HY-144130 Search Results


sr3335  (MedChemExpress)
94
MedChemExpress sr3335
Effect of the <t>RORα/RORγ/P65</t> on the Bcl-2/Bax and TNF-α/IL-6 expression. (A) Protein levels of Bcl-2; (B) protein levels of Bax; (C) TNF-α concentrations; (D) IL-6 concentrations. <t>SR3335:</t> RORα antagonist (5 μM); SR1078: RORα and RORγ agonist (10 μM); BAY: P65 antagonist (1 μM); ConA: 20 µg/mL, Melatonin: 10 −9 M. Data are presented as the means ± SEM. Different letters on the column indicate significant differences compared with the control group ( P < 0.05).
Sr3335, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/HY-144130/SR3335/pmc10764265-77-6-12
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sr3335 - by Bioz Stars, 2026-09
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Effect of the RORα/RORγ/P65 on the Bcl-2/Bax and TNF-α/IL-6 expression. (A) Protein levels of Bcl-2; (B) protein levels of Bax; (C) TNF-α concentrations; (D) IL-6 concentrations. SR3335: RORα antagonist (5 μM); SR1078: RORα and RORγ agonist (10 μM); BAY: P65 antagonist (1 μM); ConA: 20 µg/mL, Melatonin: 10 −9 M. Data are presented as the means ± SEM. Different letters on the column indicate significant differences compared with the control group ( P < 0.05).

Journal: Poultry Science

Article Title: The signal pathway of melatonin mediates the monochromatic light-induced T-lymphocyte apoptosis in chicken thymus

doi: 10.1016/j.psj.2023.103331

Figure Lengend Snippet: Effect of the RORα/RORγ/P65 on the Bcl-2/Bax and TNF-α/IL-6 expression. (A) Protein levels of Bcl-2; (B) protein levels of Bax; (C) TNF-α concentrations; (D) IL-6 concentrations. SR3335: RORα antagonist (5 μM); SR1078: RORα and RORγ agonist (10 μM); BAY: P65 antagonist (1 μM); ConA: 20 µg/mL, Melatonin: 10 −9 M. Data are presented as the means ± SEM. Different letters on the column indicate significant differences compared with the control group ( P < 0.05).

Article Snippet: The chemical blocker contains: 5 μM SR3335 (a selective RORα inverse agonist; MCE, NJ), 10 μM SR1078 (a nonselective agonist of the nuclear receptor RORα and RORγ; MCE, NJ), 1 μM BAY (an antagonist of P65; MCE, NJ).

Techniques: Expressing, Control