M00159 Search Results


cdk4  (Boster Bio)
94
Boster Bio cdk4
Figure 3. PD induced cell cycle arrest in the G0/G1 phase in MDA-MB-231 cells. (A) Cells were exposed to 2.5, 5, 10 or 20 µM of PD for 48 h and the cell cycle progression was assessed by flow cytometry. The 5, 10 and 20 µM concentrations of PD induced significant cell cycle arrest in the G0/G1 phase. (B and C) The expression levels of G0/G1 phase-related proteins was analyzed by western blotting after treatment with various concentrations of PD for 24 h. PD down regulated the expression of CDK2, <t>CDK4,</t> CDK6, and Cyclin E. (*p<0.05).
Cdk4, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdk4/product/Boster Bio
Average 94 stars, based on 1 article reviews
cdk4 - by Bioz Stars, 2026-04
94/100 stars
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rabbit anticdk4 monoclonal antibody  (Boster Bio)
90
Boster Bio rabbit anticdk4 monoclonal antibody
Figure 3. PD induced cell cycle arrest in the G0/G1 phase in MDA-MB-231 cells. (A) Cells were exposed to 2.5, 5, 10 or 20 µM of PD for 48 h and the cell cycle progression was assessed by flow cytometry. The 5, 10 and 20 µM concentrations of PD induced significant cell cycle arrest in the G0/G1 phase. (B and C) The expression levels of G0/G1 phase-related proteins was analyzed by western blotting after treatment with various concentrations of PD for 24 h. PD down regulated the expression of CDK2, <t>CDK4,</t> CDK6, and Cyclin E. (*p<0.05).
Rabbit Anticdk4 Monoclonal Antibody, supplied by Boster Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anticdk4 monoclonal antibody/product/Boster Bio
Average 90 stars, based on 1 article reviews
rabbit anticdk4 monoclonal antibody - by Bioz Stars, 2026-04
90/100 stars
  Buy from Supplier

Image Search Results


Figure 3. PD induced cell cycle arrest in the G0/G1 phase in MDA-MB-231 cells. (A) Cells were exposed to 2.5, 5, 10 or 20 µM of PD for 48 h and the cell cycle progression was assessed by flow cytometry. The 5, 10 and 20 µM concentrations of PD induced significant cell cycle arrest in the G0/G1 phase. (B and C) The expression levels of G0/G1 phase-related proteins was analyzed by western blotting after treatment with various concentrations of PD for 24 h. PD down regulated the expression of CDK2, CDK4, CDK6, and Cyclin E. (*p<0.05).

Journal: Oncology reports

Article Title: Platycodin D, a metabolite of Platycodin grandiflorum, inhibits highly metastatic MDA-MB-231 breast cancer growth in vitro and in vivo by targeting the MDM2 oncogene.

doi: 10.3892/or.2016.4935

Figure Lengend Snippet: Figure 3. PD induced cell cycle arrest in the G0/G1 phase in MDA-MB-231 cells. (A) Cells were exposed to 2.5, 5, 10 or 20 µM of PD for 48 h and the cell cycle progression was assessed by flow cytometry. The 5, 10 and 20 µM concentrations of PD induced significant cell cycle arrest in the G0/G1 phase. (B and C) The expression levels of G0/G1 phase-related proteins was analyzed by western blotting after treatment with various concentrations of PD for 24 h. PD down regulated the expression of CDK2, CDK4, CDK6, and Cyclin E. (*p<0.05).

Article Snippet: The antibodies against human CDK2, CDK4, CDK6, and Cyclin E used in the western blot analyses were obtained from Boster Biotechnology (Wuhan, China).

Techniques: Flow Cytometry, Expressing, Western Blot

Figure 9. The effects of PD on the expression levels of various proteins in MDA-MB-231 xenograft tumors. Western blotting was performed to assess the expression levels of proteins in the MDM2-MDMX-p53 pathway, down- stream proteins and G0/G1 phase-related proteins in mice after treatment with the three concentrations of PD for four weeks. (A) PD downregulated the expression of the MDM2, MDMX, and mutant p53 proteins. (B) PD upregulated the expression of p21 and p27. (C) PD decreased the expression of G0/G1 phase-related proteins (CDK2, CDK4, CDK6 and Cyclin E).

Journal: Oncology reports

Article Title: Platycodin D, a metabolite of Platycodin grandiflorum, inhibits highly metastatic MDA-MB-231 breast cancer growth in vitro and in vivo by targeting the MDM2 oncogene.

doi: 10.3892/or.2016.4935

Figure Lengend Snippet: Figure 9. The effects of PD on the expression levels of various proteins in MDA-MB-231 xenograft tumors. Western blotting was performed to assess the expression levels of proteins in the MDM2-MDMX-p53 pathway, down- stream proteins and G0/G1 phase-related proteins in mice after treatment with the three concentrations of PD for four weeks. (A) PD downregulated the expression of the MDM2, MDMX, and mutant p53 proteins. (B) PD upregulated the expression of p21 and p27. (C) PD decreased the expression of G0/G1 phase-related proteins (CDK2, CDK4, CDK6 and Cyclin E).

Article Snippet: The antibodies against human CDK2, CDK4, CDK6, and Cyclin E used in the western blot analyses were obtained from Boster Biotechnology (Wuhan, China).

Techniques: Expressing, Western Blot, Mutagenesis