Journal: Aging (Albany NY)

Article Title: Tonsil mesenchymal stem cells-derived extracellular vesicles prevent submandibular gland dysfunction in ovariectomized rats

doi: 10.18632/aging.203947

Figure Lengend Snippet: Increased salivary gland function by injected T-MSCs-derived extracellular vesicles. The AQP5- and α-amylase-positive areas significantly decreased in the OVX groups compared with those in the SHAM group. However, AQP5 and α-amylase expression increased in the OVX+EV treatment group ( A and B ). The mRNA expression of AQP3 and AQP5 decreased in the OVX group and increased mRNA expression of AQP3 and AQP5 in the OVX+EV treatment group, compared with that in the SHAM group ( C ). One-way ANOVA test; and * p < 0.05 and *** p < 0.001 vs. SHAM, # p < 0.05 and ## p < 0.01 vs. OVX.

Article Snippet: For quantitative analyses of collagen I, TGF βI, AQP5 and α-amylase expression, de-paraffinized sections were incubated for 24 h at 4°C with the following primary antibodies: anti-collagen I, TGF βI and AQP5 (200 ug/mL) (Santa Cruz Biotechnology, Dallas, TA, USA), anti- α-amylase (1:400) (Abcam, Cambridge, UK).

Techniques: Injection, Derivative Assay, Expressing

Journal: Aging (Albany NY)

Article Title: Tonsil mesenchymal stem cells-derived extracellular vesicles prevent submandibular gland dysfunction in ovariectomized rats

doi: 10.18632/aging.203947

Figure Lengend Snippet: Primers.

Article Snippet: For quantitative analyses of collagen I, TGF βI, AQP5 and α-amylase expression, de-paraffinized sections were incubated for 24 h at 4°C with the following primary antibodies: anti-collagen I, TGF βI and AQP5 (200 ug/mL) (Santa Cruz Biotechnology, Dallas, TA, USA), anti- α-amylase (1:400) (Abcam, Cambridge, UK).

Techniques: Sequencing