples shown in panel d. (c) Cultures of v-Jun-transformed CEFs growing in GM or after incubation in LS medium for 48 h were labeled with BrdU for 2, 4, 6, or 8 h. The culture medium was changed immediately before BrdU addition to remove from the LS culture apoptotic cells which had died and detached prior to the start of the experiment. After being labeled, both adherent and detached cells were harvested, and the percentage of labeled cells was determined by flow cytometry. (d) Plots of DNA content versus BrdU incorporation for 8-h GM and LS medium samples shown in panel c. Labeled (L) and unlabeled (U) cell populations are indicated, as are the positions of G1, S, G2/M, and apoptotic (A) cells.

Article Snippet: The antisera used for Western blotting, and in some cases for immunoprecipitation, were as follows: anti-cdk2 (rabbit polyclonal; sc-163G; Santa Cruz), anti-cyc A (rabbit polyclonal; R28; kind gift of E. Nigg), cdk6 (anti-cdk6 Ab-1; Neomarkers), anti-cyc D1 (DCS-6), anti-cyc D2 (anti-cyclin D2 Ab-3; Neomarkers), anti-p27 KIP1 (PC52; Calbiochem), anti-Rb (14441A; Pharmingen), anti-p107 (sc318; Santa Cruz), and anti-p130 (sc31; Santa Cruz).

Techniques: Activity Assay, Expressing, Immunoprecipitation, Transformation Assay, Incubation, Western Blot, Labeling, Flow Cytometry, BrdU Incorporation Assay

v-Jun promotes mitogen-independent Rb phosphorylation and reaccumulation of cyclin A after mitosis. (a) Flow cytometry analysis of mitogen-deprived v-Jun CEFs separated by centrifugal elutriation. The starting population was separated into nine fractions (F1 to -9) of increasing size as determined by FSC. DNA content cytograms and FSC values of the unfractionated population (U) and successive fractions are shown. (b) Western blotting analysis of cyclin (cyc) A, cdk2, and Rb expression in the elutriated fractions shown in panel a.

Journal:

Article Title: v-Jun Overrides the Mitogen Dependence of S-Phase Entry by Deregulating Retinoblastoma Protein Phosphorylation and E2F-Pocket Protein Interactions as a Consequence of Enhanced Cyclin E-cdk2 Catalytic Activity

doi:

Figure Lengend Snippet: v-Jun promotes mitogen-independent Rb phosphorylation and reaccumulation of cyclin A after mitosis. (a) Flow cytometry analysis of mitogen-deprived v-Jun CEFs separated by centrifugal elutriation. The starting population was separated into nine fractions (F1 to -9) of increasing size as determined by FSC. DNA content cytograms and FSC values of the unfractionated population (U) and successive fractions are shown. (b) Western blotting analysis of cyclin (cyc) A, cdk2, and Rb expression in the elutriated fractions shown in panel a.

Article Snippet: The antisera used for Western blotting, and in some cases for immunoprecipitation, were as follows: anti-cdk2 (rabbit polyclonal; sc-163G; Santa Cruz), anti-cyc A (rabbit polyclonal; R28; kind gift of E. Nigg), cdk6 (anti-cdk6 Ab-1; Neomarkers), anti-cyc D1 (DCS-6), anti-cyc D2 (anti-cyclin D2 Ab-3; Neomarkers), anti-p27 KIP1 (PC52; Calbiochem), anti-Rb (14441A; Pharmingen), anti-p107 (sc318; Santa Cruz), and anti-p130 (sc31; Santa Cruz).

Techniques: Flow Cytometry, Western Blot, Expressing

Lyophilized CycA NSs composed of CycA: HPMC: SDS (1:1:0.5) after different homogenization cycles (pass number) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: Lyophilized CycA NSs composed of CycA: HPMC: SDS (1:1:0.5) after different homogenization cycles (pass number) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Homogenization

SEM images of (A) CycA coarse powder (mag. 1000x), (B) HPMC (mag. 1000x), (C) SDS (mag. 1000x), (D) mannitol (mag. 1000x), (E) the PM (mag. 1000x), (F) the CycA NS (mag. 500x) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, PM: Physical mixture, mag.: Magnification, SEM: Scanning electron microscopy

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: SEM images of (A) CycA coarse powder (mag. 1000x), (B) HPMC (mag. 1000x), (C) SDS (mag. 1000x), (D) mannitol (mag. 1000x), (E) the PM (mag. 1000x), (F) the CycA NS (mag. 500x) CycA: Cyclosporine A, NSs: Nanosuspensions, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, PM: Physical mixture, mag.: Magnification, SEM: Scanning electron microscopy

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Electron Microscopy

XRD patterns of CycA NS, CycA coarse powder, HPMC, SDS, mannitol, and the PM XRD: X-ray powder diffraction, CycA: Cyclosporine A, NS: Nanosuspension, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, PM: Physical mixture

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: XRD patterns of CycA NS, CycA coarse powder, HPMC, SDS, mannitol, and the PM XRD: X-ray powder diffraction, CycA: Cyclosporine A, NS: Nanosuspension, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, PM: Physical mixture

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques:

FTIR spectra of the CycA coarse powder, HPMC, SDS, mannitol, PM, and CycA NS FTIR: Fourier transform infrared radiation, CycA: Cyclosporine A, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, NS: Nanosuspension, PM: Physical mixture

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: FTIR spectra of the CycA coarse powder, HPMC, SDS, mannitol, PM, and CycA NS FTIR: Fourier transform infrared radiation, CycA: Cyclosporine A, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, NS: Nanosuspension, PM: Physical mixture

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Fourier Transform Infrared Spectroscopy

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet:

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Solubility

Dissolution profiles of CycA coarse powder, a commercial product, and a PM of CycA NS in (A) 0.1 N HCl containing 0.5% SDS and (B) 0.1 N HClCycA: Cyclosporine A, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, NS: Nanosuspension, PM: Physical mixture, HCl: Hydrochloric acid

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: Dissolution profiles of CycA coarse powder, a commercial product, and a PM of CycA NS in (A) 0.1 N HCl containing 0.5% SDS and (B) 0.1 N HClCycA: Cyclosporine A, HPMC: Hydroxypropyl methylcellulose, SDS: Sodium dodecyl sulfate, NS: Nanosuspension, PM: Physical mixture, HCl: Hydrochloric acid

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Dissolution

Dissolution profiles of the CycA coarse powder, commercial product, and PM as well as the CycA NS in (A) FaSSIF medium and (B) FeSSIF medium CycA: Cyclosporine A, PM: Physical mixture, FaSSIF: Fasted simulated intestinal fluid, FeSSIF: Fed simulated intestinal fluid

Journal: Turkish Journal of Pharmaceutical Sciences

Article Title: Development of Cyclosporine A Nanosuspension Using an Experimental Design Based on Response Surface Methodology: In Vitro Evaluations

doi: 10.4274/tjps.galenos.2023.68054

Figure Lengend Snippet: Dissolution profiles of the CycA coarse powder, commercial product, and PM as well as the CycA NS in (A) FaSSIF medium and (B) FeSSIF medium CycA: Cyclosporine A, PM: Physical mixture, FaSSIF: Fasted simulated intestinal fluid, FeSSIF: Fed simulated intestinal fluid

Article Snippet: The XRD spectral analysis of the CycA coarse powder, stabilizers, PM, and lyophilized NS was carried out by Rigaku Ultima ® IV (Japan).

Techniques: Dissolution